Search Results - "Vázquez‐Borrego, Mari C."

Towards Understanding the Direct and Indirect Actions of Growth Hormone in Controlling Hepatocyte Carbohydrate and Lipid Metabolism by Vázquez-Borrego, Mari C, Del Rio-Moreno, Mercedes, Kineman, Rhonda D

“…Growth hormone (GH) is critical for achieving normal structural growth. In addition, GH plays an important role in regulating metabolic function. GH acts…”
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Molecular evidence and clinical importance of β‐arrestins expression in patients with acromegaly by Coelho, Maria Caroline Alves, Vasquez, Marina Lipkin, Wildemberg, Luiz Eduardo, Vázquez‐Borrego, Mari C., Bitana, Luciana, Camacho, Aline Helen da Silva, Silva, Débora, Ogino, Liana Lumi, Ventura, Nina, Chimelli, Leila, Luque, Raul M., Kasuki, Leandro, Gadelha, Mônica R.

“…β‐arrestins seem to have a role in endocytosis and desensitization of somatostatin receptor subtype 2 (sst2) and could be associated with the responsiveness to…”
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Biguanides Exert Antitumoral Actions in Pituitary Tumor Cells Through AMPK-Dependent and -Independent Mechanisms by Vázquez-Borrego, Mari C, Fuentes-Fayos, Antonio C, Herrera-Martínez, Aura D, L-López, Fernando, Ibáñez-Costa, Alejandro, Moreno-Moreno, Paloma, Alhambra-Expósito, María R, Barrera-Martín, Ana, Blanco-Acevedo, Cristóbal, Dios, Elena, Venegas-Moreno, Eva, Solivera, Juan, Gahete, Manuel D, Soto-Moreno, Alfonso, Gálvez-Moreno, María A, Castaño, Justo P, Luque, Raúl M

“…Abstract Context Pituitary neuroendocrine tumors (PitNETs) are a commonly underestimated pathology in terms of incidence and associated morbimortality…”
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Are there any completely sterile organs or tissues in the human body? Is there any sacred place? by Michán‐Doña, Alfredo, Vázquez‐Borrego, Mari C., Michán, Carmen

“…The human microbiome comprises an ample set of organisms that inhabit and interact within the human body, contributing both positively and negatively to our…”
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Epigenetic and post‐transcriptional regulation of somatostatin receptor subtype 5 (SST5) in pituitary and pancreatic neuroendocrine tumors by Pedraza‐Arevalo, Sergio, Ibáñez‐Costa, Alejandro, Blázquez‐Encinas, Ricardo, Branco, Miguel R., Vázquez‐Borrego, Mari C., Herrera‐Martínez, Aura D., Venegas‐Moreno, Eva, Serrano‐Blanch, Raquel, Arjona‐Sánchez, Álvaro, Gálvez‐Moreno, María A., Korbonits, Marta, Soto‐Moreno, Alfonso, Gahete, Manuel D., Charalambous, Marika, Luque, Raúl M., Castaño, Justo P.

“…Somatostatin receptor subtype 5 (SST5) is an emerging biomarker and actionable target in pituitary (PitNETs) and pancreatic (PanNETs) neuroendocrine tumors…”
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A New Generation Somatostatin-Dopamine Analogue Exerts Potent Antitumoral Actions on Pituitary Neuroendocrine Tumor Cells by Vázquez-Borrego, Mari C, L-López, Fernando, Gálvez-Moreno, María A, Fuentes-Fayos, Antonio C, Venegas-Moreno, Eva, Herrera-Martínez, Aura D, Blanco-Acevedo, Cristóbal, Solivera, Juan, Landsman, Tanya, Gahete, Manuel D, Soto-Moreno, Alfonso, Culler, Michael D, Castaño, Justo P, Luque, Raúl M

“…Pituitary neuroendocrine tumors (PitNETs) represent approximately 15% of all intracranial tumors and usually are associated with severe comorbidities…”
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The Pituitary Gland is a Novel Major Site of Action of Metformin in Non-Human Primates: a Potential Path to Expand and Integrate Its Metabolic Actions by Vázquez-Borrego, Mari C., Fuentes-Fayos, Antonio C., Gahete, Manuel D., Castaño, Justo P., Kineman, Rhonda D., Luque, Raúl M.

