Search Results - "VALCARCEL, M"
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Treatment with the mitochondrial‐targeted antioxidant peptide SS‐31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice
Published in Aging cell (01-04-2018)“…Summary Moment‐to‐moment adjustment of cerebral blood flow (CBF) via neurovascular coupling has an essential role in maintenance of healthy cognitive function…”
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Rapid and simple nanosensor by combination of graphene quantum dots and enzymatic inhibition mechanisms
Published in Sensors and actuators. B, Chemical (01-03-2017)“…[Display omitted] •Graphene quantum dots are proposed as fluorescent probes for fenoxycarb determination.•Acetylcholinesterase was chosen as biorecognition…”
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One step carbon nanotubes-based solid-phase extraction for the gas chromatographic–mass spectrometric multiclass pesticide control in virgin olive oils
Published in Journal of Chromatography A (23-10-2009)“…This article presents a novel application of carbon nanotubes for the determination of pesticides (chlortoluron, diuron, atrazine, simazine,…”
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IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging
Published in Aging cell (01-12-2015)“…Summary Aging is associated with marked deficiency in circulating IGF‐1, which has been shown to contribute to age‐related cognitive decline. Impairment of…”
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Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (14-06-2018)“…Obesity has deleterious effects on cognitive function in the elderly adults. In mice, aging exacerbates obesity-induced oxidative stress, microvascular…”
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Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-08-2012)“…The redox-sensitive transcription factor NF-E2-related factor 2 (Nrf2) plays a key role in preserving a healthy endothelial phenotype and maintaining the…”
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Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex
Published in American journal of physiology. Heart and circulatory physiology (01-12-2015)“…Impairment of moment-to-moment adjustment of cerebral blood flow (CBF) via neurovascular coupling is thought to play a critical role in the genesis of…”
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Microextraction techniques
Published in Analytical and bioanalytical chemistry (01-03-2014)“…Issue Title: Microextraction techniques…”
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Membrane set up combined with photoionization-ion mobility spectrometer to improve analytical performance and avoid humidity interference on the determination of aromatics in gaseous samples
Published in Journal of Chromatography A (29-01-2016)“…•Humidity influence on the mobility spectra of BTX measured by UV-IMS was studied.•A membrane set up coupled to UV-IMS was proposed to avoid humidity…”
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Sustainable cultivation of melon landraces: Effects of grafting on the accumulation of flavor-related compounds
Published in Food chemistry (30-06-2024)“…•The effects of grafting on acid accumulation are negligible.•Sugar accumulation and profile are affected by grafting.•Grafing effects on sugars depend on…”
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Evaluation of phenylene-bridged periodic mesoporous organosilica as a stationary phase for solid phase extraction
Published in Journal of Chromatography A (28-11-2014)“…•A Ph-PMO was successfully used as sorbent for extraction of selected pesticides.•The selectivity of Ph-PMO was similar to that of commercial C18 and…”
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Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-08-2013)“…Age-related impairment of angiogenesis is likely to play a central role in cerebromicrovascular rarefaction and development of vascular cognitive impairment,…”
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Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-04-2012)“…Recent studies demonstrate that age-related dysfunction of NF-E2-related factor-2 (Nrf2)-driven pathways impairs cellular redox homeostasis, exacerbating…”
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Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment
Published in GeroScience (01-08-2017)“…Strong epidemiological and experimental evidence indicates that hypertension has detrimental effects on the cerebral microcirculation and thereby promotes…”
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Determination of carboxylic SWCNTs in river water by microextraction in ionic liquid and determination by Raman spectroscopy
Published in Talanta (Oxford) (15-02-2013)“…The paper proposes a simple approach for the preconcentration of carboxylated single-walled carbon nanotubes and their determination in river water samples…”
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Coiled carbon nanotubes combined with ionic liquid: a new soft material for SPE
Published in Analytical and bioanalytical chemistry (01-08-2012)“…For the first time a soft material formed from coiled carbon nanotubes and 1-hexyl-3-methylimidazolium hexafluorophosphate has been used as sorbent material…”
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Bridging the Gap: Assessing Material Performance of Laboratory Specimens and Concrete Structures
Published in Materials (10-06-2023)“…Chloride ingress and carbonation pose a significant risk of steel rebar corrosion in concrete structures. Various models exist to simulate the initiation phase…”
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ModelArray: An R package for statistical analysis of fixel-wise data
Published in NeuroImage (Orlando, Fla.) (01-05-2023)“…•ModelArray is an R package for statistical analysis of fixel-wise data.•ModelArray supports linear and nonlinear modeling and is extensible to more…”
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Analytical nanoscience and nanotechnology today and tomorrow
Published in Analytical and bioanalytical chemistry (01-07-2008)“…This article discusses the mutual impact of nanotechnology and analytical science and illustrates how this technical trend can be expected to strengthen the…”
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Nanomaterials for improved analytical processes
Published in Analytical and bioanalytical chemistry (2011)Get full text
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