Search Results - "VALERI, C. R"

Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin : Studies in baboons, human coronary intervention, and human acute myocardial infarction by MICHELSON, Alan D, BARNARD, Marc R, KRUEGER, Lori A, VALERI, C. Robert, FURMAN, Mark I

“…Platelet surface P-selectin is considered the "gold standard" marker of platelet activation. Degranulated, P-selectin-positive platelets, however, aggregate…”
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Nitric Oxide Circulates in Mammalian Plasma Primarily as an S-Nitroso Adduct of Serum Albumin by Stamler, Jonathan S., Jaraki, Omar, Osborne, John, Simon, Daniel I., Keaney, John, Vita, Joseph, Singel, David, Valeri, C. Robert, Loscalzo, Joseph

“…We have recently shown that nitric oxide or authentic endothelium-derived relaxing factor generated in a biologic system reacts in the presence of specific…”
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Increased Platelet Reactivity and Circulating Monocyte-Platelet Aggregates in Patients With Stable Coronary Artery Disease by Furman, Mark I, Benoit, Stephen E, Barnard, Marc R, Valeri, C.Robert, Borbone, Marie L, Becker, Richard C, Hechtman, Herbert B, Michelson, Alan D

“…Objectives. We sought to examine whether patients with stable coronary artery disease (CAD) have increased platelet reactivity and an enhanced propensity to…”
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In vivo Tracking of Platelets: Circulating Degranulated Platelets Rapidly Lose Surface P-Selectin but Continue to Circulate and Function by Michelson, Alan D., Barnard, Marc R., Hechtman, Herbert B., MacGregor, Hollace, Connolly, Raymond J., Loscalzo, Joseph, Valeri, C. Robert

“…To examine the hypothesis that surface P-selectin-positive (degranulated) platelets are rapidly cleared from the circulation, we developed novel methods for…”
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Pathophysiology of ischaemia reperfusion injury: central role of the neutrophil by Welbourn, C R, Goldman, G, Paterson, I S, Valeri, C R, Shepro, D, Hechtman, H B

“…Ischaemia is a common clinical event leading to local and remote injury. Evidence indicates that tissue damage is largely caused by activated neutrophils which…”
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Correlation between in vitro aggregation and thromboxane A2 production in fresh, liquid-preserved, and cryopreserved human platelets: effect of agonists, pH, and plasma and saline resuspension by Valeri, C.R., Macgregor, H., Ragno, G.

“…BACKGROUND: Some of the tests used to assess the quality of fresh and preserved platelets (PLTs) include PLT number, PLT morphology, pH of the PLT medium, PLT…”
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Comparison of the effects of transfusions of cryopreserved and liquid-preserved platelets on hemostasis and blood loss after cardiopulmonary bypass by Khuri, Shukri F., Healey, Nancy, MacGregor, Hollace, Barnard, Marc R., Szymanski, Irma O., Birjiniuk, Vladimir, Michelson, Alan D., Gagnon, David R., Valeri, C.Robert

“…Objective: The aim of the study was to compare the clinical effects and hemostatic efficiency of transfusions of platelets preserved in the frozen state for as…”
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Exploring the feasibility of selective depletion of T lymphocyte subsets by whole blood immunoadsorption cytapheresis by Belak, M, Valeri, C.R, Wright, D.G

“…Normal turnover of T lymphocytes is slow relative to other blood cells. Consequently, the physical removal of circulating leucocytes by thoracic duct drainage,…”
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The Platelet Function Defect of Cardiopulmonary Bypass by Kestin, Anita S., Valeri, C. Robert, Khuri, Shukri F., Loscalzo, Joseph, Ellis, Patricia A., MacGregor, Hollace, Birjiniuk, Vladimir, Ouimet, Helene, Pasche, Boris, Nelson, Martha J., Benoit, Stephen E., Rodino, Louis J., Barnard, Marc R., Michelson, Alan D.

