Search Results - "V. Tverdokhlebov, Anton"

The homologous tert-amino effect: a route to fused 2-benzazepine derivatives by Gorulya, Alexander P., Tverdokhlebov, Anton V., Tolmachev, Andrey A., Shishkin, Oleg V., Shishkina, Svetlana V.

“…2-Cyano- and 2-carbethoxy-3-[2-(pyrrolidin-1-ylmethyl)phenyl]acrylonitriles were prepared through either amination of appropriate…”
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Synthesis of 3-(Pyrimidinyl)pyrrole Derivatives by V. Tverdokhlebov, Anton, Yu. Nestorak, Igor, A. Tolmachev, Andrey, M. Volovenko, Yulian

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Simple and Convenient Synthesis of 2,3,4,5-Tetrahydro-1,5-dioxopyrrolo[1,2-a]quinazoline- 3a(1H)-carboxylic Acids in Multi-Gram Scale by V. Tverdokhlebov, Anton, T. Iminov, Rustam, A. Tolmachev, Andrey, M. Volovenko, Yulian, N. Kostyuk, Alexander, N. Chernega, Alexander, B. Rusanov, Eduard

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Preparation of 5-Amino-1,2-dihydro-4-(1-methyl-4-piperidinyl)pyrrol-3-ones by V. Tverdokhlebov, Anton, A. Chalyk, Bohdan, T. Iminov, Rustam, A. Tolmachev, Andrey

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Multigram Synthesis of Fluoroalkyl-Substituted Pyrazole-4-carboxylic Acids by Iminov, Rustam T., Mashkov, Alexander V., Vyzir, Ivan I., Chalyk, Bohdan A., Tverdokhlebov, Anton V., Mykhailiuk, Pavel K., Babichenko, Ludmila N., Tolmachev, Andrey A., Volovenko, Yulian M., Biitseva, Angelina, Shishkin, Oleg V., Shishkina, Svetlana V.

“…Acylation of tert‐butyl 3‐(methylamino)but‐2‐enoate with fluorinated acetic acid anhydrides occurred at the enamine carbon atom. The reaction of the resulting…”
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Synthesis of fluorinated oxazoles by oxidative cyclization of fluorinated enamides by Shishlyk, Oleg S., Shcherbatiuk, Andrey V., Iminov, Rustam T., Tverdokhlebov, Anton V., Tolmachev, Andrey A., Mykhailiuk, Pavel K., Biitseva, Angelina V.

“…[Display omitted] •Fluorinated isoxazoles were obtained by oxidation of the corresponding enamides.•These fluorinated building blocks are useful for Drug…”
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A Convenient Route to 1-Alkyl-5-trifluoromethyl-1,2,3-triazole-4-carboxylic Acids Employing a Diazo Transfer Reaction by Iminov, Rustam T., Mashkov, Alexander V., Chalyk, Bohdan A., Mykhailiuk, Pavel K., Tverdokhlebov, Anton V., Tolmachev, Andrey A., Volovenko, Yulian M., Shishkin, Oleg V., Shishkina, Svetlana V.

“…The reaction of ethyl 3‐(alkylamino)‐4,4,4‐trifluoro‐but‐2‐enoates with mesyl azide in the presence of 1,8‐diazabicyclo[5.4.0]undec‐7‐ene (DBU) gave ethyl…”
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Pyrrolo[2,1-b]thiazoles by V. Tverdokhlebov, Anton

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Synthesis of condensed tetrahydroimidazo[1,2-a]quinazoline-1,5-dione derivatives by Iminov, Rustam T., Tverdokhlebov, Anton V., Tolmachev, Andrey A., Volovenko, Yulian M., Shishkina, Svetlana V., Shishkin, Oleg. V.

“…Heating of N-{2-[(R-amino)carbonyl]phenyl}prolinamides in triethyl orthoformate solution was found to give…”
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Synthesis of pyrrolo[2,3- c]2,7-naphthyridine derivatives by cascade heterocyclization reaction of 2-amino-4-cyanomethyl-6-dialkylamino-3,5-pyridinedicarbonitriles by Tverdokhlebov, Anton V, Resnyanska, Elizaveta V, Zavada, Alexander V, Tolmachev, Andrey A, Kostyuk, Alexander N, Chernega, Alexander N

“…Alkylation of the title pyridinedicarbonitriles with N-substituted chloroacetamides was found to give 5,6-diamino-8-dialkylamino-2,3-dihydro-2-oxo-1…”
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A New and Convenient Synthesis of 1,2-Diamino-3-hetarylpyrrole Derivatives by Volovenko, Yulian M., Tverdokhlebov, Anton V., Gorulya, Alexandr P., Shishkina, Svetlana V., Zubatyuk, Roman I., Shishkin, Oleg V.

