Search Results - "V. LAUDET"

Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor by Laudet, V

“…From a database containing the published nuclear hormone receptor (NR) sequences I constructed an alignment of the C, D and E domains of these molecules. Using…”
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Principles for modulation of the nuclear receptor superfamily by Laudet, Vincent, Gronemeyer, Hinrich, Gustafsson, Jan-Åke

“…Nuclear receptors are major targets for drug discovery and have key roles in development and homeostasis, as well as in many diseases such as obesity, diabetes…”
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3,5-T2 Is an Alternative Ligand for the Thyroid Hormone Receptor β1 by Mendoza, A, Navarrete-Ramírez, P, Hernández-Puga, G, Villalobos, P, Holzer, G, Renaud, J.P, Laudet, V, Orozco, A

“…Several liganded nuclear receptors have alternative ligands acting in a tissue-specific fashion and playing important biological roles. We present evidence…”
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The chordate amphioxus: an emerging model organism for developmental biology by Holland, L Z, Laudet, V, Schubert, M

“…The cephalochordate amphioxus is the closest living invertebrate relative of the vertebrates. It is vertebrate-like in having a dorsal, hollow nerve cord,…”
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Evidence for two distinct functional glucocorticoid receptors in teleost fish by Bury, NR, Sturm, A, Le Rouzic, P, Lethimonier, C, Ducouret, B, Guiguen, Y, Robinson-Rechavi, M, Laudet, V, Rafestin-Oblin, ME, Prunet, P

“…Using RT-PCR with degenerated primers followed by screening of a rainbow trout (Oncorhynchus mykiss) intestinal cDNA library, we have isolated from the rainbow…”
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The cephalochordate amphioxus: a key to reveal the secrets of nuclear receptor evolution by Lecroisey, Claire, Laudet, Vincent, Schubert, Michael

“…The members of the nuclear receptor (NR) superfamily are transcription factors characterized by a particular mode of function, which is related to the…”
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Annotation of Tribolium nuclear receptors reveals an increase in evolutionary rate of a network controlling the ecdysone cascade by Bonneton, François, Chaumot, Arnaud, Laudet, Vincent

“…The Tribolium genome contains 21 nuclear receptors, representing all of the six known subfamilies. This first complete set for a coleopteran species reveals a…”
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A unified nomenclature system for the nuclear receptor superfamily by Auwerx, J, Baulieu, E, Beato, M, Becker-Andre, M, Burbach, PH, Camerino, G, Chambon, P, Cooney, A, Dejean, A, Dreyer, C, Evans, RM, Gannon, F, Giguere, V, Gronemeyer, H, Gustafson, JA, Laudet, V, Lazar, MA, Mangelsdorf, DJ, Milbrandt, J, Milgrom, E, Moore, DD, O'Malley, B, Parker, M, Parker, K, Perlmann, T, Pfahl, M, Rosenfeld, MG, Samuels, H, Schutz, G, Sladek, FM, Stunnenberg, HG, Spedding, M, Thummel, C, Tsai, MJ, Umesono, K, Vennstrom, B, Wahli, W, Weinberger, C, Willson, TM, Yamamoto, K

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Evolution of Nuclear Retinoic Acid Receptor Alpha (RARα) Phosphorylation Sites. Serine Gain Provides Fine-Tuned Regulation by Samarut, Eric, Amal, Ismail, Markov, Gabriel V., Stote, Roland, Dejaegere, Annick, Laudet, Vincent, Rochette-Egly, Cécile

“…The human nuclear retinoic acid (RA) receptor alpha (hRARα) is a ligand-dependent transcriptional regulator, which is controlled by a phosphorylation cascade…”
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Structural and Evolutionary Innovation of the Heterodimerization Interface between USP and the Ecdysone Receptor ECR in Insects by Iwema, Thomas, Chaumot, Arnaud, Studer, Romain A., Robinson-Rechavi, Marc, Billas, Isabelle M.L., Moras, Dino, Laudet, Vincent, Bonneton, François

