Search Results - "Uzieliene, Ilona"
-
1
The chondrocyte channelome: A narrative review
Published in Joint, bone, spine : revue du rhumatisme (01-01-2019)“…[Display omitted] •The chondrocyte channelome is a sub-compartment of the membranome and includes a complete set of ion channels and porins expressed in these…”
Get full text
Journal Article -
2
Mechanotransducive Biomimetic Systems for Chondrogenic Differentiation In Vitro
Published in International journal of molecular sciences (07-09-2021)“…Osteoarthritis (OA) is a long-term chronic joint disease characterized by the deterioration of bones and cartilage, which results in rubbing of bones which…”
Get full text
Journal Article -
3
The Role of Physical Stimuli on Calcium Channels in Chondrogenic Differentiation of Mesenchymal Stem Cells
Published in International journal of molecular sciences (01-10-2018)“…Human mesenchymal stem cells (hMSC) are becoming increasingly popular in tissue engineering. They are the most frequently used stem cell source for clinical…”
Get full text
Journal Article -
4
Non-viral Gene Therapy for Osteoarthritis
Published in Frontiers in bioengineering and biotechnology (13-01-2021)“…Strategies for delivering nucleic acids into damaged and diseased tissues have been divided into two major areas: viral and non-viral gene therapy. In this…”
Get full text
Journal Article -
5
Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair
Published in International journal of molecular sciences (01-02-2023)“…The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of…”
Get full text
Journal Article -
6
The Effect of CaV1.2 Inhibitor Nifedipine on Chondrogenic Differentiation of Human Bone Marrow or Menstrual Blood-Derived Mesenchymal Stem Cells and Chondrocytes
Published in International journal of molecular sciences (01-04-2023)“…Cartilage is an avascular tissue and sensitive to mechanical trauma and/or age-related degenerative processes leading to the development of osteoarthritis…”
Get full text
Journal Article -
7
The Effects of Mechanical Load on Chondrogenic Responses of Bone Marrow Mesenchymal Stem Cells and Chondrocytes Encapsulated in Chondroitin Sulfate-Based Hydrogel
Published in International journal of molecular sciences (02-02-2023)“…Articular cartilage is vulnerable to mechanical overload and has limited ability to restore lesions, which leads to the development of chronic diseases such as…”
Get full text
Journal Article -
8
Nanotechnological Strategies for Osteoarthritis Diagnosis, Monitoring, Clinical Management, and Regenerative Medicine: Recent Advances and Future Opportunities
Published in Current rheumatology reports (04-04-2020)“…Purpose of Review In this review article, we discuss the potential for employing nanotechnological strategies for the diagnosis, monitoring, and clinical…”
Get full text
Journal Article -
9
Cardiovascular Drugs and Osteoarthritis: Effects of Targeting Ion Channels
Published in Cells (Basel, Switzerland) (28-09-2021)“…Osteoarthritis (OA) and cardiovascular diseases (CVD) share many similar features, including similar risk factors and molecular mechanisms. A great number of…”
Get full text
Journal Article -
10
Different phenotypes and chondrogenic responses of human menstrual blood and bone marrow mesenchymal stem cells to activin A and TGF-β3
Published in Stem cell research & therapy (29-04-2021)“…Due to its low capacity for self-repair, articular cartilage is highly susceptible to damage and deterioration, which leads to the development of degenerative…”
Get full text
Journal Article -
11
Stimulation of Chondrocyte and Bone Marrow Mesenchymal Stem Cell Chondrogenic Response by Polypyrrole and Polypyrrole/Gold Nanoparticles
Published in Polymers (03-06-2023)“…Bone marrow mesenchymal stem cells (BMMSCs) possess a strong ability to differentiate into the chondrogenic lineage, which is important for cartilage…”
Get full text
Journal Article -
12
Electrical Stimulation in Cartilage Tissue Engineering
Published in Bioengineering (Basel) (01-04-2023)“…Electrical stimulation (ES) has been frequently used in different biomedical applications both in vitro and in vivo. Numerous studies have demonstrated…”
Get full text
Journal Article -
13
The Antihypertensive Drug Nifedipine Modulates the Metabolism of Chondrocytes and Human Bone Marrow-Derived Mesenchymal Stem Cells
Published in Frontiers in endocrinology (Lausanne) (08-11-2019)“…Aging is associated with the development of various chronic diseases, in which both cardiovascular disorders and osteoarthritis are dominant. Currently, there…”
Get full text
Journal Article -
14
Modeling the Effect of Annulus Fibrosus Stiffness on the Stressed State of a Vertebral L1 Body and Nucleus Pulposus
Published in Bioengineering (Basel) (01-04-2024)“…The investigation examines the transference of stiffness from intervertebral discs (IVDs) to the lumbar body of the L1 vertebra and the interactions among…”
Get full text
Journal Article -
15
Emerging Technologies and Platforms for the Immunodetection of Multiple Biochemical Markers in Osteoarthritis Research and Therapy
Published in Frontiers in medicine (21-10-2020)“…Biomarkers, especially biochemical markers, are important in osteoarthritis (OA) research, clinical trials, and drug development and have potential for more…”
Get full text
Journal Article -
16
Evaluation of Cartilage Integrity following Administration of Oral and Intraarticular Nifedipine in a Murine Model of Osteoarthritis
Published in Biomedicines (01-09-2023)“…Osteoarthritis (OA) ranks as the prevailing type of arthritis on a global scale, for which no effective treatments are currently available. Arterial…”
Get full text
Journal Article -
17
Menstrual Blood-Derived Stem Cell Paracrine Factors Possess Stimulatory Effects on Chondrogenesis In Vitro and Diminish the Degradation of Articular Cartilage during Osteoarthritis
Published in Bioengineering (Basel) (24-08-2023)“…Articular cartilage is an avascular tissue with a limited capacity for self-regeneration, leading the tissue to osteoarthritis (OA). Mesenchymal stem cells…”
Get full text
Journal Article -
18
Modeling the Impact of Meniscal Tears on von Mises Stress of Knee Cartilage Tissue
Published in Bioengineering (Basel) (01-03-2023)“…The present study aims to explore the stressed state of cartilage using various meniscal tear models. To perform this research, the anatomical model of the…”
Get full text
Journal Article -
19
New Horizons in Hydrogels for Methotrexate Delivery
Published in Gels (30-12-2020)“…Since its first clinical application, methotrexate (MTX) has been widely used for the treatment of human diseases. Despite great advantages, some properties…”
Get full text
Journal Article -
20
Modulation of Chondrogenesis and Senescence in Nucleus Pulposus Cells from Intervertebral Disc
Published in Osteoarthritis and cartilage (01-06-2024)Get full text
Journal Article