“…A number of 1‐acylamino‐2‐amino‐3‐hetaryl‐4‐oxo‐2‐pyrrolines 13−50 were prepared by treatment of 4‐chloro‐2‐hetaryl‐3‐oxobutanenitriles 11a−h with substituted…”
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An Interaction of 2-Thiazoleacetonitriles with N-(2-Chloroacetyl)anthranilic Acid Ester by V. Tverdokhlebov, Anton, V. Resnyanska, Elizaveta, A. Tolmachev, Andrey, M. Volovenko, Yulian, V. Shokol, Tatyana

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Synthesis of masked 2-amino-6-methyl-4-oxo-4H-pyran-3-carbaldehydes by Denisenko, Alexander, Tverdokhlebov, Anton

“…Acetoacetylation of (1,3-dimethylbenzimidazol-2-ylidene)-, (3-methylbenzothiazol-2-ylidene)-, and (3,4-dimethylthiazol-2-ylidene)acetonitriles with…”
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Synthesis of structurally constrained 4-quinazolinone derivatives with a tetrahedral C-2 atom present in three rings by Iminov, Rustam T., Tverdokhlebov, Anton V., Tolmachev, Andrey A., Volovenko, Yulian M., Shishkina, Svetlana V., Shishkin, Oleg V.

“…The reaction of 2-aminobenzamides with 2-oxocyclopentane-, 2-oxocyclohexane-, and 2-oxocycloheptaneacetic acids esters was found to give…”
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A novel tert-amino effect based approach to 1,2,3,4-tetrahydroquinoline-2-spirocycloalkanes by Tverdokhlebov, Anton V., Gorulya, Alexander P., Tolmachev, Andrey A., Kostyuk, Alexander N., Chernega, Alexander N., Rusanov, Eduard B.

“…An interaction of 2-[cyclohexyl(methyl)amino]benzaldehydes with substituted acetonitriles X-CH 2CN (X=CN, Tos, hetaryl) was found to yield…”
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2-Benzothiazolemethanol as Precursor of 2-Aryl-1-(2-benzothiazolyl)-1-ethanones by Ryabukhin, Sergey V., Plaskon, Andrey S., Tverdokhlebov, Anton V., Tolmachev, Andrey A.

“…2-Benzothiazolemethanol was found to react with substituted benzaldehydes in the presence of excess chlorotrimethylsilane yielding the title ketones after…”
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Synthesis of furo[2,3- c]-2,7-naphthyridine derivatives via domino heterocyclization reaction by Tverdokhlebov, Anton V., Zavada, Alexander V., Tolmachev, Andrey A., Kostyuk, Alexander N., Chernega, Alexander N., Rusanov, Eduard B.

“…2-Amino-4-cyanomethyl-6-dialkylamino-3,5-pyridinedicarbonitriles were found to react with substituted oxiranes yielding…”
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Synthesis of Pyrrolo[2,1-b]thiazol-3-one Derivatives by Tverdokhlebov, Anton V., Andrushko, Alexander P., Tolmachev, Andrey A., Kostyuk, Alexander N., Chernega, Alexander N., Rusanov, Eduard B.

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Regioselective Heteroannelation in 4-Cyanomethyl-3,5-pyridinedicarbonitriles. Synthesis of 6-Alkoxy-3-dialkylamino-1,8-diamino-2,7-naphthyridine-4-carbonitriles by Tverdokhlebov, Anton V., Resnyanska, Elizaveta V., Tolmachev, Andrey A., Zavada, Alexander V.

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A Facile Route to the 6-Hetaryl Substituted Pyrrolo[1,2-a]thieno[3,2-e]pyrimidine Derivatives by Volovenko, Yulian M., Resnyanska, Elizaveta V., Tverdokhlebov, Anton V.

“…Hitherto unknown 6-hetaryl-4,5,7,8-tetrahydropyrrolo[1,2- a ]thieno[3,2- e ]pyrimidine-4,7-diones ( 7a - 7g ) were prepared by reaction of ethyl…”
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