Search Results - "Utton, M."

Pathological inclusion bodies in tauopathies contain distinct complements of tau with three or four microtubule-binding repeat domains as demonstrated by new specific monoclonal antibodies by De Silva, R., Lashley, T., Gibb, G., Hanger, D., Hope, A., Reid, A., Bandopadhyay, R., Utton, M., Strand, C., Jowett, T., Khan, N., Anderton, B., Wood, N., Holton, J., Revesz, T., Lees, A.

“…Pathological inclusions containing fibrillar aggregates of hyperphosphorylated tau protein are a characteristic feature in the tauopathies, which include…”
Get full text

Stress‐Activated Protein Kinase/c‐Jun N‐Terminal Kinase Phosphorylates τ Protein by Reynolds, C. Hugh, Utton, Michelle A., Gibb, Graham M., Yates, Alexandra, Anderton, Brian H.

“…: A proportion of the neuronal microtubule‐associated protein (MAP) τ is highly phosphorylated in foetal and adult brain, whereas the majority of τ in the…”
Get full text

Reactivating Kinase/p38 Phosphorylates τ Protein In Vitro by Reynolds, C. Hugh, Nebreda, Angel R., Gibb, Graham M., Utton, Michelle A., Anderton, Brian H.

“…: Neurofibrillary tangles, one of the major pathological hallmarks of Alzheimer‐diseased brains, consist primarily of aggregated paired helical filaments…”
Get full text

Soluble N‐cadherin stimulates fibroblast growth factor receptor dependent neurite outgrowth and N‐cadherin and the fibroblast growth factor receptor co‐cluster in cells by Utton, Michelle A., Eickholt, Britta, Howell, Fiona V., Wallis, Julie, Doherty, Patrick

“…A chimeric molecule consisting of the extracellular domain of the adhesion molecule, N‐cadherin, fused to the Fc region of human IgG (NCAD‐Fc) supports…”
Get full text

Functional Differences of Tau Isoforms Containing 3 or 4 C-terminal Repeat Regions and the Influence of Oxidative Stress by Utton, Michelle A., Gibb, Graham M., Burdett, Ian D.J., Anderton, Brian H., Vandecandelaere, André

“…We report functional differences between tau isoforms with 3 or 4 C-terminal repeats and a difference in susceptibility to oxidative conditions, with respect…”
Get full text

Large Firm Diversification in British Manufacturing Industry by Utton, M. A.

Get full text

DOMESTIC CONCENTRATION AND INTERNATIONAL TRADE by Utton, M. A.

Get full text

Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation by Wagner, U, Utton, M, Gallo, J M, Miller, C C

“…Tau is a neuronal microtubule-associated protein that appears to function in the formation and maintenance of axons by influencing microtubule organisation…”
Get full text

Aggregate Versus Market Concentration: A Note by Utton, M. A.

Get full text

The Effect of Mergers on Concentration: U.K. Manufacturing Industry, 1954-65 by Utton, M. A.

Get full text

DIVERSIFICATION AND COMPETITION by Utton, M. A.

“…This note summarises the main findings of a forthcoming National Institute Occasional Paper (Number XXXI to be published on 6 September)…”
Get full text

Molecular motors implicated in the axonal transport of tau and alpha-synuclein by Utton, Michelle A, Noble, Wendy J, Hill, Josephine E, Anderton, Brian H, Hanger, Diane P

“…Tau and alpha-synuclein are both proteins implicated in the pathology of neurodegenerative disease. Here we have investigated the mechanisms of axonal…”
Get full text

Fifty Years of U.K. Competition Policy by UTTON, MICHAEL

“…The first statute of modern times in Britain dealing with competition policy was passed 50 years ago. Since then the policy has been extended and changed in a…”
Get full text

Strategic behaviour of incumbent firms in the UK by Singh, Satwinder, Utton, Michael, Waterson, Michael

“…The main purpose of this paper is to examine the incidence of strategic behaviour in the UK by means of a questionnaire study performed across three broad…”
Get full text

Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons by Saha, Anirban R, Hill, Josephine, Utton, Michelle A, Asuni, Ayodeji A, Ackerley, Steven, Grierson, Andrew J, Miller, Christopher C, Davies, Alun M, Buchman, Vladimir L, Anderton, Brian H, Hanger, Diane P

“…Alpha-synuclein is a major protein constituent of Lewy bodies and mutations in alpha-synuclein cause familial autosomal dominant Parkinson's disease. One…”
Get full text

Differences in the regulation of microtubule dynamics by microtubule-associated proteins MAP1B and MAP2 by Vandecandelaere, André, Pedrotti, Barbara, Utton, Michelle A., Calvert, Rosy A., Bayley, Peter M.

“…The regulation of microtubule dynamics in vitro by microtubule‐associated proteins (MAPs) was examined, using purified porcine MAP1B and MAP2. MAP1B has a…”
Get full text

Phosphorylation of tau by glycogen synthase kinase 3beta affects the ability of tau to promote microtubule self-assembly by Utton, M A, Vandecandelaere, A, Wagner, U, Reynolds, C H, Gibb, G M, Miller, C C, Bayley, P M, Anderton, B H

“…To study the effects of phosphorylation by glycogen synthase kinase-3beta (GSK-3beta) on the ability of the microtubule-associated protein tau to promote…”
Get full text

The Slow Axonal Transport of the Microtubule-Associated Protein Tau and the Transport Rates of Different Isoforms and Mutants in Cultured Neurons by Utton, Michelle A, Connell, James, Asuni, Ayodeji A, van Slegtenhorst, Marjon, Hutton, Michael, de Silva, Rohan, Lees, Andrew J, Miller, Chris C. J, Anderton, Brian H

“…We demonstrate that the microtubule-associated protein tau, in the form of enhanced green fluorescent protein (EGFP) tau, is transported along axons of neurons…”
Get full text

301 Glycogen synthase kinase-3 and the phosphorylation of tau and APP by Anderton, B.H., Aplin, A.E., Bayley, P.M., Brion, J.-P., Davis, D.R., Gallo, J.-M., Gibb, G.M., Hanger, D.P., Jacobson, J.S., Lovestone, S., Reynolds, C.H., Utton, M., Vandecandelaere, A.

Get full text

DOMESTIC CONCENTRATION AND INTERNATIONAL TRADE: I. Introduction by Utton, M A

“…STUDIES of market structure and of structure-performance relationships have traditionally placed particular emphasis on market concentration. The level of…”
Get full text