Search Results - "Uyar, Ruhi"

Identification of miRNA signatures and their therapeutic potentials in prostate cancer by Karadag, Abdullah, Ozen, Ata, Ozkurt, Mete, Can, Cavit, Bozgeyik, Ibrahim, Kabadere, Selda, Uyar, Ruhi

“…Background Herein, we identified miRNA signatures that were able to differentiate malignant prostate cancer from benign prostate hyperplasia and revealed the…”
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Induction of apoptosis in prostate cancer cells by the novel ceramidase inhibitor ceranib-2 by Kus, Gokhan, Kabadere, Selda, Uyar, Ruhi, Kutlu, Hatice Mehtap

“…Ceramidases are key enzymes that decrease ceramide levels in cells. A reduction in ceramide concentration impairs ceramide signalling, and results in apoptosis…”
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Protective Effect of Seleno-l-Methionine on Cyclophosphamide-Induced Urinary Bladder Toxicity in Rats by Ayhanci, Adnan, Yaman, Suzan, Sahinturk, Varol, Uyar, Ruhi, Bayramoglu, Gokhan, Senturk, Hakan, Altuner, Yilmaz, Appak, Sila, Gunes, Sibel

“…Cyclophosphamide (CP) is a widely used antineoplastic drug, which could cause toxicity of the normal cells due to its toxic metabolites. Its urotoxicity may…”
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Leptin protects the cardiac myocyte cultures from hypoxic damage by Erkasap, Nilufer, Ikizler, Murat, Shneyvays, Vladimir, Zinman, Tova, Mamedova, Liaman K., Uyar, Ruhi, Shainberg, Asher

“…Leptin, a circulating hormone mainly produced by adipose tissue, regulates fatty acid metabolism and causes multiple systemic biological actions even the…”
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Erythropoietin changes contractility, cAMP, and nitrite levels of isolated rat hearts by Kaygisiz, Ziya, Erkasap, Nilufer, Yazihan, Nuray, Sayar, Kemal, Ataoglu, Haluk, Uyar, Ruhi, Ikizler, Murat

“…There is enough evidence that erythropoietin (EPO) may be involved in cardiovascular function. Therefore we have investigated the possible effects of EPO on…”
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Protective Effects of Selenium on Cyclophosphamide-Induced Oxidative Stress and Kidney Injury by Gunes, Sibel, Sahinturk, Varol, Uslu, Sema, Ayhanci, Adnan, Kacar, Sedat, Uyar, Ruhi

“…Cyclophosphamide (CP) is a common anticancer drug, but its use in cancer treatment is limited due to its severe toxicities induced mainly by oxidative stress…”
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actions of leptin on survival and hydrogen peroxide toxicity in primary mixed glial cells of rat by Kabadere, Selda, Gokhan Kus, Ruhi Uyar, Pinar Oztopcu-Vatan, Nilufer Erkasap, Hulyam Kurt, Hasan Gunes

“…Studies indicate that leptin is involved in not only energy expenditure and food intake, but also in protection against apoptosis, in inflammation and in…”
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Carvacrol attenuates cyclophosphamide-induced oxidative stress in rat kidney by Gunes, Sibel, Ayhanci, Adnan, Sahinturk, Varol, Altay, Diler Us, Uyar, Ruhi

“…Cyclophosphamide (CP) is an antineoplastic drug that induces kidney damage via producing oxidative stress. Carvacrol (CAR) has antioxidative effect and we…”
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MgSO4 and lazaroid (U-83836E) partially protects glioma cells against glutamate toxicity in vitro by Kabadere, Selda, Oztopçu, Pinar, Korkmaz, Seval, Erol, Kevser, Uyar, Ruhi

“…In this study, the possible effects of MgSO4 and lazaroid (U-83836E) on glutamate toxicity on glial cells were investigated. C6 and human glioblastoma…”
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Determination of Antiproliferative Effects of Exopolysaccharides from Six Mushroom Species on Glioma Cells by CAN CAKA, Serife, ÖZTOPCU VATAN, Pınar, KABADERE, Selda, YAMAÇ, Mustafa, UYAR, Ruhi

