Search Results - "Vély, F"

NK cell compartment in the peripheral blood and spleen in adult patients with primary immune thrombocytopenia by Ebbo, M, Audonnet, S, Grados, A, Benarous, L, Mahevas, M, Godeau, B, Viallard, J.F, Piperoglou, C, Cognet, C, Farnarier, C, Harlé, J.R, Schleinitz, N, Vély, F

“…Abstract Immune thrombocytopenic purpura (ITP) is a disease characterized by antibody-mediated platelet destruction. The T- and B-cell subsets have been…”
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Conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/activatory counterparts by Vély, F, Vivier, E

“…Immunoreceptor tyrosine-based inhibition motifs (ITIMs) consist of a 6-amino acid stretch (ILV)xYxx(LV). ITIMs are expressed in the intracytoplasmic domain of…”
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IgG4-related systemic disease: emergence of a new systemic disease? Literature review by Ebbo, M, Grados, A, Daniel, L, Vély, F, Harlé, J-R, Pavic, M, Schleinitz, N

“…Hyper-IgG4 syndrome, or IgG4-related systemic disease (IgG4-RSD), has been recently characterized by the association of a focal or diffuse enlargement in one…”
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Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases by Olcese, L, Lang, P, Vely, F, Cambiaggi, A, Marguet, D, Blery, M, Hippen, KL, Biassoni, R, Moretta, A, Moretta, L, Cambier, JC, Vivier, E

“…NK cells express cell surface receptors for MHC class I proteins (KIR). Engagement of these receptors inhibits NK cell cytotoxic programs. KIR can be expressed…”
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Signaling pathways engaged by NK cell receptors: double concerto for activating receptors, inhibitory receptors and NK cells by Tomasello, Elena, Blery, Mathieu, Vely, Eric, Vivier, Eric

“…Despite the absence of antigen-specific receptors at their surface, NK cells can selectively eliminate virus-infected cells, tumor cells and allogenic cells. A…”
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Inhibition of antigen‐induced T cell response and antibody‐induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP‐1 and SHP‐2 protein‐tyrosine phosphatases by Le Dréan, Eric, Vély, Frédéric, Olcese, Lucia, Cambiaggi, Anna, Guia, Sophie, Krystal, Gerald, Gervois, Nadine, Moretta, Alessandro, Jotereau, Francine, Vivier, Eric

“…Subsets of T and natural killer (NK) lymphocytes express the CD94‐NKG2A heterodimer, a receptor for major histocompatibility complex class I molecules. We show…”
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The Paired Ig-Like Receptor PIR-B is an Inhibitory Receptor that Recruits the Protein-Tyrosine Phosphatase SHP-1 by Blery, Mathieu, Kubagawa, Hiromi, Chen, Ching-Cheng, Vely, Frederic, Cooper, Max D., Vivier, Eric

“…An emerging family of cell surface inhibitory receptors is characterized by the presence of intracytoplasmic immunoreceptor tyrosine-based inhibition motifs…”
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Gene Structure, Expression Pattern, and Biological Activity of Mouse Killer Cell Activating Receptor-associated Protein (KARAP)/DAP-12 by Tomasello, E, Olcese, L, Vély, F, Geourgeon, C, Bléry, M, Moqrich, A, Gautheret, D, Djabali, M, Mattei, M G, Vivier, E

“…Natural killer cell and T cell subsets express at their cell surface a repertoire of receptors for MHC class I molecules, the natural killer cell receptors…”
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Transduction of cytotoxic signals in natural killer cells: a general model of fine tuning between activatory and inhibitory pathways in lymphocytes by Renard, Valéry, Cambiaggi, Anna, Vély, Frederic, Bléry, Mathieu, Olcese, Lucia, Olivero, Sylvain, Bouchet, Magali, Vivier, Eric

“…NK‐cells axe large granular lymphocytes, which are capable of exerting two major types of effector function, cell cytotoxicity and lymphokine secretion. NK…”
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Association of signal‐regulatory proteins β  with KARAP/DAP‐12 by Tomasello, Elena, Cant, Charles, Bühring, Hans‐Jörg, Vély, Fréd´eric, André, Pascale, Seiffert, Martine, Ullrich, Axel, Vivier, Eric