“…Background/Aims: Biguanides are anti-hyperglycaemic agents used to treat diabetes by acting primarily on the liver, inhibiting hepatic gluconeogenesis…”
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Breaking the Mucin Barrier: A New Affinity Chromatography-Mass Spectrometry Approach to Unveil Potential Cell Markers and Pathways Altered in Pseudomyxoma Peritonei by Romero-Ruiz, Antonio, Granados-Rodríguez, Melissa, Bura, Florina I, Valenzuela-Molina, Francisca, Rufián-Andújar, Blanca, Martínez-López, Ana, Rodríguez-Ortiz, Lidia, Ortega-Salas, Rosa, Torres-Martínez, María, Moreno-Serrano, Ana, Castaño, Justo, Michán, Carmen, Alhama, José, Vázquez-Borrego, Mari C, Arjona-Sánchez, Álvaro

“…Pseudomyxoma peritonei (PMP) is a rare peritoneal mucinous carcinomatosis with largely unknown underlying molecular mechanisms. Cytoreductive surgery combined…”
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Intraoperative oxygen tension and redox homeostasis in Pseudomyxoma peritonei: A short case series by Valenzuela-Molina, Francisca, Bura, Florina I, Vázquez-Borrego, Mari C, Granados-Rodríguez, Melissa, Rufián-Andujar, Blanca, Rufián-Peña, Sebastián, Casado-Adam, Ángela, Sánchez-Hidalgo, Juan Manuel, Rodríguez-Ortiz, Lidia, Ortega-Salas, Rosa, Martínez-López, Ana, Michán, Carmen, Alhama, José, Arjona-Sánchez, Álvaro, Romero-Ruiz, Antonio

“…Pseudomyxoma peritonei (PMP) is a rare malignant disease characterized by a massive multifocal accumulation of mucin within the peritoneal cavity. The current…”
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Antitumor effect of a small-molecule inhibitor of KRASG12D in xenograft models of mucinous appendicular neoplasms by Vázquez-Borrego, Mari C., Granados-Rodríguez, Melissa, Bura, Florina I., Martínez-López, Ana, Rufián-Andújar, Blanca, Valenzuela-Molina, Francisca, Rodríguez-Ortiz, Lidia, Haro-Yuste, Sergio, Moreno-Serrano, Ana, Ortega-Salas, Rosa, Pineda-Reyes, Rafael, Michán, Carmen, Alhama, José, Romero-Ruiz, Antonio, Arjona-Sánchez, Álvaro

“…Pseudomyxoma peritonei (PMP) is a rare disease characterized by a massive accumulation of mucus in the peritoneal cavity. The only effective treatment is…”
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Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF3 by Fuentes-Fayos, Antonio C, Vázquez-Borrego, Mari C, Jiménez-Vacas, Juan M, Bejarano, Leire, Pedraza-Arévalo, Sergio, L-López, Fernando, Blanco-Acevedo, Cristóbal, Sánchez-Sánchez, Rafael, Reyes, Oscar, Ventura, Sebastián, Solivera, Juan, Breunig, Joshua J, Blasco, María A, Gahete, Manuel D, Castaño, Justo P, Luque, Raúl M

“…Glioblastomas remain the deadliest brain tumour, with a dismal ∼12-16-month survival from diagnosis. Therefore, identification of new diagnostic, prognostic…”
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A Somatostatin Receptor Subtype-3 (SST 3 ) Peptide Agonist Shows Antitumor Effects in Experimental Models of Nonfunctioning Pituitary Tumors by Vázquez-Borrego, Mari C, Gupta, Vandana, Ibáñez-Costa, Alejandro, Gahete, Manuel D, Venegas-Moreno, Eva, Toledano-Delgado, Álvaro, Cano, David A, Blanco-Acevedo, Cristóbal, Ortega-Salas, Rosa, Japón, Miguel A, Barrera-Martín, Ana, Vasiljevic, Alexandre, Hill, Jason, Zhang, Shengwen, Halem, Heather, Solivera, Juan, Raverot, Gérald, Gálvez, María A, Soto-Moreno, Alfonso, Paez-Pereda, Marcelo, Culler, Michael D, Castaño, Justo P, Luque, Raúl M

“…Somatostatin analogues (SSA) are efficacious and safe treatments for a variety of neuroendocrine tumors, especially pituitary neuroendocrine tumors (PitNET)…”
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Octreotide and pasireotide (dis)similarly inhibit pituitary tumor cells in vitro by Ibáñez-Costa, Alejandro, Rivero-Cortés, Esther, Vázquez-Borrego, Mari C, Gahete, Manuel D, Jiménez-Reina, Luis, Venegas-Moreno, Eva, de la Riva, Andrés, Arráez, Miguel Ángel, González-Molero, Inmaculada, Schmid, Herbert A, Maraver-Selfa, Silvia, Gavilán-Villarejo, Inmaculada, García-Arnés, Juan Antonio, Japón, Miguel A, Soto-Moreno, Alfonso, Gálvez, María A, Luque, Raúl M, Castaño, Justo P

