Search Results - "VACCHER, Claude"

Design of experiments for enantiomeric separation in supercritical fluid chromatography by Landagaray, Elodie, Vaccher, Claude, Yous, Saïd, Lipka, Emmanuelle

“…[Display omitted] •Combined effect of ethanol percentage, pressure and flow-rate is studied in SFC.•Design of experiments is implemented to determine optimal…”
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A chemometric approach to elucidate the parameter impact in the hyphenation of evaporative light scattering detector to supercritical fluid chromatography by Lecoeur, Marie, Simon, Nicolas, Sautou, Valérie, Decaudin, Bertrand, Vaccher, Claude

“…•The configuration of the hyphenation setup between SFC and ELSD was optimized.•A multivariate approach was used to elucidate both SFC and ELSD parameters…”
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P-glycoprotein and cytochrome P450 3A4 involvement in risperidone transport using an in vitro Caco-2/TC7 model and an in vivo model by Cousein, Etienne, Barthélémy, Christine, Poullain, Stéphanie, Simon, Nicolas, Lestavel, Sophie, Williame, Virginie, Joiris, Etienne, Danel, Cécile, Clavey, Véronique, Brossard, Denis, Robert, Hugues, Crauste-Manciet, Sylvie, Vaccher, Claude, Odou, Pascal

“…The possible involvement of P-glycoprotein (P-gp) and cytochrome P450 (CYP) 3A4 in risperidone transport was investigated using in vitro and in vivo models…”
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Enantiomeric analysis of baclofen analogs by capillary zone electrophoresis, using highly sulfated cyclodextrins: Inclusion ionization constant pKa determination by Vaccher, Marie-Pierre, Lipka, Emmanuelle, Bonte, Jean-Paul, Foulon, Catherine, Goossens, Jean-François, Vaccher, Claude

“…Using cyclodextrin‐capillary zone electrophoresis (CD‐CZE), baseline separation of baclofen phaclofen, saclofen, and hydroxy‐saclofen, potent γ‐aminobutyric…”
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Analysis of non-phthalates plasticizers on porous graphitic carbon by supercritical fluid chromatography using evaporative light scattering detection by Vaccher, Claude, Decaudin, Bertrand, Sautou, Valérie, Lecoeur, Marie

“…•Non-phthalate plasticizers have been analyzed by SFC/ELSD using porous graphitic carbon.•The effect of various solvents on the ELSD detection of plasticizers…”
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Exploring chiral separation of 3-carboxamido-5-aryl isoxazole derivatives by supercritical fluid chromatography on amylose and cellulose tris dimethyl- and chloromethyl phenylcarbamate polysaccharide based stationary phases by Zehani, Yasmine, Lemaire, Lucas, Ghinet, Alina, Millet, Régis, Chavatte, Philippe, Vaccher, Claude, Lipka, Emmanuelle

“…•Chiral ligands of the CB2 receptors.•Comparison of chloromethylated and dimethylated CSPs for separation.•Study of the effect of type and percentage, of…”
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Analysis of PVC plasticizers in medical devices and infused solutions by GC-MS by Bourdeaux, Daniel, Yessaad, Mouloud, Chennell, Philip, Larbre, Virginie, Eljezi, Teuta, Bernard, Lise, Sautou, Valerie

“…In 2008, di-(2-ethylhexyl) phthalate (DEHP), was categorized as CMR 1B under the CLP regulations and its use in PVC medical devices (MD) was called into…”
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Enhanced detection for determination of enantiomeric purity of novel agomelatine analogs by EKC using single and dual cyclodextrin systems by Lipka, Emmanuelle, Landagaray, Elodie, Ettaoussi, Mohamed, Yous, Saïd, Vaccher, Claude

“…Performing CD‐EKC, baseline separation of five agomelatine analogs, potential antidepressant compounds, was achieved. A method for the enantioresolution and…”
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Development of HPLC/fluorescence detection method for chiral resolution of dansylated benzimidazoles derivatives by Lipka, Emmanuelle, Charton, Julie, Vaccher, Claude

“…ABSTRACT The development of high performance liquid chromatography method on amylose‐based stationary phase (Chiralpak AD) with n‐hexane–2‐propanol (90:10,…”
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3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies by Berthelot, Pascal, Vaccher, Claude, Flouquet, Nathalie, Debaert, Michel, Luyckx, Michel, Brunet, Claude

“…Baclofen (beta-(p-chlorophenyl)-GABA) is a selective agonist for the bicuculline-insensitive GABAB receptor. The search for new compounds that bind to the…”
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Quantitative analysis of drugs in biological matrices by HPLC hyphenated to fluorescence detection by Lipka, Emmanuelle, Vaccher, Claude

