Search Results - "VACHA, Jiri"
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Two MMP-2 promoter polymorphisms (-790T/G and -735C/T) in chronic heart failure
Published in Clinical chemistry and laboratory medicine (01-10-2003)“…Remodelling of extracellular matrix by activated matrix metalloproteinases is considered to contribute to progression of ventricle remodelling during chronic…”
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Drugs elevating extracellular adenosine promote regeneration of haematopoietic progenitor cells in severely myelosuppressed mice: their comparison and joint effects with the granulocyte colony-stimulating factor
Published in European journal of haematology (01-01-2002)“…: We tested capabilities of drugs elevating extracellular adenosine and of granulocyte colony‐stimulating factor (G‐CSF) given alone or in combination to…”
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Endothelin-1 gene polymorphism in the identification of patients at risk for malignant ventricular arrhythmia
Published in Medical science monitor (01-05-2002)“…The endothelins are peptides with vasoconstricting and growth-promoting properties. Endothelin-1 (ET-1) is known for its direct positive inotropic and…”
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I/D ACE gene polymorphism in survival of leukemia patients – hypothesis and pilot study
Published in Medical hypotheses (01-07-2003)“…Angiotensin-I converting enzyme (ACE) is involved not only in intracellular volume regulation but also in proliferation control. Since both ACE gene…”
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The C766T low-density lipoprotein receptor related protein polymorphism and coronary artery disease, plasma lipoproteins, and longevity in the Czech population
Published in Journal of molecular medicine (Berlin, Germany) (01-04-2001)“…Low-density lipoprotein receptor related protein (LRP) is a multifunctional endocytic receptor involved in various biological processes including the…”
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The Relationship Among Apolipoprotein(a) Polymorphisms, the Low-Density Lipoprotein Receptor-Related Protein, and the Very Low Density Lipoprotein Receptor Genes, and Plasma Lipoprotein(A) Concentration in the Czech Population
Published in Human biology (01-02-2002)“…Increased plasma concentration of lipoprotein(a) [Lp(a)] is an established independent risk factor for coronary artery disease (CAD), which is strongly…”
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The role of the IKAP gene polymorphisms in atopic diseases in the middle European population
Published in Journal of human genetics (01-01-2003)“…Over ten genome-wide screens and many candidate genes studies were performed worldwide to elucidate genetic factors involved in the pathogenesis of bronchial…”
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Lack of an association of a single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene in Czech women with pregnancy-induced hypertension
Published in Gynecologic and obstetric investigation (01-01-2001)“…In preeclampsia the cytotrophoblast invasion of the decidual vessels is reduced. The endothelia in the decidual vessels may influence cytotrophoblast invasion…”
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Duration of non-Insulin-dependent diabetes mellitus and the TNF-beta NcoI genotype as predictive factors in proliferative diabetic retinopathy
Published in Ophthalmologica (Basel) (01-07-2001)“…The object of the study was to investigate the share of the polymorphisms I/D ACE, endothelin 1 4127G/A and TNF-beta NcoI in the susceptibility to…”
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Association of two angiotensinogen gene polymorphisms, M235T and G(–6)A, with chronic heart failure
Published in International journal of cardiology (01-06-2003)“…The aim of the study was to focus on the relationship between the angiotensinogen (AGT) gene polymorphisms, M235T and promoter G(–6)A, and chronic heart…”
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Analysis of the Interleukin‐6 Gene Promoter Polymorphisms in Czech Patients with Chronic Periodontitis
Published in Journal of periodontology (1970) (01-01-2004)“…Background: Chronic periodontitis is an inflammatory disease, which is a major cause of tooth loss. The proinflammatory cytokines interleukin‐1 (IL‐1) and…”
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Genetic Variations in the Human Gelatinase A (Matrix Metalloproteinase‐2) Promoter Are Not Associated With Susceptibility to, and Severity of, Chronic Periodontitis
Published in Journal of periodontology (1970) (01-07-2005)“…Background: Gelatinase A (matrix metalloproteinase‐2 [MMP‐2]) has been shown to play an important role in the pathogenesis of several disorders, including…”
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A haplotype constituted of four MMP-2 promoter polymorphisms (−1575G/A, −1306C/T, −790T/G and −735C/T) is associated with coronary triple-vessel disease
Published in Matrix biology (2004)“…Vascular lesion development is associated with an accumulation of extracellular matrix proteins within the vessel wall. The proteins are degraded by matrix…”
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Polymorphisms 1704G/T and 2184A/G in the RAGE gene are associated with antioxidant status
Published in Metabolism, clinical and experimental (01-10-2001)“…The formation of advanced glycation end products (AGEs) and oxidative stress are supposed to play an important role in the development of diabetic late…”
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Polymorphisms in the RAGE gene influence susceptibility to diabetes-associated microvascular dermatoses in NIDDM
Published in Journal of diabetes and its complications (01-07-2001)“…To examine genetic polymorphism in the complete sequence of the Receptor of Advanced Glycation End products (RAGE) gene and its possible associations with…”
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The relationship among apolipoprotein
Published in Human biology (01-02-2002)“…Increased plasma concentration of lipoprotein(a) [Lp(a)] is an established independent risk factor for coronary artery disease (CAD), which is strongly…”
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Association of three polymorphisms in the gene coding for endothelin-1 with essential hypertension, overweight and smoking
Published in Experimental and clinical cardiology (2002)“…To evaluate the association of three endothelin-1 (ET-1) gene polymorphisms with essential hypertension, as well as with two cardiovascular risk factors: body…”
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C766T low-density lipoprotein receptor-related protein 1 (LRP1) gene polymorphism and susceptibility to breast cancer
Published in Breast cancer research : BCR (01-01-2003)“…Low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional endocytic receptor with an important role in regulating the activity of…”
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Methylenetetrahydrofolate Reductase Polymorphism, Type II Diabetes Mellitus, Coronary Artery Disease, and Essential Hypertension in the Czech Population
Published in Molecular genetics and metabolism (01-06-2001)“…Increased plasma concentrations of homocysteine have been found in patients with coronary artery disease (CAD) and essential hypertension (EH) and in patients…”
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Association of 3 gene polymorphisms with atopic diseases
Published in Journal of allergy and clinical immunology (01-04-1999)“…Background: Various peptidases, including angiotensin-converting enzyme (ACE), inactivate some inflammatory peptides that are considered to influence the…”
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