Search Results - "Vásquez‐Trincado, César"

Mitochondrial dynamics, mitophagy and cardiovascular disease by Vásquez‐Trincado, César, García‐Carvajal, Ivonne, Pennanen, Christian, Parra, Valentina, Hill, Joseph A., Rothermel, Beverly A., Lavandero, Sergio

“…Cardiac hypertrophy is often initiated as an adaptive response to haemodynamic stress or myocardial injury, and allows the heart to meet an increased demand…”
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Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway by Sotomayor-Flores, Cristian, Rivera-Mejías, Pablo, Vásquez-Trincado, César, López-Crisosto, Camila, Morales, Pablo E., Pennanen, Christian, Polakovicova, Iva, Aliaga-Tobar, Víctor, García, Lorena, Roa, Juan Carlos, Rothermel, Beverly A., Maracaja-Coutinho, Vinicius, Ho-Xuan, Hung, Meister, Gunter, Chiong, Mario, Ocaranza, María Paz, Corvalán, Alejandro H., Parra, Valentina, Lavandero, Sergio

“…Angiotensin-(1–9) is a peptide from the noncanonical renin-angiotensin system with anti-hypertrophic effects in cardiomyocytes via an unknown mechanism. In the…”
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Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance by Troncoso, Rodrigo, Paredes, Felipe, Parra, Valentina, Gatica, Damián, Vásquez-Trincado, César, Quiroga, Clara, Bravo-Sagua, Roberto, López-Crisosto, Camila, Rodriguez, Andrea E, Oyarzún, Alejandra P, Kroemer, Guido, Lavandero, Sergio

“…Glucocorticoids, such as dexamethasone, enhance protein breakdown via ubiquitin-proteasome system. However, the role of autophagy in organelle and protein…”
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Polycystin-1 is required for insulin-like growth factor 1-induced cardiomyocyte hypertrophy by Fernández, Carolina, Torrealba, Natalia, Altamirano, Francisco, Garrido-Moreno, Valeria, Vásquez-Trincado, César, Flores-Vergara, Raúl, López-Crisosto, Camila, Ocaranza, María Paz, Chiong, Mario, Pedrozo, Zully, Lavandero, Sergio

“…Cardiac hypertrophy is the result of responses to various physiological or pathological stimuli. Recently, we showed that polycystin-1 participates in…”
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Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake by del Campo, Andrea, Parra, Valentina, Vásquez-Trincado, César, Gutiérrez, Tomás, Morales, Pablo E, López-Crisosto, Camila, Bravo-Sagua, Roberto, Navarro-Marquez, Mario F, Verdejo, Hugo E, Contreras-Ferrat, Ariel, Troncoso, Rodrigo, Chiong, Mario, Lavandero, Sergio

“…Insulin is a major regulator of glucose metabolism, stimulating its mitochondrial oxidation in skeletal muscle cells. Mitochondria are dynamic organelles that…”
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Effects of Metformin on Ischemia/Reperfusion Injury: New Evidence and Mechanisms by Osorio-Llanes, Estefanie, Villamizar-Villamizar, Wendy, Ospino Guerra, María Clara, Díaz-Ariza, Luis Antonio, Castiblanco-Arroyave, Sara Camila, Medrano, Luz, Mengual, Daniela, Belón, Ricardo, Castellar-López, Jairo, Sepúlveda, Yanireth, Vásquez-Trincado, César, Chang, Aileen Y, Bolívar, Samir, Mendoza-Torres, Evelyn

“…The search for new drugs with the potential to ensure therapeutic success in the treatment of cardiovascular diseases has become an essential pathway to follow…”
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Myristate induces mitochondrial fragmentation and cardiomyocyte hypertrophy through mitochondrial E3 ubiquitin ligase MUL1 by Vásquez-Trincado, César, Navarro-Márquez, Mario, Morales, Pablo E, Westermeier, Francisco, Chiong, Mario, Parra, Valentina, Espinosa, Alejandra, Lavandero, Sergio

“…Cardiovascular diseases, especially metabolic-related disorders, are progressively growing worldwide due to high-fat-containing foods, which promote a…”
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Frataxin deficiency lowers lean mass and triggers the integrated stress response in skeletal muscle by Vásquez-Trincado, César, Dunn, Julia, Han, Ji In, Hymms, Briyanna, Tamaroff, Jaclyn, Patel, Monika, Nguyen, Sara, Dedio, Anna, Wade, Kristin, Enigwe, Chinazo, Nichtova, Zuzana, Lynch, David R, Csordas, Gyorgy, McCormack, Shana E, Seifert, Erin L

