Search Results - "Vågbø, C B"

Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication by Boeckemeier, L, Kraehenbuehl, R, Keszthelyi, A, Gasasira, M U, Vernon, E G, Beardmore, R, Vågbø, C B, Chaplin, D, Gollins, S, Krokan, H E, Lambert, S A E, Paizs, B, Hartsuiker, E

“…The Mre11 nuclease is involved in early responses to DNA damage, often mediated by its role in DNA end processing. mutations and aberrant expression are…”
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Variability of coumarin 7- and 3-hydroxylation in a Jordanian population is suggestive of a functional polymorphism in cytochrome P450 CYP2A6 by HADIDI, H, IRSHAID, Y, VAGBØ, C. B, BRUNSVIK, A, CHOLERTON, S, ZAHLSEN, K, IDLE, J. R

“…To determine the variability of coumarin 7- and 3-hydroxylation in a human population and to evaluate the evidence for the existence of genetic polymorphism in…”
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Insights into the mechanisms of ifosfamide encephalopathy: drug metabolites have agonistic effects on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate receptors and induce cellular acidification in mouse cortical neurons by Chatton, J Y, Idle, J R, Vågbø, C B, Magistretti, P J

“…Therapeutic value of the alkylating agent ifosfamide has been limited by major side effects including encephalopathy. Although the underlying biochemical…”
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AlkB demethylases flip out in different ways by Sundheim, Ottar, Talstad, Vivi A., Vågbø, Cathrine Broberg, Slupphaug, Geir, Krokan, Hans E.

“…Aberrant methylations in DNA are repaired by base excision repair (BER) and direct repair by a methyltransferase or by an oxidative demethylase of the AlkB…”
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Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA by Krokan, Hans E, Aas, Per Arne, Otterlei, Marit, Falnes, Pål Ø, Vågbø, Cathrine B, Skorpen, Frank, Akbari, Mansour, Sundheim, Ottar, Bjørås, Magnar, Slupphaug, Geir, Seeberg, Erling

“…Repair of DNA damage is essential for maintaining genome integrity, and repair deficiencies in mammals are associated with cancer, neurological disease and…”
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