“…Understanding how the variability of protein structure arises during evolution and leads to new structure-function relationships ultimately promoting…”
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Characterization of oestrogen receptors in zebrafish (Danio rerio) by Bardet, PL, Horard, B, Robinson-Rechavi, M, Laudet, V, Vanacker, JM

“…We cloned the cDNAs corresponding to three oestrogen receptors (ERs) in zebrafish (Danio rerio). Sequence analysis and phylogenetic studies demonstrated that…”
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A conserved retinoid X receptor (RXR) from the mollusk Biomphalaria glabrata transactivates transcription in the presence of retinoids by Bouton, D, Escriva, H, de Mendonça, R L, Glineur, C, Bertin, B, Noël, C, Robinson-Rechavi, M, de Groot, A, Cornette, J, Laudet, V, Pierce, R J

“…Retinoid X receptors (RXR) are members of the nuclear receptor superfamily of ligand-activated transcription factors that have been characterized in a wide…”
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Phylogenetic dating and characterization of gene duplications in vertebrates: the cartilaginous fish reference by Robinson-Rechavi, Marc, Boussau, Bastien, Laudet, Vincent

“…Vertebrates originated in the lower Cambrian. Their diversification and morphological innovations have been attributed to large-scale gene or genome…”
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Evolution of the nuclear receptor gene superfamily by Laudet, V, Hanni, C, Coll, J, Catzeflis, F, Stehelin, D

“…Nuclear receptor genes represent a large family of genes encoding receptors for various hydrophobic ligands such as steroids, vitamin D, retinoic acid and…”
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rapid divergence of the ecdysone receptor is a synapomorphy for Mecopterida that clarifies the Strepsiptera problem by Bonneton, F, Brunet, F.G, Kathirithamby, J, Laudet, V

“…In arthropods, the regulation by ecdysteroids is mediated by the heterodimer between the ecdysone receptor (ECR; NR1H1) and ultraspiracle (USP/RXR; NR2B4)…”
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Molecular cloning and characterization of thyroid hormone receptors in teleost fish by Marchand, O, Safi, R, Escriva, H, Van Rompaey, E, Prunet, P, Laudet, V

“…Thyroid hormones are pleiotropic factors important for many developmental and physiological functions in vertebrates. Their effects are mediated by two…”
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The Transcriptional Repressor STRA13 Regulates a Subset of Peripheral Circadian Outputs by Gréchez-Cassiau, Aline, Panda, Satchidananda, Lacoche, Samuel, Teboul, Michèle, Azmi, Sameena, Laudet, Vincent, Hogenesch, John B., Taneja, Reshma, Delaunay, Franck

“…Central and peripheral mammalian circadian clocks regulate a variety of behavioral and physiological processes through the rhythmic transcription of hundreds…”
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Ancient DNA analysis reveals woolly rhino evolutionary relationships by Orlando, Ludovic, Leonard, Jennifer A., Thenot, Aurélie, Laudet, Vincent, Guerin, Claude, Hänni, Catherine

“…With ancient DNA technology, DNA sequences have been added to the list of characters available to infer the phyletic position of extinct species in…”
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The orphan COUP-TF nuclear receptors are markers for neurogenesis from cnidarians to vertebrates by Gauchat, Dominique, Escriva, Hector, Miljkovic-Licina, Marijana, Chera, Simona, Langlois, Marie-Claire, Begue, Agnès, Laudet, Vincent, Galliot, Brigitte

“…In bilaterians, COUP-TF nuclear receptors participate in neurogenesis and/or CNS patterning. In hydra, the nervous system is formed of sensory mechanoreceptor…”
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Dimerization is required for transactivation by estrogen-receptor-related (ERR) orphan receptors: evidence from amphioxus ERR by Horard, B, Castet, A, Bardet, P-L, Laudet, V, Cavailles, V, Vanacker, J-M

“…The estrogen-receptor-related (ERR) receptors are orphan members of the nuclear receptor superfamily that bind to their specific DNA target sites as…”
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