Search Results - "Uthus, Eric O."

DNA methylation, cancer susceptibility, and nutrient interactions by Davis, Cindy D, Uthus, Eric O

“…DNA methylation is an important epigenetic mechanism of transcriptional control. DNA methylation plays an essential role in maintaining cellular function, and…”
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Prenatal low-protein and postnatal high-fat diets induce rapid adipose tissue growth by inducing Igf2 expression in Sprague Dawley rat offspring by Claycombe, Kate J, Uthus, Eric O, Roemmich, James N, Johnson, Luann K, Johnson, W Thomas

“…Maternal low-protein diets result in lower birth weight followed by accelerated catch-up growth that is accompanied by the development of obesity and glucose…”
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Determinants of selenium status in healthy adults by Combs, Jr, Gerald F, Watts, Jennifer C, Jackson, Matthew I, Johnson, LuAnn K, Zeng, Huawei, Scheett, Angela J, Uthus, Eric O, Schomburg, Lutz, Hoeg, Antonia, Hoefig, Carolin S, Davis, Cindy D, Milner, John A

“…Selenium (Se) status in non-deficient subjects is typically assessed by the Se contents of plasma/serum. That pool comprises two functional, specific…”
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Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats by Davis, Cindy D, Uthus, Eric O

“…Several observations suggest a role for DNA methylation in cancer pathogenesis. Although both selenium and folate deficiency have been shown to cause global…”
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Methionine flux to transsulfuration is enhanced in the long living Ames dwarf mouse by Uthus, Eric O., Brown-Borg, Holly M.

“…Long-lived Ames dwarf mice lack growth hormone, prolactin, and thyroid stimulating hormone. Additionally the dwarf mice have enzyme activities and levels that…”
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Mechanistic aspects of the interaction between selenium and arsenic by Zeng, Huawei, Uthus, Eric O., Combs, Gerald F.

“…Selenium is an essential trace element for humans and other animals, and there is mounting evidence for the efficacy of certain forms of selenium as…”
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Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon by Davis, C D, Uthus, E O, Finley, J W

“…Selenium is an essential trace element for human health, and it has received considerable attention for its possible role as an anticarcinogenic agent. The…”
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Nickel deficiency diminishes sperm quantity and movement in rats by Yokoi, Katsuhiko, Uthus, Eric O, Nielsen, Forrest H

“…Early studies on nickel essentiality with rats and goats indicated that nickel deprivation impaired reproductive performance. Nickel also has been found to…”
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Validation of DNA Methylation Patterns: Potential Biomarker for Heritable Risk of Preeclampsia by Wright, Michelle L., Anderson, Cindy M., Uthus, Eric. O., Ohm, Joyce E.

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Growth hormone alters methionine and glutathione metabolism in Ames dwarf mice by Brown-Borg, Holly M., Rakoczy, Sharlene G., Uthus, Eric O.

“…Reduced signaling of the growth hormone (GH)/insulin-like growth factor-1(IGF-1)/insulin pathway is associated with extended life span in several species. Ames…”
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Dietary selenomethionine increases exon-specific DNA methylation of the p53 gene in rat liver and colon mucosa by Zeng, Huawei, Yan, Lin, Cheng, Wen-Hsing, Uthus, Eric O

“…The regulation of site-specific DNA methylation of tumor suppressor genes has been considered as a leading mechanism by which certain nutrients exert their…”
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Determination of the specific activities of methionine sulfoxide reductase A and B by capillary electrophoresis by Uthus, Eric O.

“…A capillary electrophoresis (CE) method for the determination of methionine sulfoxide reductase A and methionine sulfoxide reductase B activities in mouse…”
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Obesity reduces methionine sulphoxide reductase activity in visceral adipose tissue by Uthus, Eric O, Picklo, Sr, Matthew J

“…Visceral obesity is linked to insulin resistance and cardiovascular disease. A recent genetic study indicated that the gene locus for the anti-oxidant defense…”
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Dietary selenium affects homocysteine metabolism differently in Fisher-344 rats and CD-1 mice by Uthus, Eric O, Ross, Sharon A

“…In our previous work with rats, plasma and tissue homocysteine concentrations were decreased by selenium deprivation. The purpose of this study was to follow…”
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Effect of dietary nickel deprivation on vision, olfaction, and taste in rats by Yokoi, Katsuhiko, Uthus, Eric O., Penland, James G., Nielsen, Forrest H.

“…Early studies on dietary nickel deprivation found decreased reproduction rate in pigs and decreased insemination and conception rates in goats. Studies from…”
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Dietary Selenium (Se) and Copper (Cu) Interact to Affect Homocysteine Metabolism in Rats by Uthus, Eric O, Ross, Sharon

“…Previously, we reported that both Se deficiency and Cu deficiency decreased plasma homocysteine (pHcys) and increased plasma glutathione (pGSH) in rats. We…”
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Dietary selenite and azadeoxycytidine treatments affect dimethylhydrazine-induced aberrant crypt formation in rat colon and DNA methylation in HT-29 cells by Davis, Cindy D, Uthus, Eric O

“…Several observations implicate a role for altered DNA methylation in cancer pathogenesis. The global level of DNA methylation is generally lower; however, DNA…”
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Copper deficiency decreases plasma homocysteine in rats by Uthus, Eric O, Reeves, Philip G, Saari, Jack T

“…The purpose of this study was to determine the effects of copper deficiency on key aspects of homocysteine metabolism that involve methionine recycling and…”
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Altered methionine metabolism in long living Ames dwarf mice by Uthus, Eric O., Brown-Borg, Holly M.

“…Ames dwarf mice (df/df) are deficient in growth hormone, prolactin, and thyroid-stimulating hormone and live significantly longer than their normal siblings…”
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Simultaneous detection of S-adenosylmethionine and S-adenosylhomocysteine in mouse and rat tissues by capillary electrophoresis by Uthus, Eric O

“…A capillary electrophoresis method for the determination of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in rat liver and kidney and mouse liver…”
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