“…An overview of the state-of-the art in HPLC coupled with fluorescence detection is presented. Over the last 20 years, the increasing number of methodological…”
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Enantioseparation and thermodynamic study of naphthalene derivatives, new melatoninergic agonists, on coated amylose [tris(S)-1-phenylethylcarbamate] stationary phase. Transposition to preparative scale by Landagaray, Elodie, Yous, Saïd, Vaccher, Claude, Lipka, Emmanuelle

“…This work reports a high‐performance liquid chromatography normal‐phase methodology to elucidate enantiomers of naphthalene derivatives, evaluated as…”
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Comparison of high-performance liquid chromatography and supercritical fluid chromatography using evaporative light scattering detection for the determination of plasticizers in medical devices by Lecoeur, Marie, Decaudin, Bertrand, Guillotin, Yoann, Sautou, Valérie, Vaccher, Claude

“…•Quantitative SFC/ELSD performances were evaluated for the analysis of plasticizers.•SFC/ELSD performances were compared with a reference method…”
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Enantioseparation of pyroglutamide derivatives on polysaccharide based chiral stationary phases by high-performance liquid chromatography and supercritical fluid chromatography: A comparative study by Baudelet, Davy, Schifano-Faux, Nadège, Ghinet, Alina, Dezitter, Xavier, Barbotin, Florent, Gautret, Philippe, Rigo, Benoit, Chavatte, Philippe, Millet, Régis, Furman, Christophe, Vaccher, Claude, Lipka, Emmanuelle

“…•Pyroglutamide derivatives known as h-P2X7 receptor antagonists.•Enantioseparation on polysaccharide based chiral stationary phases.•Comparative study of…”
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Study of the complexation of risperidone and 9-hydroxyrisperidone with cyclodextrin hosts using affinity capillary electrophoresis and (1)H NMR spectroscopy by Danel, Cécile, Azaroual, Nathalie, Brunel, Albane, Lannoy, Damien, Vermeersch, Gaston, Odou, Pascal, Vaccher, Claude

“…The complexation of risperidone (Risp) and 9-hydroxyrisperidone (9-OH-Risp), atypical antipsychotics, with seven cyclodextrins (CDs) of pharmaceutical interest…”
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A validated micellar electrokinetic chromatography method for the quantitation of dexamethasone, ondansetron and aprepitant, antiemetic drugs, in organogel by Bourdon, Florence, Lecoeur, Marie, Duhaut, Marion, Odou, Pascal, Vaccher, Claude, Foulon, Catherine

“…•A MEKC/UV method was developed for the simultaneous determination of ondansetron, dexamethasone and aprepitant.•Central composite statistical design was used…”
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Antagonists of the P2X7 receptor: Mechanism of enantioselective recognition using highly sulfated and sulfobutylether cyclodextrins by capillary electrokinetic chromatography by Baudelet, Davy, Ghinet, Alina, Furman, Christophe, Dezitter, Xavier, Gautret, Philippe, Rigo, Benoit, Millet, Régis, Vaccher, Claude, Lipka, Emmanuelle

“…This work concerns the successful enantiomeric separation of pyroglutamic acid derivatives, known to be P2X7 receptor antagonists, achieved by electrokinetic…”
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Corrigendum to “Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor” [J. Chromatogr. B 986–987 (2015) 35–43] by Baudelet, Davy, Furman, Christophe, Ghinet, Alina, Dezitter, Xavier, Adriouch, Sahil, Capet, Frédéric, Rogez-Florent, Tiphaine, Gautret, Philippe, Rigo, Benoit, Millet, Régis, Vaccher, Claude, Lipka, Emmanuelle

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Quantification of five plasticizers used in PVC tubing through high performance liquid chromatographic-UV detection by Radaniel, Tsanta, Genay, Stéphanie, Simon, Nicolas, Feutry, Frédéric, Quagliozzi, Francesca, Barthélémy, Christine, Lecoeur, Marie, Sautou, Valérie, Décaudin, Bertrand, Odou, Pascal

“…•The development of a rapid and simple technique for 4 DEHP-substitute plasticizers.•The ability to measure the DINCH by HPLC–UV with other plasticizers.•The…”
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Evaluation of three neutral capillary coatings for the determination of analyte-cyclodextrin binding constants by affinity capillary electrophoresis. Application to N,N⿲-disubstituted piperazine derivatives by Danel, Cécile, Melnyk, Patricia, Azaroual, Nathalie, Larchanché, Paul-Emmanuel, Goossens, Jean-François, Vaccher, Claude

“…⿢Three neutral coatings are evaluated to avoid the analyte and CD adsorption.⿢CD adsorption on the HPC and PEO coatings is proved.⿢PDMA coating allows to…”
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