Search Results - "VALENZUELA, FERNÁN GÓMEZ"

The Inflammatory Profile of the Tumor Microenvironment, Orchestrated by Cyclooxygenase-2, Promotes Epithelial-Mesenchymal Transition by Gómez-Valenzuela, Fernán, Escobar, Enrico, Pérez-Tomás, Ricardo, Montecinos, Viviana P.

“…The tumor microenvironment (TME) corresponds to a complex and dynamic interconnection between the extracellular matrix and malignant cells and their…”
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Cyclooxygenase‐2 protein expression modulates cell proliferation and apoptosis in solid ameloblastoma and odontogenic keratocyst. An immunohistochemical study by Escobar, Enrico, Peñafiel, Cristian, Gómez‐Valenzuela, Fernán, Chimenos‐Küstner, Eduardo, Pérez‐Tomás, Ricardo

“…Background Cyclooxygenase‐2 protein is a critically important mediator in inflammation that influences proliferation, apoptosis, angiogenesis and metastasis…”
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The Challenge by Multiple Environmental and Biological Factors Induce Inflammation in Aging: Their Role in the Promotion of Chronic Disease by Bachmann, María Consuelo, Bellalta, Sofía, Basoalto, Roque, Gómez-Valenzuela, Fernán, Jalil, Yorschua, Lépez, Macarena, Matamoros, Anibal, von Bernhardi, Rommy

“…The aging process is driven by multiple mechanisms that lead to changes in energy production, oxidative stress, homeostatic dysregulation and eventually to…”
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Mechanical Disturbance of Osteoclasts Induces ATP Release That Leads to Protein Synthesis in Skeletal Muscle through an Akt-mTOR Signaling Pathway by Morales-Jiménez, Camilo, Balanta-Melo, Julián, Arias-Calderón, Manuel, Hernández, Nadia, Gómez-Valenzuela, Fernán, Escobar, Alejandro, Jaimovich, Enrique, Buvinic, Sonja

“…Muscle and bone are tightly integrated through mechanical and biochemical signals. Osteoclasts are cells mostly related to pathological bone loss; however,…”
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Immunohistochemical evaluation of cyclin D1 and p63 in odontogenic keratocyst and unicystic ameloblastoma by Escobar, Enrico, Gómez-Valenzuela, Fernán, Peñafiel, Cristian, Chimenos-Küstner, Eduardo, Pérez-Tomás, Ricardo

“…Odontogenic keratocyst (OKC) and unicystic ameloblastoma (UA) are lesions of odontogenic origin. Both lesions are morphologically cysts. However, they are…”
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Immunohistochemical expression of COX-2, Ki-67, Bcl-2, Bax, VEGF and CD105 according to histological grading in oral squamous cell carcinoma by Escobar, Enrico, Gómez-Valenzuela, Fernán, Peñafiel, Cristian, Hormazábal-Hevia, Alondra, Herrera-Fuentes, Constanza, Mori-Aliaga, Diana

“…Oral squamous cell carcinoma (OSCC) is the most prevalent head and neck cancer. Few studies have analyzed the expression of proteins related to inflammation…”
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Aberrant immunoexpression of p53 tumour-suppressor and Bcl-2 family proteins (Bcl-2 and Bax) in ameloblastomas and odontogenic keratocysts by Escobar, Enrico, Gómez-Valenzuela, Fernán, Peñafiel, Cristian, Chimenos-Küstner, Eduardo, Pérez-Tomás, Ricardo

“…The growth of ameloblastomas (odontogenic tumours) and odontogenic keratocyst (OKC) (developmental cyst) is associated with the expression of proteins related…”
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CYCLOOXYGENASE-2 AND ANGIOGENESIS IN ORAL SQUAMOUS CELL CARCINOMA: AN IMMUNOHISTOCHEMICAL STUDY by HEVIA, ALONDRA HORMAZÁBAL, ALIAGA, DIANA MORI, PINTO, ANA ORTEGA, VALENZUELA, FERNÁN GÓMEZ, EKDHAL, CRISTIAN PEÑAFIEL, LÓPEZ, ENRICO ESCOBAR

“…Cyclooxygenase-2 (cox-2) overexpression is linked to carcinogenesis and maintenance of progressive tumor growth. Angiogenesis plays a crucial role in…”
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ADENOMATOID ODONTOGENIC TUMOR. A CLINICAL-PATHOLOGIC STUDY OF 27 CASES by ALIAGA, DIANA GABRIELA MORI, HEVIA, ALONDRA HORMAZÁBAL, SANTANDER, IRIS ESPINOZA, PINTO, ANA ORTEGA, VALENZUELA, FERNÁN GÓMEZ, EKDHAL, CRISTIAN PEÑAFIEL, LÓPEZ, ENRICO ESCOBAR

“…Adenomatoid odontogenic tumor (AOT) is a benign (hamartomatous), noninvasive lesion with slow but progressive growth. The 3 variants—follicular,…”
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Odontogenic tumours in a Chilean population: a retrospective study of 544 cases based on 2022 WHO classification by Escobar, E, Gómez-Valenzuela, F, Peñafiel, C, Ortega-Pinto, A

“…Odontogenic tumours are infrequent lesions. Studies on the frequency of odontogenic tumours from Latin America are scarce. This work aimed to determine the…”
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Cyclooxygenase-2 Blockade Is Crucial to Restore Natural Killer Cell Activity before Anti-CTLA-4 Therapy against High-Grade Serous Ovarian Cancer by Gómez-Valenzuela, Fernán, Wichmann, Ignacio, Suárez, Felipe, Kato, Sumie, Ossandón, Enrique, Hermoso, Marcela, Fernández, Elmer A, Cuello, Mauricio A

“…Chronic inflammation influences the tumor immune microenvironment (TIME) in high-grade serous ovarian cancer (HGSOC). Specifically, cyclooxygenase-2 (COX-2)…”
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Abstract 182: Cyclooxygenase-2 blockade is crucial to restore natural killer cell activity before anti-CTLA-4 therapy against high-grade serous ovarian cancer by Gomez-Valenzuela, Fernan, Wichmann, Ignacio, Suárez, Felipe, Kato, Sumie, Ossandón, Enrique, Hermoso, Marcela, Fernández, Elmer, Cuello, Mauricio A.

“…Objective: Here our goal was to evaluate the impact of the immunosuppressive enzyme cyclooxygenase-2 (COX-2) expression on the immune effector capacity against…”
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