Search Results - "Utsumi, H"
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Safety and efficacy of nivolumab and standard chemotherapy drug combination in patients with advanced non-small-cell lung cancer: a four arms phase Ib study
Published in Annals of oncology (01-12-2016)“…In this phase Ib study, four combination therapies of nivolumab 10 mg/kg and standard chemotherapy (cisplatin/gemcitabine, cisplatin/pemetrexed,…”
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Neurotransmitters, psychotropic drugs and microglia: clinical implications for psychiatry
Published in Current medicinal chemistry (2013)“…Psychiatric disorders have long and dominantly been regarded to be induced by disturbances of neuronal networks including synapses and neurotransmitters. Thus,…”
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Anti-Inflammatory properties of antipsychotics via microglia modulations: are antipsychotics a 'fire extinguisher' in the brain of schizophrenia?
Published in Mini reviews in medicinal chemistry (01-06-2011)“…Schizophrenia is one of the most severe psychiatric diseases noted for its chronic and often debilitating processes; affecting approximately 1% of the world's…”
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Spin dynamics of an individual Cr atom in a semiconductor quantum dot under optical excitation
Published in Applied physics letters (01-08-2016)“…We studied the spin dynamics of a Cr atom incorporated in a II-VI semiconductor quantum dot using photon correlation techniques. We used recently developed…”
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High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells
Published in Diabetes (New York, N.Y.) (01-11-2000)“…High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in…”
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Quantitative determination of OH radical generation and its cytotoxicity induced by TiO2-UVA treatment
Published in Toxicology in vitro (01-10-2002)Get full text
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Taste disorders in myasthenia gravis: a multicenter cooperative study
Published in European journal of neurology (01-01-2013)“…Background and purpose: The purpose of the present study was to investigate the prevalence and clinical characteristics of taste disorders in patients with…”
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Oxidative stress measurement by in vivo electron spin resonance spectroscopy in rats with streptozotocin-induced diabetes
Published in Diabetologia (01-11-1998)“…Enhanced oxidative stress in diabetic patients may contribute to the pathogenesis of diabetic angiopathy. We have recently developed a method to determine the…”
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Experimental Derivation of Relative Biological Effectiveness of A-Bomb Neutrons in Hiroshima and Nagasaki and Implications for Risk Assessment
Published in Radiation research (01-07-2008)“…Sasaki, M. S., Nomura, T., Ejima, Y., Utsumi, H., Endo, S., Saito, I., Itoh, T. and Hoshi, M. Experimental Derivation of Relative Biological Effectiveness of…”
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Inhibition of erythropoietin signalling destroys xenografts of ovarian and uterine cancers in nude mice
Published in British journal of cancer (23-03-2001)“…We have recently shown that malignant tumours from the ovary and uterus expressed erythropoietin (Epo) and its receptor (EpoR), and that deprivation of Epo…”
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Diffusion studies of redox-sensitive nitroxyl spin probes through bilayer lipid membranes using 300 MHz electron spin resonance spectrometer
Published in Biofizika (01-01-2015)“…Electron spin resonance (ESR) studies were carried out for 14N-labeled deuterated 3-methoxy-carbonyl-2,2,5,5-tetramethyl-pyrrolidine-1-oxyl (MC-PROXYL) and…”
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A possible target of antioxidative therapy for diabetic vascular complications-vascular NAD(P)H oxidase
Published in Current medicinal chemistry (01-09-2003)“…A growing body of evidence has shown that oxidative stress may be involved in the development of vascular complications associated with diabetes. However, the…”
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Frontal hypoperfusion as a possible participation of ischemic changes in ad patients
Published in Journal of the neurological sciences (2009)Get full text
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Estrogenic Activities of 517 Chemicals by Yeast Two-Hybrid Assay
Published in Journal of Health Science (2000)“…One of the urgent tasks in understanding endocrine disruptors (EDs) is to compile a list of suspected substances among the huge number of chemicals by using…”
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A kinetic study of enhancing effect by phenolic compounds on the hydroxyl radical generation during ozonation
Published in Water science and technology (01-01-2004)“…Ozone decomposition in aqueous solution proceeds through a radical type chain mechanism. These reactions involve the very reactive and catalytic intermediates…”
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Toxicity assessment of 255 chemicals to pure cultured nitrifying bacteria using biosensor
Published in Water science and technology (01-01-2002)“…The bioassay has been attracting attention as a method of toxicity assessments of micropollutants in the environment. In this study, we report the…”
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Antioxidant activity of nitroxide radicals in lipid peroxidation of rat liver microsomes
Published in Archives of biochemistry and biophysics (01-01-1993)“…Inhibition of lipid peroxidation by nitroxide radicals in rat liver microsomes was studied using several nitroxide compounds which have various…”
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Requirement for Repair of DNA Double-Strand Breaks by Homologous Recombination in Split-Dose Recovery
Published in Radiation research (01-05-2001)“…Utsumi, H., Tano, K., Takata, M., Takeda, S. and Elkind, M. M. Requirement for Repair of DNA Double-Strand Breaks by Homologous Recombination in Split-Dose…”
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Inhibitory effects of D2 agonists by striatal injection on excessive release of dopamine and hyperactivity induced by Bay K 8644 in rats
Published in Neuroscience (2003)“…We investigated by means of behavioral and neurochemical studies the effects of either D(1) or D(2) agonist on excessive dopamine release and hyperactivity…”
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