“…Glial tumors are the largest and danger group of central nervous system tumors. The use of natural products now has been contemplated of exceptional value in…”
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Acute Erythropoietin Infusion Increases Rat Glomerular Filtration Rate by Partly Stimulating Intrarenal Nitric Oxide Production by Uzuner, Kubilay, Yazihan, Nuray, Aydin, Yasemin, Uyar, Ruhi, Bagla, Suat

“…Currently, erythropoietin (EPO) treatment in anemic patients is getting more interest, but in long term, development of hypertension is common problem in EPO…”
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Seleno l-Methionine Acts on Cyclophosphamide-Induced Kidney Toxicity by Ayhanci, Adnan, Günes, Sibel, Sahinturk, Varol, Appak, Sila, Uyar, Ruhi, Cengiz, Mustafa, Altuner, Yilmaz, Yaman, Suzan

“…The anticancer drug cyclophosphamide (CP) has nephrotoxic effects besides its urotoxicity, which both in turn limit its clinical utility. The nephrotoxicity of…”
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Antiproliferative Properties of the Lazaroids U-83836E and U-74389G on Glioma Cells In Vitro by Durmaz, Ramazan, Deliorman, Selda, Isiksoy, Serap, Uyar, Ruhi, Erol, Kevser, Tel, Esref

“…The 21-aminosteroids (lazaroids) are a new family of steroid compounds that inhibit lipid peroxidation reactions. They are novel antioxidant agents, which have…”
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Comparison of a ceramidase inhibitor (ceranib-2) with C2 ceramide and cisplatin on cytotoxicity and apoptosis of glioma cells by Kuş, Gökhan, Özkurt, Mete, Öztopcu Vatan, Pınar, Erkasap, Nilüfer, Uyar, Ruhi, Kabadere, Selda

“…Inhibiting ceramidase activity in cancer cells has been identified as a promising target for cancer therapy in recent studies. uhTs, we examined the possible…”
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Ciprofloxacin and Pefloxacin Suppress the Inflammatory Response in Rats by Kiliç, Fatma Sultan, Batu, Özlem, Yildirim, Engin, Erol, Kevser, Deliorman, Selda, Uyar, Ruhi

“…It has been known that ciprofloxacin augments the humoral and cellular immune systems. The aim of the present study was to determine whether these properties…”
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Licofelone abolishes survival of carcinogenic fibroblasts by inducing apoptosis by Kabadere, Selda, Kus, Gokhan, Uyar, Ruhi, Oztopcu-Vatan, Pinar

“…Abstract Dual inhibitors of cyclooxygenase (COX) and lipoxygenase (LOX) pathways of arachidonic acid metabolism prevent cancer development and induce…”
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Syntheses, characterization, antimicrobial and cytotoxic activities of pyridine-2,5-dicarboxylate complexes with 1,10-phenanthroline by Colak, Alper Tolga, Oztopcu-Vatan, Pinar, Colak, Ferdag, Akduman, Demet, Kabadere, Selda, Uyar, Ruhi

“…In this study, four mononuclear M(II)-pyridine-2,5-dicarboxylate (M=Co(II), Ni(II), Cu(II) and Zn(II) complexes with pyridine-2,5-dicarboxylic acid or…”
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Cytotoxic and apoptotic effects of ceranib-2 offering potential for a new antineoplastic agent in the treatment of cancer cells by VEJSELOVA, Djanan, KUTLU, Hatice Mehtap, KUŞ, Gökhan, KABADERE, Selda, UYAR, Ruhi

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effect of pretreatment or combined treatment of quercetin on menadione toxicity in rat primary mixed glial cells in vitro by Oztopcu-Vatan, Pinar, Kabadere, Selda, Uyar, Ruhi

“…Neurons and glia are highly susceptible to reactive oxygen species that play a key role in various neurodegenerative diseases. Menadione, a synthetic…”
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Pyridine-2,5-dicarboxylate complexes with 2,2′-bipyridine and Co(II), Zn(II), Cu(II): syntheses, characterization, antimicrobial, and cytotoxic effects by Colak, Alper Tolga, Colak, Ferdag, Oztopcu-Vatan, Pinar, Akduman, Demet, Kabadere, Selda, Uyar, Ruhi

“…In this study, three novel mononuclear M(II)-pyridine-2,5-dicarboxylate (M = Co(II), Cu(II), and Zn(II)) complexes with pyridine-2,5-dicarboxylic acid or…”
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