“…The signal‐regulatory proteins (SIRP) are Ig‐like cell surface receptors detected in hematopoietic and non‐hematopoietic cells. SIRP are classified as SIRPα…”
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Differential association of phosphatases with hematopoietic co-receptors bearing immunoreceptor tyrosine-based inhibition motifs by Vély, F, Olivero, S, Olcese, L, Moretta, A, Damen, J E, Liu, L, Krystal, G, Cambier, J C, Daëron, M, Vivier, E

“…A novel family of inhibitory co-receptors has been recently defined according to the presence in their intracytoplasmic domain of immunoreceptor tyrosine-based…”
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Recognition of Peptide-MHC Class I Complexes by Activating Killer Immunoglobulin-Like Receptors by Stewart, C. Andrew, Laugier-Anfossi, Fanny, Vély, Frédéric, Saulquin, Xavier, Riedmuller, Jenifer, Tisserant, Agnès, Gauthier, Laurent, Romagné, François, Ferracci, Géraldine, Arosa, Fernando A., Moretta, Alessandro, Sun, Peter D., Ugolini, Sophie, Vivier, Eric, Cresswell, Peter

“…Inhibitory receptors for MHC class I molecules increase the threshold of lymphocyte activation. Natural Killer (NK) cells express a large number of such…”
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Spinal cord toxoplasmosis in a young immunocompetent patient by Martinot, M., Greigert, V., Farnarier, C., Dardé, M. L., Piperoglou, C., Mohseni-Zadeh, M., Tarabeux, J., Guffroy, A., Villard, O., Vely, F.

“…We report a case of spinal cord toxoplasmosis occurring as a primary infection in a 31-year-old immunocompetent man. Exhaustive immunologic and genetic…”
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The enigma of activating isoforms of ITIM-bearing molecules by Cambiaggi, A, Lucas, M, Vivier, E, Vély, F

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Maladie systémique associée aux IgG4 : une pathologie émergente ? Mise au point et revue de la littérature by Ebbo, M., Grados, A., Daniel, L., Vély, F., Harlé, J.-R., Pavic, M., Schleinitz, N.

“…Le syndrome d’hyper-IgG4, ou maladie systémique associée aux IgG4, est une entité de description récente caractérisée par la présence d’une ou plusieurs…”
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BIAcore analysis to test phosphopeptide-SH2 domain interactions by Vély, F, Trautmann, A, Vivier, E

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NK cells: new insights on physiology and clinical implication in diseases by Schleinitz, N, Hamidou, M, Vély, F, Paul, P, Figarella-Branger, D, Kaplanski, G, Dignat-George, F, Vivier, E, Harlé, J R

“…Natural killer cells are cytotoxic lymphocytes of innate immunity. These last ten years our knowledge about the mechanisms that regulates NK cell function has…”
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Analysis of immunoreceptor tyrosine-based activation motif (ITAM) binding to ZAP-70 by surface plasmon resonance by Vély, F, Nunès, J A, Malissen, B, Hedgecock, C J

“…The signaling function of the T cell antigen receptor (TCR) is mediated via CD3 polypeptides, the cytoplasmic sequences of which bear conserved immunoreceptor…”
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LBA53 Precision immuno-oncology for advanced non-small cell lung cancer (NSCLC) patients (pts) treated with PD1/L1 immune checkpoint inhibitors (ICIs): A first analysis of the PIONeeR study by Barlesi, F., Greillier, L., Monville, F., Foa, C., J. le Treut, Audigier-Valette, C., Vély, F., Garcia, S., Sabatier, F., Ciccolini, J., Fabre, M., Le Ray, M., Resseguier, N., Outters, P., Roumieux, M., Mazieres, J., Pérol, M., Vivier, E., Auquier, P., Fieschi, J.

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Severe peripheral blood lymphopenia without NK cell cytotoxicty deficiency is the rule in adult acquired HLH by Carvelli, J, Piperoglou, C, Vely, F, Farnarier, C, Mazodier, K, Harle, J-R, Vivier, E, Kaplanski, G

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