“…Somatostatin analogs (SSA) are the mainstay of pharmacological treatment for pituitary adenomas. However, some patients escape from therapy with octreotide, a…”
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Integrative Clinical, Radiological, and Molecular Analysis for Predicting Remission and Recurrence of Cushing Disease by Moreno-Moreno, Paloma, Ibáñez-Costa, Alejandro, Venegas-Moreno, Eva, Fuentes-Fayos, Antonio C, Alhambra-Expósito, María R, Fajardo-Montañana, Carmen, García-Martínez, Araceli, Dios, Elena, Vázquez-Borrego, Mari C, Remón-Ruiz, Pablo, Cámara, Rosa, Lamas, Cristina, Carlos Padillo-Cuenca, José, Solivera, Juan, Cano, David A, Gahete, Manuel D, Herrera-Martínez, Aura D, Picó, Antonio, Soto-Moreno, Alfonso, Gálvez-Moreno, María Ángeles, Castaño, Justo P, Luque, Raúl M

“…Adrenocorticotropin (ACTH)-secreting pituitary tumors (ACTHomas) are associated with severe comorbidities and increased mortality. Current treatments mainly…”
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Clinical significance of filamin A in patients with acromegaly and its association with somatostatin and dopamine receptor profiles by Coelho, Maria Caroline Alves, Vasquez, Marina Lipkin, Wildemberg, Luiz Eduardo, Vázquez-Borrego, Mari C., Bitana, Luciana, Camacho, Aline Helen da Silva, Silva, Débora, Ogino, Liana Lumi, Ventura, Nina, Sánchez-Sánchez, Rafael, Chimelli, Leila, Kasuki, Leandro, Luque, Raul M., Gadelha, Mônica R.

“…Filamin-A (FLNA) plays a crucial role in somatostatin receptor (sst) subtype-2 signaling in somatotropinomas. Our objective was to investigate the in vivo…”
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Splicing Machinery is Dysregulated in Pituitary Neuroendocrine Tumors and is Associated with Aggressiveness Features by Vázquez-Borrego, Mari C., Fuentes-Fayos, Antonio C., Venegas-Moreno, Eva, Rivero-Cortés, Esther, Dios, Elena, Moreno-Moreno, Paloma, Madrazo-Atutxa, Ainara, Remón, Pablo, Solivera, Juan, Wildemberg, Luiz E., Kasuki, Leandro, López-Fernández, Judith M., Gadelha, Mônica R., Gálvez-Moreno, María A., Soto-Moreno, Alfonso, Gahete, Manuel D., Castaño, Justo P., Luque, and Raúl M.

“…Pituitary neuroendocrine tumors (PitNETs) constitute approximately 15% of all brain tumors, and most have a sporadic origin. Recent studies suggest that…”
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Association between radiological parameters and clinical and molecular characteristics in human somatotropinomas by Alhambra-Expósito, María R., Ibáñez-Costa, Alejandro, Moreno-Moreno, Paloma, Rivero-Cortés, Esther, Vázquez-Borrego, Mari C., Blanco-Acevedo, Cristóbal, Toledano-Delgado, Álvaro, Lombardo-Galera, María S., Vallejo-Casas, Juan A., Gahete, Manuel D., Castaño, Justo P., Gálvez, María A., Luque, Raúl M.

“…Acromegaly is a rare but severe disease, originated in 95% of cases by a growth hormone-secreting adenoma (somatotropinoma) in the pituitary. Magnetic…”
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BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas by Ibáñez-Costa, Alejandro, López-Sánchez, Laura M., Gahete, Manuel D., Rivero-Cortés, Esther, Vázquez-Borrego, Mari C., Gálvez, María A., de la Riva, Andrés, Venegas-Moreno, Eva, Jiménez-Reina, Luis, Moreno-Carazo, Alberto, Tinahones, Francisco J., Maraver-Selfa, Silvia, Japón, Miguel A., García-Arnés, Juan A., Soto-Moreno, Alfonso, Webb, Susan M., Kineman, Rhonda D., Culler, Michael D., Castaño, Justo P., Luque, Raúl M.

“…Chimeric somatostatin/dopamine compounds such as BIM-23A760, an sst2/sst5/D 2 receptors-agonist, have emerged as promising new approaches to treat pituitary…”
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E‐cadherin expression is associated with somatostatin analogue response in acromegaly by Venegas‐Moreno, Eva, Flores‐Martinez, Alvaro, Dios, Elena, Vazquez‐Borrego, Mari C., Ibañez‐Costa, Alejandro, Madrazo‐Atutxa, Ainara, Japón, Miguel A., Castaño, Justo P., Luque, Raúl M., Cano, David A., Soto‐Moreno, Alfonso

“…Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary…”
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Association between dopamine and somatostatin receptor expression and pharmacological response to somatostatin analogues in acromegaly by Venegas‐Moreno, Eva, Vazquez‐Borrego, Mari C., Dios, Elena, Gros‐Herguido, Noelia, Flores‐Martinez, Alvaro, Rivero‐Cortés, Esther, Madrazo‐Atutxa, Ainara, Japón, Miguel A., Luque, Raúl M., Castaño, Justo P., Cano, David A., Soto‐Moreno, Alfonso

“…Acromegaly is a hormonal disorder resulting from excessive growth hormone (GH) secretion frequently produced by pituitary adenomas and consequent increase in…”
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