Search Results - "Uvalle, Crystal"

Prostaglandin D2 pathway upregulation: Relation to asthma severity, control, and TH2 inflammation by Fajt, Merritt L., Gelhaus, Stacy L., Freeman, Bruce, Uvalle, Crystal E., Trudeau, John B., Holguin, Fernando, Wenzel, Sally E.

“…Bronchoalveolar lavage (BAL) fluid prostaglandin D2 (PGD2) levels are increased in patients with severe, poorly controlled asthma in association with…”
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Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma by Manni, Michelle L., Heinrich, Victoria A., Buchan, Gregory J., O’Brien, James P., Uvalle, Crystal, Cechova, Veronika, Koudelka, Adolf, Ukani, Dharti, Rawas-Qalaji, Mohamad, Oury, Tim D., Hart, Renee, Ellgass, Madeline, Mullett, Steven J., Fajt, Merritt L., Wenzel, Sally E., Holguin, Fernando, Freeman, Bruce A., Wendell, Stacy G.

“…Bile acid profiles are altered in obese individuals with asthma. Thus, we sought to better understand how obesity-related systemic changes contribute to lung…”
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Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling by Koudelka, Adolf, Buchan, Gregory J., Cechova, Veronika, O’Brien, James P., Stevenson, Emily R., Uvalle, Crystal E., Liu, Heng, Woodcock, Steven R., Mullett, Steven J., Zhang, Cheng, Freeman, Bruce A., Gelhaus, Stacy L.

“…The enzymatic oxidation of arachidonic acid is proposed to yield trihydroxytetraene species (termed lipoxins) that resolve inflammation via ligand activation…”
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Phenotypic and genotypic association of epithelial IL1RL1 to human TH2-like asthma by Traister, Russell S., Uvalle, Crystal E., Hawkins, Gregory A., Meyers, Deborah A., Bleecker, Eugene R., Wenzel, Sally E.

“…Severe asthma remains poorly characterized, although it likely consists of at least 1 phenotype with features of TH2-like inflammation. IL1RL1, encoding both…”
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Meta-omics profiling of the gut-lung axis illuminates metabolic networks and host-microbial interactions associated with elevated lung elastance in a murine model of obese allergic asthma by Heinrich, Victoria A, Uvalle, Crystal, Manni, Michelle L, Li, Kelvin, Mullett, Steven J, Donepudi, Sri Ramya, Clader, Jason, Fitch, Adam, Ellgass, Madeline, Cechova, Veronika, Qin, Shulin, Holguin, Fernando, Freeman, Bruce A, Methé, Barbara A, Morris, Alison, Gelhaus, Stacy L

“…Obesity and associated changes to the gut microbiome worsen airway inflammation and hyperresponsiveness in asthma. Obesogenic host-microbial metabolomes have…”
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High Blood Eosinophils Predict Reductions In Sputum Mast Cells and Lung Function In Response To Triamcinolone In Asthma by Fajt, Merritt L., Dr, Uvalle, Crystal, Ms, Trudeau, John, Mr, Wenzel, Sally E., MD, FAAAAI

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Nitro-oleic acid redirects energy substrate utilization to shift macrophage polarization by Stevenson, Emily, O'Brien, James, Uvalle, Crystal, Mullett, Steve, Fong, Erica, Freeman, Bruce, Gelhaus, Stacy

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Hepatic Cyp3a11 upregulation by Nitro-oleic acid mitigates NAFLD progression in a murine model of allergic asthma by Donepudi, Sri Ramya, Heinrich, Victoria, Stevenson, Emily, Uvalle, Crystal, Mullett, Steve, Gelhaus, Stacy

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Nitro-oleic acid attenuates pro-inflammatory metabolic signaling in LPS activated macrophages by Uvalle, Crystal, Gelhaus, Stacy, Fong, Erica, Mullett, Steve, Lockwood, Karina, Suber, Tomeka

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Nitro-fatty acids: a pleiotropic therapy for asthma by Heinrich, Victoria, Uvalle, Crystal, Manni, Michelle, Donepudi, Sri Ramya, Normann, Marigny, Fong, Erica, Mullett, Steve, Freeman, Bruce, Gelhaus, Stacy

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Abstract P5-16-17: Targeting homologous recombination-proficient triple negative cancer cells with a novel RAD51 inhibitor by Neumann, Carola Anke, Skoko, John J, Freeman, Bruce A, Schopfer, Francisco, Woodcock, Steven Robert, Chang, Fei, Hong, Lisa, Braden, Dennis Carl, Uvalle, Crystal

“…Out of all breast cancers (BC), ~20% are triple negative breast cancers (TNBC) devoid of the three receptors that define breast cancer treatment strategies…”
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Systemic bile acids potentiate airway hyperresponsiveness and modulate Th17 cell function in obesity-associated asthma by Manni, Michelle L, Heinrich, Victoria A, Uvalle, Crystal E, Manuel, Allison, Ellgass, Madeline R, Mullett, Steven J, Normann, Marigny C, Koziel, Corrine, Fajt, Merritt L, Wenzel, Sally E, Holguin, Fernando, Freeman, Bruce A, Wendell, Stacy L

“…Obesity-associated asthma is phenotypically characterized by low grade inflammation and resistance to standard therapies. Like many other asthma endotypes, the…”
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Phenotypic and genotypic association of epithelialIL1RL1 to human TH2-like asthma by Traister, Russell S, Uvalle, Crystal E, Hawkins, Gregory A, Meyers, Deborah A, Bleecker, Eugene R, Wenzel, Sally E

“…Background Severe asthma remains poorly characterized, although it likely consists of at least 1 phenotype with features of TH2-like inflammation.IL1RL1,…”
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Prostaglandin D2pathway upregulation: Relation to asthma severity, control, and TH2 inflammation by Fajt, Merritt L, Gelhaus, Stacy L, Freeman, Bruce, Uvalle, Crystal E, Trudeau, John B, Holguin, Fernando, Wenzel, Sally E

“…Background Bronchoalveolar lavage (BAL) fluid prostaglandin D2(PGD2) levels are increased in patients with severe, poorly controlled asthma in association with…”
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Prostaglandin D sub(2) pathway upregulation: Relation to asthma severity, control, and T sub(H)2 inflammation by Fajt, Merritt L, Gelhaus, Stacy L, Freeman, Bruce, Uvalle, Crystal E, Trudeau, John B, Holguin, Fernando, Wenzel, Sally E

“…Background: Bronchoalveolar lavage (BAL) fluid prostaglandin D sub(2) (PGD sub(2)) levels are increased in patients with severe, poorly controlled asthma in…”
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Phenotypic and genotypic association of epithelial IL1RL1  to human TH 2-like asthma by Traister, Russell S., MD, PhD, Uvalle, Crystal E., BS, Hawkins, Gregory A., PhD, Meyers, Deborah A., PhD, Bleecker, Eugene R., MD, Wenzel, Sally E., MD

“…Background Severe asthma remains poorly characterized, although it likely consists of at least 1 phenotype with features of TH 2-like inflammation. IL1RL1 ,…”
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Prostaglandin D2 pathway upregulation: Relation to asthma severity, control, and TH 2 inflammation by Fajt, Merritt L., MD, Gelhaus, Stacy L., PhD, Freeman, Bruce, PhD, Uvalle, Crystal E., BS, Trudeau, John B., BA, Holguin, Fernando, MD, MPH, Wenzel, Sally E., MD

“…Background Bronchoalveolar lavage (BAL) fluid prostaglandin D2 (PGD2 ) levels are increased in patients with severe, poorly controlled asthma in association…”
Get full text