“…Friedreich's ataxia (FRDA) is an inherited disorder caused by reduced levels of frataxin (FXN), which is required for iron-sulfur cluster biogenesis…”
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Alteration in mitochondrial Ca2+ uptake disrupts insulin signaling in hypertrophic cardiomyocytes by Gutiñrrez, Tomás, Parra, Valentina, Troncoso, Rodrigo, Pennanen, Christian, Contreras-Ferrat, Ariel, Vasquez-Trincado, Cñsar, Morales, Pablo E, Lopez-Crisosto, Camila, Sotomayor-Flores, Cristian, Chiong, Mario, Rothermel, Beverly A, Lavandero, Sergio

“…Cardiac hypertrophy is characterized by alterations in both cardiac bioenergetics and insulin sensitivity. Insulin promotes glucose uptake by cardiomyocytes…”
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Sarcoplasmic reticulum–mitochondria communication in cardiovascular pathophysiology by Lopez-Crisosto, Camila, Pennanen, Christian, Vasquez-Trincado, Cesar, Morales, Pablo E., Bravo-Sagua, Roberto, Quest, Andrew F. G., Chiong, Mario, Lavandero, Sergio

“…Key Points Sarco/endoplasmic reticulum–mitochondria communication and mitochondrial dynamics are essential regulators of mitochondrial function, cellular…”
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Adaptation of the heart to frataxin depletion: evidence that integrated stress response can predominate over mTORC1 activation by Vásquez-Trincado, César, Patel, Monika, Sivaramakrishnan, Aishwarya, Bekeová, Carmen, Anderson-Pullinger, Lauren, Wang, Nadan, Tang, Hsin-Yao, Seifert, Erin L

“…Abstract Friedreich’s ataxia is an inherited disorder caused by depletion of frataxin (FXN), a mitochondrial protein required for iron–sulfur cluster (ISC)…”
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Alteration in mitochondrial Ca(2+) uptake disrupts insulin signaling in hypertrophic cardiomyocytes by Gutiérrez, Tomás, Parra, Valentina, Troncoso, Rodrigo, Pennanen, Christian, Contreras-Ferrat, Ariel, Vasquez-Trincado, César, Morales, Pablo E, Lopez-Crisosto, Camila, Sotomayor-Flores, Cristian, Chiong, Mario, Rothermel, Beverly A, Lavandero, Sergio

“…Cardiac hypertrophy is characterized by alterations in both cardiac bioenergetics and insulin sensitivity. Insulin promotes glucose uptake by cardiomyocytes…”
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Herpud1 impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca 2+ -calcineurin-Akt axis by Navarro-Marquez, Mario, Torrealba, Natalia, Troncoso, Rodrigo, Vásquez-Trincado, Cesar, Rodriguez, Marcelo, Morales, Pablo E, Villalobos, Elisa, Eura, Yuka, Garcia, Lorena, Chiong, Mario, Klip, Amira, Jaimovich, Enrique, Kokame, Koichi, Lavandero, Sergio

“…Skeletal muscle plays a central role in insulin-controlled glucose homeostasis. The molecular mechanisms related to insulin resistance in this tissue are…”
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Herpud1 impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca2+-calcineurin-Akt axis by Navarro-Marquez, Mario, Torrealba, Natalia, Troncoso, Rodrigo, Vásquez-Trincado, Cesar, Rodriguez, Marcelo, Morales, Pablo E., Villalobos, Elisa, Eura, Yuka, Garcia, Lorena, Chiong, Mario, Klip, Amira, Jaimovich, Enrique, Kokame, Koichi, Lavandero, Sergio

“…Skeletal muscle plays a central role in insulin-controlled glucose homeostasis. The molecular mechanisms related to insulin resistance in this tissue are…”
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Mitochondrial phosphate carrier depletion in skeletal muscle and Ca2+ homeostasis by Seifert, Erin, Hajnoczky, Gyorgy, Vasquez-Trincado, Cesar, Debattisti, Valentina, Ghosh, Arijita, In Han, Ji, Bekeova, Carmen

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Alteration in mitochondrial Ca 2+ uptake disrupts insulin signaling in hypertrophic cardiomyocytes by Gutiérrez, Tomás, Parra, Valentina, Troncoso, Rodrigo, Pennanen, Christian, Contreras-Ferrat, Ariel, Vasquez-Trincado, César, Morales, Pablo E, Lopez-Crisosto, Camila, Sotomayor-Flores, Cristian, Chiong, Mario, Rothermel, Beverly A, Lavandero, Sergio

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