“…The use of cardiopulmonary bypass (CPB) during cardiac surgery is associated with a hemostatic defect, the hallmark of which is a markedly prolonged bleeding…”
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Effects of temperature on bleeding time and clotting time in normal male and female volunteers by Valeri, C. Robert, MacGregor, Hollace, Cassidy, George, Tinney, Robin, Pompei, Francesco

“…OBJECTIVEThis study was done to assess the effects of temperature on bleeding time and clotting time in normal male and female volunteers. DESIGNOpen study…”
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Effect of 24-hour whole-blood storage on plasma clotting factors by O'NEILL, E. M, ROWLEY, J, HANSSON-WICHER, M, MCCARTER, S, RAGNO, G, VALERI, C. R

“…The current requirements for the preparation of fresh-frozen plasma within 8 hours of whole-blood collection were designed to maintain clotting factor…”
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In vitro testing of fresh and lyophilized reconstituted human and baboon platelets by Valeri, C.R., Macgregor, H., Barnard, M.R., Summaria, L., Michelson, A.D., Ragno, G.

“…BACKGROUND:  Studies have been performed on human fresh, liquid‐preserved, and cryopreserved platelets (PLTs) to assess PLT‐adhesive surface receptors, PLT…”
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Expired liquid preserved platelet releasates retain proliferative activity by CHAN, Rodney K, LIU, Perry, LEW, Dae-Hyun, IBRAHIM, Shahrul I, SREY, Rithy, VALERI, C. R, HECHTMAN, Herbert B, ORGILL, Dennis P

“…Donated platelets for clinical use currently have a shelf life of 5 days as the result of possible bacterial contamination and loss of hemostatic function…”
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Electrical alternans and cardiac electrical instability by SMITH, J. M, CLANCY, E. A, VALERI, C. R, RUSKIN, J. N, COHEN, R. J

“…We investigated the relationship between electrical alternans and cardiac electrical stability in a series of 20 dog experiments and in a pilot clinical study…”
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The red cell transfusion trigger: has a sin of commission now become a sin of omission? by Valeri, C. R., Crowley, J. P., Loscalzo, J.

“…The benefits of a Hct range of 30 to 35 percent include improved oxygen delivery and enhanced hemostasis, which help minimize complications in patients at high…”
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Glycerol hyperhydration: hormonal, renal, and vascular fluid responses by Freund, B J, Montain, S J, Young, A J, Sawka, M N, DeLuca, J P, Pandolf, K B, Valeri, C R

“…Glycerol ingestion has been shown to mediate hyperhydration; however, the mechanism(s) responsible for this improved fluid retention is not well understood…”
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Reversible inhibition of human platelet activation by hypothermia in vivo and in vitro by Michelson, A D, MacGregor, H, Barnard, M R, Kestin, A S, Rohrer, M J, Valeri, C R

“…A hypothermia-induced hemorrhagic diathesis is associated with cardiopulmonary bypass, major surgery, and multiple trauma, but its pathophysiological basis is…”
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Stroma-free hemoglobin increases blood pressure and GFR in the hypotensive rat: role of nitric oxide by Thompson, A, McGarry, A E, Valeri, C R, Lieberthal, W

“…The short-term systemic and renal hemodynamic effects of two stroma-free hemoglobin (SFH) solutions, one unmodified and the other modified by cross-linking,…”
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Reinfusion of shed blood after orthopaedic procedures in children and adolescents by Blevins, F T, Shaw, B, Valeri, C R, Kasser, J, Hall, J

“…A prospective study was done of the results of infusion of drained blood after major procedures on the spine and hip in twenty-six patients. The Solcotrans…”
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Restoration of red blood cell volume following 2-unit red blood cell apheresis by Valeri, C. R., Ragno, G., Srey, R.

“…Background and Objectives Blood donors who weigh at least 130 lbs (59 kg) and have a haematocrit of at least 40 V per cent can donate 2 units of blood, from…”
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