Search Results - "Völkel, Tina"
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Targeting of immunoliposomes to endothelial cells using a single-chain Fv fragment directed against human endoglin (CD105)
Published in Biochimica et biophysica acta. Biomembranes (01-05-2004)“…We generated immunoliposomes targeting proliferating endothelial cells by chemically coupling a single-chain Fv fragment (scFv A5) directed against human…”
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2
Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells
Published in Protein engineering, design and selection (01-05-2004)“…RGD peptides targeting αv-integrins are promising ligands for the generation of vascular targeting agents. We isolated from phage display RGD motif libraries…”
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Optimized linker sequences for the expression of monomeric and dimeric bispecific single-chain diabodies
Published in Protein engineering (01-10-2001)“…Bispecific single-chain diabodies (scDb) consist of the variable heavy and light chain domains of two antibodies connected by three linkers. The structure of…”
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Isolation from phage display libraries of lysine‐deficient human epidermal growth factor variants for directional conjugation as targeting ligands
Published in Protein engineering (01-12-2003)“…Ligand‐targeted anticancer therapeutics represent an opportunity for the selective and efficient delivery of drugs to tumours. The chemical coupling of ligands…”
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5
Targeting of immunoliposomes to endothelial cells using a single-chain Fv fragment directed against human endoglin (CD105)
Published in Biochimica et biophysica acta (27-05-2004)“…We generated immunoliposomes targeting proliferating endothelial cells by chemically coupling a single-chain Fv fragment (scFv A5) directed against human…”
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Recombinant bispecific antibodies for the targeting of adenoviruses to CEA-expressing tumour cells: a comparative analysis of bacterially expressed single-chain diabody and tandem scFv
Published in The journal of gene medicine (01-06-2004)“…We have generated two distinct recombinant bispecific antibody molecules for the retargeting of adenoviral vectors to CEA‐expressing tumour cells. These…”
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Production of recombinant bispecific antibodies
Published in Methods in molecular biology (Clifton, N.J.) (2004)Get more information
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Isolation of endothelial cell-specific human antibodies from a novel fully synthetic scFv library
Published in Biochemical and biophysical research communications (30-04-2004)“…We have isolated single-chain Fv fragments directed against human endothelial cells from a novel fully synthetic human scFv library (scFv 479). This library…”
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Engineering of human coagulation factor x variants activated by prostate-specific antigen
Published in Molecular biotechnology (01-01-2005)“…In this study, we present a novel approach for the induction of tumor vessel thrombosis using genetically modified coagulation factor X. Human factor X was…”
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