Search Results - "Vähätalo, Jyrki"

Biodistribution of boron after intravenous 4-dihydroxyborylphenylalanine-fructose (BPA-F) infusion in meningioma and schwannoma patients: A feasibility study for boron neutron capture therapy by Kulvik, Martti, Kallio, Merja, Laakso, Juha, Vähätalo, Jyrki, Hermans, Raine, Järviluoma, Eija, Paetau, Anders, Rasilainen, Merja, Ruokonen, Inkeri, Seppälä, Matti, Jääskeläinen, Juha

“…We studied the uptake of boron after 100mg/kg BPA infusion in three meningioma and five schwannoma patients as a pre-BNCT feasibility study. With average…”
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Atomic Emission Method for Total Boron in Blood during Neutron-Capture Therapy by Laakso, Juha, Kulvik, Martti, Ruokonen, Inkeri, Vahatalo, Jyrki, Zilliacus, Riitta, Farkkila, Markus, Kallio, Merja

“…Boron neutron-capture therapy (BNCT) is a drug-targeted binary radiotherapy for cancer. The (10)B capture of thermal neutrons induces secondary radiation…”
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Synthesis of 4-dihydroxyboryl-2-[18F]fluorophenylalanine with relatively high-specific activity by Vähätalo, Jyrki K., Eskola, Olli, Bergman, Jörgen, Forsback, Sarita, Lehikoinen, Pertti, Jääskeläinen, Juha, Solin, Olof

“…An alternative procedure to produce 4‐dihydroxyboryl‐2‐[18F]fluorophenylalanine ([18F]FBPA) for positron emission tomography studies in boron neutron capture…”
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Boron neutron capture therapy of brain tumors: clinical trials at the finnish facility using boronophenylalanine by Joensuu, Heikki, Kankaanranta, Leena, Seppälä, Tiina, Auterinen, Iiro, Kallio, Merja, Kulvik, Martti, Laakso, Juha, Vähätalo, Jyrki, Kortesniemi, Mika, Kotiluoto, Petri, Serén, Tom, Karila, Johanna, Brander, Antti, Järviluoma, Eija, Ryynänen, Päiivi, Paetau, Anders, Ruokonen, Inkeri, Minn, Heikki, Tenhunen, Mikko, Jääskeläinen, Juha, Färkkilä, Markus, Savolainen, Sauli

“…Two clinical trials are currently running at the Finnish dedicated boron neutron capture therapy (BNCT) facility. Between May 1999 and December 2001, 18…”
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Uptake of 4-borono-2-[18F]fluoro-L-phenylalanine in sporadic and neurofibromatosis 2-related schwannoma and meningioma studied with PET by Havu-Aurén, Katja, Kiiski, Johanna, Lehtiö, Kaisa, Eskola, Olli, Kulvik, Martti, Vuorinen, Ville, Oikonen, Vesa, Vähätalo, Jyrki, Jääskeläinen, Juha, Minn, Heikki

“…Meningiomas and schwannomas associated with neurofibromatosis 2 (NF2) are difficult to control by microsurgery and stereotactic radiotherapy alone. Boron…”
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Undifferentiated sinonasal carcinoma may respond to single-fraction boron neutron capture therapy by Kouri, Mauri, Kankaanranta, Leena, Seppälä, Tiina, Tervo, Leena, Rasilainen, Merja, Minn, Heikki, Eskola, Olli, Vähätalo, Jyrki, Paetau, Anders, Savolainen, Sauli, Auterinen, Iiro, Jääskeläinen, Juha, Joensuu, Heikki

“…A large, rapidly progressing, unresectable undifferentiated sinonasal head and neck carcinoma regressed rapidly following single fraction boron neutron capture…”
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Clinical implementation of 4-dihydroxyborylphenylalanine synthesised by an asymmetric pathway by Kulvik, Martti, Vähätalo, Jyrki, Buchar, Evzen, Färkkilä, Markus, Järviluoma, Eija, Jääskeläinen, Juha, Křiž, Otomar, Laakso, Juha, Rasilainen, Merja, Ruokonen, Inkeri, Kallio, Merja

“…Boron neutron capture therapy (BNCT) is an experimental therapeutic modality combining a boron pharmaceutical with neutron irradiation…”
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Boron neutron capture therapy of brain tumors: clinical trials at the Finnish facility using boronophenylalanine: Boron neutron capture therapy: A critical assessment by JOENSUU, Heikki, KANKAANRANTA, Leena, SEREN, Tom, KARILA, Johanna, BRANDER, Antti, JÄRVILUOMA, Eija, RYYNÄNEN, Päivi, PAETAU, Anders, RUOKONEN, Inkeri, MINN, Heikki, TENHUNEN, Mikko, JÄÄSKELÄINEN, Juha, SEPPÄLÄ, Tiina, FÄRKKILÄ, Markus, SAVOLAINEN, Sauli, AUTERINEN, Iiro, KALLIO, Merja, KULVIK, Martti, LAAKSO, Juha, VÄHÄTALO, Jyrki, KORTESNIEMI, Mika, KOTILUOTO, Petri

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Trace impurities identified by high performance liquid chromatography/electrospray mass spectrometry in two different synthetic batches of 4-boronophenylalanine by Vähätalo, Jyrki, Tuominen, Jari, Kokkonen, Juha, Kříž, Otomar, Karonen, Sirkka-Liisa, Kallio, Merja

“…The chemical purity of two synthetic 4‐boronophenylalanine (BPA, C9H12O4BN) batches produced by two different pathways were investigated by high performance…”
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