Search Results - "Utz, U"

Increasing quantity without compromising quality: How managerial framing affects intrapreneurship by Rigtering, J.P.C. (Coen), Weitzel, G.U. (Utz), Muehlfeld, K. (Katrin)

“…Individual-level opportunity recognition processes are vital to corporate entrepreneurship. However, little is known regarding how managerial communication…”
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Molecular tracking of antigen‐specific T cell clones in neurological immune‐mediated disorders by Muraro, Paolo A., Wandinger, Klaus‐Peter, Bielekova, Bibiana, Gran, Bruno, Marques, Adriana, Utz, Ursula, McFarland, Henry F., Jacobson, Steve, Martin, Roland

“…T cells recognizing self or microbial antigens may trigger or reactivate immune‐mediated diseases. Monitoring the frequency of specific T cell clonotypes to…”
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Analysis of the T-cell receptor repertoire of human T-cell leukemia virus type 1 (HTLV-1) Tax-specific CD8+ cytotoxic T lymphocytes from patients with HTLV-1-associated disease: evidence for oligoclonal expansion by Utz, U, Banks, D, Jacobson, S, Biddison, W E

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Sequence motifs important for peptide binding to the human MHC class I molecule, HLA-A2 by Parker, KC, Bednarek, MA, Hull, LK, Utz, U, Cunningham, B, Zweerink, HJ, Biddison, WE, Coligan, JE

“…Previous studies have indicated that most HLA-A2-binding peptides are 9 amino acid (aa) residues long, with a Leu at position 2 (P2), and a Val or Leu at P9…”
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Identification of a neutralizing epitope on glycoprotein gp58 of human cytomegalovirus by UTZ, U, BRITT, W, VUGLER, L, MACH, M

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Presentation of three different viral peptides, HTLV-1 Tax, HCMV gB, and influenza virus M1, is determined by common structural features of the HLA-A2.1 molecule by Utz, U, Koenig, S, Coligan, JE, Biddison, WE

“…To determine whether similar or dissimilar molecular features of class I molecules are involved in the presentation of structurally distinct peptides, we have…”
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Peptide binding to HLA-A2 and HLA-B27 isolated from Escherichia coli. Reconstitution of HLA-A2 and HLA-B27 heavy chain/beta 2-microglobulin complexes requires specific peptides by Parker, K C, Carreno, B M, Sestak, L, Utz, U, Biddison, W E, Coligan, J E

“…The specificity of peptide binding by human leukocyte antigen (HLA) class I molecules was investigated in a cell-free direct-binding assay. Peptides were…”
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Heterogeneity of T-Cell Receptor α-Chain Complementarity-Determining Region 3 in Myelin Basic Protein-Specific T Cells Increases with Severity of Multiple Sclerosis by Utz, Ursula, Brooks, Janet A., McFarland, Henry F., Martin, Roland, Biddison, William E.

“…The pathogenesis of multiple sclerosis (MS) is thought to involve a T-cell-mediated autoimmune process. Experimental allergic encephalomyelitis (EAE), an…”
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Mapping of the Major Glycoprotein Gene of Human Cytomegalovirus by Mach, Michael, Utz, Ursula, Fleckenstein, Bernhard

“…Institut für Klinische Virologie der Universität Erlangen-Nürnberg, Loschgestrasse 7, D-8520 Erlangen, F.R.G. The gene coding for the most abundant…”
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Structure of the complex between human T-cell receptor, viral peptide and HLA-A2 by Garboczi, David N, Ghosh, Partho, Utz, Ursula, Fan, Qing R, Biddison, William E, Wiley, Don C

“…Recognition by a T-cell antigen receptor (TCR) of peptide complexed with a major histocompatibility complex (MHC) molecule occurs through variable loops in the…”
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Two Human T Cell Receptors Bind in a Similar Diagonal Mode to the HLA-A2/Tax Peptide Complex Using Different TCR Amino Acids by Ding, Yuan-Hua, Smith, Kathrine J., Garboczi, David N., Utz, Ursula, Biddison, William E., Wiley, Don C.

