Search Results - "Utpatel, Kirsten"
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Quantification of contrast agent uptake in the hepatobiliary phase helps to differentiate hepatocellular carcinoma grade
Published in Scientific reports (26-11-2021)“…This study aimed to assess the degree of differentiation of hepatocellular carcinoma (HCC) using Gd-EOB-DTPA-assisted magnetic resonance imaging (MRI) with T1…”
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MALDI Mass Spectrometry Imaging for the Distinction of Adenocarcinomas of the Pancreas and Biliary Tree
Published in Molecules (Basel, Switzerland) (27-05-2022)“…Pancreatic ductal adenocarcinoma and cholangiocarcinoma constitute two aggressive tumor types that originate from the epithelial lining of the excretory ducts…”
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Staging more important than grading? Evaluation of malignancy grading, depth of invasion, and resection margins in oral squamous cell carcinoma
Published in Clinical oral investigations (01-03-2021)“…Objectives The present study evaluated the predictive value of staging and grading parameters concerning the presence of lymph-node metastases, overall…”
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Leishmania donovani infection mimicking ulcerative colitis in an immuno-competent patient
Published in International journal of infectious diseases (01-10-2024)“…•Visceral leishmaniasis can imitate chronic inflammatory bowel diseases.•Manifestation is possible in the entire gastrointestinal tract.•PCR from peripheral…”
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Simulated Microgravity Influences VEGF, MAPK, and PAM Signaling in Prostate Cancer Cells
Published in International journal of molecular sciences (13-02-2020)“…Prostate cancer is one of the leading causes of cancer mortality in men worldwide. An unusual but unique environment for studying tumor cell processes is…”
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PI3K: A master regulator of brain metastasis‐promoting macrophages/microglia
Published in Glia (01-11-2018)“…Mutations and activation of the PI3K signaling pathway in breast cancer cells have been linked to brain metastases. However, here we describe that in some…”
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Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis
Published in BMC cancer (09-11-2023)“…Upregulation of the mitogen-activated protein kinase (MAPK) cascade is common in hepatocellular carcinoma (HCC). Neuroblastoma RAS viral oncogene homolog…”
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Liver fibrosis and Gd-EOB-DTPA-enhanced MRI: A histopathologic correlation
Published in Scientific reports (19-10-2015)“…Gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) is a hepatocyte-specific MRI contrast agent. Because the hepatic uptake of Gd-EOB-DTPA…”
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Oncogene-dependent function of BRG1 in hepatocarcinogenesis
Published in Cell death & disease (04-02-2020)“…Hepatocellular carcinoma (HCC) is the major type of primary liver cancer. Genomic studies have revealed that HCC is a heterogeneous disease with multiple…”
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Hepatic Bone Morphogenetic Protein and Activin Membrane-Bound Inhibitor Levels Decline in Hepatitis C but Are Not Associated with Progression of Hepatocellular Carcinoma
Published in Biomedicines (19-10-2024)“…Bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) is an antagonist of transforming growth factor (TGF)-β type 1 signaling. BAMBI…”
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Chemerin and Chemokine-like Receptor 1 Expression Are Associated with Hepatocellular Carcinoma Progression in European Patients
Published in Biomedicines (01-03-2023)“…The chemoattractant protein chemerin is protective in experimental hepatocellular carcinoma (HCC), and high expression in HCC tissues of Asian patients was…”
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The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease
Published in Journal of experimental & clinical cancer research (03-06-2022)“…Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive primary liver tumor with increasing incidence worldwide, dismal prognosis, and few therapeutic…”
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Gd-EOB-DTPA-enhanced MR relaxometry for the detection and staging of liver fibrosis
Published in Scientific reports (27-01-2017)“…Gd-EOB-DTPA, a liver-specific contrast agent with T1-shortening effects, is routinely used in clinical routine for detection and characterization of focal…”
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Case Report: Extramedullary Acute Promyelocytic Leukemia: An Unusual Case and Mini-Review of the Literature
Published in Frontiers in oncology (25-05-2022)“…Acute promyelocytic leukemia (APL) constitutes a serious hematological emergency necessitating rapid diagnosis and therapy to prevent lethal bleedings…”
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Analysis of Luminex-based Algorithms to Define Unacceptable HLA Antibodies in CDC-crossmatch Negative Kidney Transplant Recipients
Published in Transplantation (01-06-2018)“…BACKGROUNDHLA-specific antibodies detected by solid phase assays are increasingly used to define unacceptable HLA antigen mismatches (UAM) before renal…”
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The Effects of Shear Force-Based Processing of Lipoaspirates on White Adipose Tissue and the Differentiation Potential of Adipose Derived Stem Cells
Published in Cells (Basel, Switzerland) (01-08-2022)“…Autologous lipotransfer is a promising method for tissue regeneration, because white adipose tissue contains a heterogeneous cell population, including…”
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Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver
Published in Oncotarget (30-04-2015)“…Activation of the PI3K and Yes-associated protein (Yap) signaling pathways has been independently reported in human hepatocellular carcinoma (HCC). However,…”
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RASSF1A independence and early galectin‐1 upregulation in PIK3CA‐induced hepatocarcinogenesis: new therapeutic venues
Published in Molecular oncology (01-03-2022)“…Aberrant activation of the phosphoinositide 3‐kinase (PI3K)/AKT/mTOR and Ras/mitogen‐activated protein kinase (MAPK) pathways is a hallmark of…”
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MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment
Published in Cell death & disease (11-02-2019)“…PD901, a MEK inhibitor, has been demonstrated of therapeutic efficacy against cholangiocarcinoma (CCA) harboring K-Ras oncogenic mutations. However, most CCA…”
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