Search Results - "Uutela, M"

Reduction of BDNF expression in Fmr1 knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits by Uutela, M., Lindholm, J., Louhivuori, V., Wei, H., Louhivuori, L. M., Pertovaara, A., Åkerman, K., Castrén, E., Castrén, M. L.

“…Fragile X syndrome (FXS) is a common cause of inherited intellectual disability and a well‐characterized form of autism spectrum disorder. As brain‐derived…”
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Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice by Ahlqvist, Kati J., Hämäläinen, Riikka H., Yatsuga, Shuichi, Uutela, Marko, Terzioglu, Mügen, Götz, Alexandra, Forsström, Saara, Salven, Petri, Angers-Loustau, Alexandre, Kopra, Outi H., Tyynismaa, Henna, Larsson, Nils-Göran, Wartiovaara, Kirmo, Prolla, Tomas, Trifunovic, Aleksandra, Suomalainen, Anu

“…Somatic stem cell (SSC) dysfunction is typical for different progeroid phenotypes in mice with genomic DNA repair defects. MtDNA mutagenesis in mice with…”
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PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor by Eriksson, Ulf, Bergsten, Erika, Uutela, Marko, Li, Xuri, Pietras, Kristian, Östman, Arne, Heldin, Carl-Henrik, Alitalo, Kari

“…The term 'platelet-derived growth factor' (PDGF) refers to a family of disulphide-bonded dimeric isoforms that are important for growth, survival and function…”
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PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis by Uutela, Marko, Wirzenius, Maria, Paavonen, Karri, Rajantie, Iiro, He, Yulong, Karpanen, Terhi, Lohela, Marja, Wiig, Helge, Salven, Petri, Pajusola, Katri, Eriksson, Ulf, Alitalo, Kari

“…Platelet-derived growth factor-D (PDGF-D) is a recently characterized member of the PDGF family with unknown in vivo functions. We investigated the effects of…”
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PDGF-C is a new protease-activated ligand for the PDGF α-receptor by Eriksson, Ulf, Li, Xuri, Pontén, Annica, Aase, Karin, Karlsson, Linda, Abramsson, Alexandra, Uutela, Marko, Bäckström, Gudrun, Hellström, Mats, Boström, Hans, Li, Hong, Soriano, Philippe, Betsholtz, Christer, Heldin, Carl-Henrik, Alitalo, Kari, Östman, Arne

“…Platelet-derived growth factors (PDGFs) are important in many types of mesenchymal cell. Here we identify a new PDGF, PDGF-C, which binds to and activates the…”
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Chromosomal location, exon structure, and vascular expression patterns of the human PDGFC and PDGFD genes by UUTELA, Marko, LAUREN, Juha, BERGSTEN, Erika, XURI LI, HORELLI-KUITUNEN, Nina, ERIKSSON, Ulf, ALITALO, Kari

“…Platelet-derived growth factor (PDGF), which is a major mitogen for vascular smooth muscle cells and has been implicated in the pathogenesis of…”
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Repeated centralized multidisciplinary team assessment of resectability, clinical behavior, and outcomes in 1086 Finnish metastatic colorectal cancer patients (RAXO): A nationwide prospective intervention study by Osterlund, Pia, Salminen, Tapio, Soveri, Leena-Maija, Kallio, Raija, Kellokumpu, Ilmo, Lamminmäki, Annamarja, Halonen, Päivi, Ristamäki, Raija, Lantto, Eila, Uutela, Aki, Osterlund, Emerik, Ovissi, Ali, Nordin, Arno, Heervä, Eetu, Lehtomäki, Kaisa, Räsänen, Jari, Murashev, Maija, Aroviita, Laura, Jekunen, Antti, Lindvall-Andersson, Reneé, Nyandoto, Paul, Kononen, Juha, Lepistö, Anna, Poussa, Tuija, Muhonen, Timo, Ålgars, Annika, Isoniemi, Helena

“…Resection of colorectal cancer (CRC) metastases provides good survival but is probably underused in real-world practice. A prospective Finnish nationwide study…”
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VEGFR3 gene structure, regulatory region, and sequence polymorphisms by Iljin, K, Karkkainen, M J, Lawrence, E C, Kimak, M A, Uutela, M, Taipale, J, Pajusola, K, Alhonen, L, Halmekytö, M, Finegold, D N, Ferrell, R E, Alitalo, K

“…Vascular endothelial growth factor receptor 3 (VEGFR-3) is required for cardiovascular development during embryogenesis. In adults, this receptor is expressed…”
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Expression and Glycosylation Studies of Human FGF Receptor 4 by Tuominen, Heidi, Heikinheimo, Pirkko, Loo, Britt-Marie, Kataja, Kari, Oker-Blom, Christian, Uutela, Marko, Jalkanen, Markku, Goldman, Adrian

“…Fibroblast growth factor receptor subtype 4 (FGFR4) has been shown to have special activation properties and just one splicing form, unlike the other FGFRs…”
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