“…The three-dimensional structure of a human αβ T cell receptor (TCR), B7, bound to the HLA-A2 molecule/HTLV-1 Tax peptide complex was determined by x-ray…”
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Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein by Brocke, Stefan, Gijbels, Koenraad, Allegretta, Mark, Ferber, Iris, Piercy, Christopher, Blankensteini, Thomas, Martin, Roland, Utz, Ursula, Karin, Nathan, Mitchell, Dennis, Veromaa, Timo, Waisman, Ari, Gaur, Amitabh, Conlon, Paul, Ling, Nicholas, Fairchild, Paul J, Wraith, David C, O'Garra, Anne, Fathman, C. Garrison, Steinman, Lawrence

“…Following induction of experimental encephalomyelitis with a T-cell clone, L10C1, that is specific for the myelin basic protein epitope p87-99, the…”
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Assembly, specific binding, and crystallization of a human TCR- alpha beta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2 by Garboczi, D N, Utz, U, Ghosh, P, Seth, A, Kim, Jongsun, VanTienhoven, EAE, Biddison, W E, Wiley, D C

“…T lymphocytes use TCR- alpha beta to bind and to recognize complexes of antigenic peptides bound to MHC proteins located at the surface of APCs. We have…”
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Human T cell leukemia virus type I (HTLV-I)-specific CD8+ CTL clones from patients with HTLV-I-associated neurologic disease secrete proinflammatory cytokines, chemokines, and matrix metalloproteinase by Biddison, WE, Kubota, R, Kawanishi, T, Taub, DD, Cruikshank, WW, Center, DM, Connor, EW, Utz, U, Jacobson, S

“…Human T cell leukemia virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic, progressive neurologic disease…”
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Peptide Recognition by Two HLA-A2/Tax11-19-Specific T Cell Clones in Relationship to Their MHC/Peptide/TCR Crystal Structures by Hausmann, Stefan, Biddison, William E, Smith, Kathrine J, Ding, Yuan-Hua, Garboczi, David N, Utz, Ursula, Wiley, Don C, Wucherpfennig, Kai W

“…The crystal structures of two human TCRs specific for a HTLV-I Tax peptide bound to HLA-A2 were recently determined, for the first time allowing a functional…”
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Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87-99) by Vergelli, M, Hemmer, B, Utz, U, Vogt, A, Kalbus, M, Tranquill, L, Conlon, P, Ling, N, Steinman, L, McFarland, H F, Martin, R

“…We have examined the functional consequences induced by interaction of DR2a-restricted myelin basic protein (MBP) (87-99)-specific T cell clones (TCC) with…”
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Skewed T-cell receptor repertoire in genetically identical twins correlates with multiple sclerosis by Utz, Ursula, Biddison, William E, McFarland, Henry F, McFarlin, Dale E, Flerlage, Marjorie, Martin, Roland

“…Although the cause of multiple sclerosis (MS) is unknown, it is thought to involve a T cell-mediated autoimmune mechanism. Susceptibility to the disease is…”
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Diversity in fine specificity and T cell receptor usage of the human CD4+ cytotoxic T cell response specific for the immunodominant myelin basic protein peptide 87-106 by Martin, R, Utz, U, Coligan, JE, Richert, JR, Flerlage, M, Robinson, E, Stone, R, Biddison, WE, McFarlin, DE, McFarland, HF

“…Multiple sclerosis (MS), a human demyelinating disease, is thought to be caused by an autoimmunologic process, and myelin basic protein (MBP) is considered a…”
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Analysis of the expression of peptide-major histocompatibility complexes using high affinity soluble divalent T cell receptors by O'Herrin, S M, Lebowitz, M S, Bieler, J G, al-Ramadi, B K, Utz, U, Bothwell, A L, Schneck, J P

“…Understanding the regulation of cell surface expression of specific peptide-major histocompatibility complex (MHC) complexes is hindered by the lack of direct…”
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Presentation of endogenous peptides to MHC class I-restricted cytotoxic T lymphocytes in transport deletion mutant T2 cells by Zweerink, HJ, Gammon, MC, Utz, U, Sauma, SY, Harrer, T, Hawkins, JC, Johnson, RP, Sirotina, A, Hermes, JD, Walker, BD

“…The ability of minigene-encoded viral peptide epitopes to be presented by class I molecules in the absence of MHC-encoded transporters has been evaluated in…”
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