Search Results - "Vázquez‐Roque, Rubén A."
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Curcuma treatment prevents cognitive deficit and alteration of neuronal morphology in the limbic system of aging rats
Published in Synapse (New York, N.Y.) (01-03-2017)“…Curcuma is a natural compound that has shown neuroprotective properties, and has been reported to prevent aging and improve memory. While the mechanism(s)…”
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Exploratory analysis of genetic variants influencing molecular traits in cerebral cortex of suicide completers
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01-01-2020)“…Genetic factors have been implicated in suicidal behavior. It has been suggested that one of the roles of genetic factors in suicide could be represented by…”
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The treatment of Goji berry (Lycium barbarum) improves the neuroplasticity of the prefrontal cortex and hippocampus in aged rats
Published in The Journal of nutritional biochemistry (01-09-2020)“…The main characteristic of brain aging is an exacerbated inflammatory and oxidative response that affects dendritic morphology and the function of the neurons…”
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Mirror neurons and empathy-related regions in psychopathy: Systematic review, meta-analysis, and a working model
Published in Social neuroscience (03-09-2022)“…Mirror neurons have been associated with empathy. People with psychopathic traits present low levels of empathy. To analyze this, a systematic review of fMRI…”
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Metabolic syndrome causes recognition impairments and reduced hippocampal neuronal plasticity in rats
Published in Journal of chemical neuroanatomy (01-07-2017)“…[Display omitted] •Metabolic syndrome is associated with poor recognition memory.•Hypercaloric diet induced reduction in dendritic spines density.•Metabolic…”
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PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function
Published in Science translational medicine (11-07-2012)“…Huntington's disease (HD) is caused by CAG repeat expansions in the huntingtin (htt) gene, yielding proteins containing polyglutamine repeats that become…”
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Brain Gene Expression-DNA Methylation Correlation in Suicide Completers: Preliminary Results
Published in Revista de investigacion clinica (01-09-2020)Get full text
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High-carbohydrate and fat diet consumption causes metabolic deterioration, neuronal damage, and loss of recognition memory in rats
Published in Journal of chemical neuroanatomy (01-04-2023)“…The number of people diagnosed with metabolic syndrome (MetS) has increased dramatically to reach alarming proportions worldwide. The origin of MetS derives…”
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Cerebrolysin improves memory and ameliorates neuronal atrophy in spontaneously hypertensive, aged rats
Published in Synapse (New York, N.Y.) (01-09-2016)“…The spontaneously hypertensive (SH) rat has been used as an animal model of vascular dementia (VD). Our previous report showed that, SH rats exhibited…”
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Differential effects of UCHL1 modulation on alpha-synuclein in PD-like models of alpha-synucleinopathy
Published in PloS one (13-04-2012)“…Parkinson's disease (PD) is a progressive neurodegenerative disorder caused by genetic and environmental factors. Abnormal accumulation and aggregation of…”
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Brain Gene Expression-DNA Methylation Correlation in Suicide Completers: Preliminary Results
Published in Revista de investigacion clinica (07-05-2020)“…Gene expression alterations have been implicated in suicide pathology. However, the study of the regulatory effect of DNA methylation on gene expression in the…”
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