Search Results - "Uzonyi, Anna"

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  1. 1

    Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution by Dierks, David, Garcia-Campos, Miguel Angel, Uzonyi, Anna, Safra, Modi, Edelheit, Sarit, Rossi, Alice, Sideri, Theodora, Varier, Radhika A., Brandis, Alexander, Stelzer, Yonatan, van Werven, Folkert, Scherz-Shouval, Ruth, Schwartz, Schraga

    Published in Nature methods (01-09-2021)
    “…N 6 -methyladenosine (m6A) is the most prevalent modification of messenger RNA in mammals. To interrogate its functions and dynamics, there is a critical need…”
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  2. 2

    Dissecting the sequence and structural determinants guiding m6A deposition and evolution via inter- and intra-species hybrids by Shachar, Ran, Dierks, David, Garcia-Campos, Miguel Angel, Uzonyi, Anna, Toth, Ursula, Rossmanith, Walter, Schwartz, Schraga

    Published in Genome Biology (15-02-2024)
    “…N6-methyladenosine (m6A) is the most abundant mRNA modification, and controls mRNA stability. m6A distribution varies considerably between and within species…”
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  3. 3

    Dissecting the basis for differential substrate specificity of ADAR1 and ADAR2 by Zambrano-Mila, Marlon S., Witzenberger, Monika, Rosenwasser, Zohar, Uzonyi, Anna, Nir, Ronit, Ben-Aroya, Shay, Levanon, Erez Y., Schwartz, Schraga

    Published in Nature communications (11-12-2023)
    “…Millions of adenosines are deaminated throughout the transcriptome by ADAR1 and/or ADAR2 at varying levels, raising the question of what are the determinants…”
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  4. 4

    Cloning of DNA oligo pools for in vitro expression by Uzonyi, Anna, Nir, Ronit, Schwartz, Schraga

    Published in STAR protocols (18-03-2022)
    “…Oligo library pools are powerful tools for systematic investigation of genetic and transcriptomic machinery such as promoter function and gene regulation,…”
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  5. 5

    A single-embryo, single-cell time-resolved model for mouse gastrulation by Mittnenzweig, Markus, Mayshar, Yoav, Cheng, Saifeng, Ben-Yair, Raz, Hadas, Ron, Rais, Yoach, Chomsky, Elad, Reines, Netta, Uzonyi, Anna, Lumerman, Lior, Lifshitz, Aviezer, Mukamel, Zohar, Orenbuch, Ayelet-Hashahar, Tanay, Amos, Stelzer, Yonatan

    Published in Cell (27-05-2021)
    “…Mouse embryonic development is a canonical model system for studying mammalian cell fate acquisition. Recently, single-cell atlases comprehensively charted…”
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  6. 6

    Exclusion of m6A from splice-site proximal regions by the exon junction complex dictates m6A topologies and mRNA stability by Uzonyi, Anna, Dierks, David, Nir, Ronit, Kwon, Oh Sung, Toth, Ursula, Barbosa, Isabelle, Burel, Cindy, Brandis, Alexander, Rossmanith, Walter, Le Hir, Hervé, Slobodin, Boris, Schwartz, Schraga

    Published in Molecular cell (19-01-2023)
    “…N6-methyladenosine (m6A), a widespread destabilizing mark on mRNA, is non-uniformly distributed across the transcriptome, yet the basis for its selective…”
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  7. 7

    Deciphering the principles of the RNA editing code via large-scale systematic probing by Uzonyi, Anna, Nir, Ronit, Shliefer, Ofir, Stern-Ginossar, Noam, Antebi, Yaron, Stelzer, Yonatan, Levanon, Erez Y., Schwartz, Schraga

    Published in Molecular cell (03-06-2021)
    “…Adenosine-to-inosine editing is catalyzed by ADAR1 at thousands of sites transcriptome-wide. Despite intense interest in ADAR1 from physiological,…”
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  8. 8

    Dynamic Interaction of Eukaryotic Initiation Factor 4G1 (eIF4G1) with eIF4E and eIF1 Underlies Scanning-Dependent and -Independent Translation by Haimov, Ora, Sehrawat, Urmila, Tamarkin-Ben Harush, Ana, Bahat, Anat, Uzonyi, Anna, Will, Alexander, Hiraishi, Hiroyuki, Asano, Katsura, Dikstein, Rivka

    Published in Molecular and cellular biology (01-09-2018)
    “…Translation initiation of most mRNAs involves m7G-cap binding, ribosomal scanning, and AUG selection. Initiation from an m7G-cap-proximal AUG can be bypassed…”
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