Search Results - "Uwadiae, Faith"
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Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology
Published in PLoS pathogens (01-09-2017)“…Interleukin-6 is a pleiotropic, pro-inflammatory cytokine that can promote both innate and adaptive immune responses. In humans with respiratory virus…”
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2
T Follicular Helper Cells in Asthma Through Murine Models of Allergic Airway Disease
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…The development of allergen-specific IgE is one of the hallmark symptoms of allergic diseases, including asthma. T follicular helper cells (TFH) are a subset…”
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Targeting the ICOS/ICOS‐L pathway in a mouse model of established allergic asthma disrupts T follicular helper cell responses and ameliorates disease
Published in Allergy (Copenhagen) (01-04-2019)“…Background Allergic asthma is characterized by chronic inflammation and remodelling of the airways, associated with dysregulated type 2 immune responses and…”
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Differential Trafficking and Expression of PIR Proteins in Acute and Chronic Plasmodium Infections
Published in Frontiers in cellular and infection microbiology (16-06-2022)“…Plasmodium multigene families are thought to play important roles in the pathogenesis of malaria. Plasmodium interspersed repeat (pir) genes comprise the…”
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Inception of early-life allergen-induced airway hyperresponsiveness is reliant on IL-13 + CD4 + T cells
Published in Science immunology (07-09-2018)“…Airway hyperresponsiveness (AHR) is a critical feature of wheezing and asthma in children, but the initiating immune mechanisms remain unconfirmed. We…”
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