Search Results - "Utzat, Christopher D"

Interactions of human replication protein A with single-stranded DNA adducts by Liu, Yiyong, Yang, Zhengguan, Utzat, Christopher D, Liu, Yu, Geacintov, Nicholas E, Basu, Ashis K, Zou, Yue

“…Human RPA (replication protein A), a single-stranded DNA-binding protein, is required for many cellular pathways including DNA repair, recombination and…”
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Mutagenicity of the 1-Nitropyrene-DNA Adduct N-(Deoxyguanosin-8-yl)-1-aminopyrene in Mammalian Cells by Watt, Danielle L, Utzat, Christopher D, Hilario, Pablo, Basu, Ashis K

“…The mutagenesis of the major DNA adduct N-(deoxyguanosin-8-yl)-1-aminopyrene (C8-AP-dG) formed by 1-nitropyrene was compared with the analogous C8-dG adducts…”
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Effects of DNA Adduct Structure and Sequence Context on Strand Opening of Repair Intermediates and Incision by UvrABC Nuclease by Zou, Yue, Shell, Steven M, Utzat, Christopher D, Luo, Charlie, Yang, Zhengguan, Geacintov, Nicholas E, Basu, Ashis K

“…DNA damage recognition of nucleotide excision repair (NER) in Escherichia coli is achieved by at least two steps. In the first step, a helical distortion is…”
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DNA Adduct of the Mitomycin C Metabolite 2,7-Diaminomitosene Is a Nontoxic and Nonmutagenic DNA Lesion in Vitro and in Vivo by Utzat, Christopher D, Clement, Cristina C, Ramos, Leilani A, Das, Arunangshu, Tomasz, Maria, Basu, Ashis K

“…Mitomycin C (MC) is a cytotoxic and mutagenic antitumor agent that alkylates and cross-links DNA. These effects are dependent on reductive bioactivation of MC…”
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Biological effects of bulky N7- and C8-deoxyguanosine adducts by a site-specific approach by Utzat, Christopher D

“…Compounds that have the ability to alkylate DNA, resulting in the covalent modification of DNA, may induce genetic mutations. Prior studies on the…”
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Biological effects of bulky N7- and C8-deoxyguanosine adducts by a site-specific approach by Utzat, Christopher D

“…Compounds that have the ability to alkylate DNA, resulting in the covalent modification of DNA, may induce genetic mutations. Prior studies on the…”
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Isolation and Characterization of Strains Defective in Vacuolar Ornithine Permease inNeurospora crassa by Keenan, Kelly A., Utzat, Christopher D., Zielinski, Thomas K.

“…Vacuolar uptake of ornithine and lysine was characterized inNeurospora crassausing a cupric ion permeabilization system. Michaelis constants were measured as…”
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Isolation and characterization of strains defective in vacuolar ornithine permease in Neurospora crassa by Keenan, K.A, Utzat, C.D, Zielinski, T.K

“…Vacuolar uptake of ornithine and lysine was characterized in Neurospora crassa using a cupric ion permeabilization system. Michaelis constants were measured as…”
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