Search Results - "Véret, Julien"

Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets by Bellini, Lara, Campana, Mélanie, Rouch, Claude, Chacinska, Marta, Bugliani, Marco, Meneyrol, Kelly, Hainault, Isabelle, Lenoir, Véronique, Denom, Jessica, Véret, Julien, Kassis, Nadim, Thorens, Bernard, Ibberson, Mark, Marchetti, Piero, Blachnio-Zabielska, Agnieszka, Cruciani-Guglielmacci, Céline, Prip-Buus, Carina, Magnan, Christophe, Le Stunff, Hervé

“…Aims/hypothesis Dietary n -3 polyunsaturated fatty acids, especially docosahexaenoic acid (DHA), are known to influence glucose homeostasis. We recently showed…”
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Ceramide Transporter CERT Is Involved in Muscle Insulin Signaling Defects Under Lipotoxic Conditions by Bandet, Cécile L, Mahfouz, Rana, Véret, Julien, Sotiropoulos, Athanassia, Poirier, Maxime, Giussani, Paola, Campana, Mélanie, Philippe, Erwann, Blachnio-Zabielska, Agnieszka, Ballaire, Raphaëlle, Le Liepvre, Xavier, Bourron, Olivier, Berkeš, Dušan, Górski, Jan, Ferré, Pascal, Le Stunff, Hervé, Foufelle, Fabienne, Hajduch, Eric

“…One main mechanism of insulin resistance (IR), a key feature of type 2 diabetes, is the accumulation of saturated fatty acids (FAs) in the muscles of obese…”
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Deciphering the Link Between Hyperhomocysteinemia and Ceramide Metabolism in Alzheimer-Type Neurodegeneration by Le Stunff, Hervé, Véret, Julien, Kassis, Nadim, Denom, Jessica, Meneyrol, Kelly, Paul, Jean-Louis, Cruciani-Guglielmacci, Céline, Magnan, Christophe, Janel, Nathalie

“…Aging is one of the strongest risk factor for Alzheimer's disease (AD). However, several data suggest that dyslipidemia can either contribute or serve as…”
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Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes by Bellini, Lara, Campana, Mélanie, Mahfouz, Rana, Carlier, Aurélie, Véret, Julien, Magnan, Christophe, Hajduch, Eric, Le Stunff, Hervé

“…Obesity is a major factor that is linked to the development of type 2 diabetes (T2D). Excess circulating fatty acids (FAs), which characterize obesity, induce…”
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Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells by Véret, Julien, Coant, Nicolas, Berdyshev, Evgeny V, Skobeleva, Anastasia, Therville, Nicole, Bailbé, Danielle, Gorshkova, Irina, Natarajan, Viswanathan, Portha, Bernard, Le Stunff, Hervé

“…Pancreatic β-cell apoptosis induced by palmitate requires high glucose concentrations. Ceramides have been suggested to be important mediators of…”
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Roles of Sphingolipid Metabolism in Pancreatic β Cell Dysfunction Induced by Lipotoxicity by Véret, Julien, Bellini, Lara, Giussani, Paola, Ng, Carl, Magnan, Christophe, Le Stunff, Hervé

“…Pancreatic β cells secrete insulin in order to maintain glucose homeostasis. However, various environmental stresses such as obesity have been shown to induce…”
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Rôle de la sphingosine kinase 1 dans l’apoptose des cellules β pancréatiques induite par la glucolipotoxicité by Le Marec, Axelle, Chérif, Mikael, Véret, Julien, Courty, Emilie, Kassis, Nadim, Magnan, Christophe, Blondeau, Bertrand, Le Stunff, Hervé

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Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 β-cell survival by Véret, Julien, Coant, Nicolas, Gorshkova, Irina A., Giussani, Paola, Fradet, Magali, Riccitelli, Elena, Skobeleva, Anastasia, Goya, Jonathan, Kassis, Nadim, Natarajan, Viswanathan, Portha, Bernard, Berdyshev, Evgeny V., Le Stunff, Hervé

“…Sphingoid base-1-phosphates represent a very low portion of the sphingolipid pool but are potent bioactive lipids in mammals. This study was undertaken to…”
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CO-9 - Rôle de la sphingosine kinase 1 dans l’apoptose des cellules β pancréatiques induite par la glucolipotoxicité by Le Marec, Axelle, Chérif, Mikael, Véret, Julien, Courty, Emilie, Kassis, Nadim, Magnan, Christophe, Blondeau, Bertrand, Le Stunff, Hervé

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Role of the sphingolipid biostat in pancreatic βcell apoptosis induced by gluco‐lipotoxicity by COANT, Nicolas, Veret, Julien, Giussani, Paola, Portha, Bernard, Berdyshev, Evgeny V, Le Stunff, Herve

“…Abstract only Accumulated evidence suggests that Type 2 diabetes is often associated with abnormalities in lipids metabolism. Adverse effects of fatty acids on…”
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