Search Results - "Uthaisin, Chirapong"
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Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria
Published in The New England journal of medicine (22-09-2016)“…With the emergence and spread of artemisinin resistance, new therapies for malaria are needed. This study shows that the imidazolopiperazine KAF156, a new…”
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Inhibition of merozoite invasion and transient de-sequestration by sevuparin in humans with Plasmodium falciparum malaria
Published in PloS one (15-12-2017)“…Even with the best available treatment, the mortality from severe Plasmodium falciparum malaria remains high. Typical features at death are high parasite loads…”
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Pyronaridine–Artesunate versus Mefloquine plus Artesunate for Malaria
Published in The New England journal of medicine (05-04-2012)“…New therapies to treat malaria are needed. In this report, in which the authors studied 1271 patients from Asia and Africa, pyronaridine–artesunate was found…”
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Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial
Published in PloS one (18-01-2011)“…New antimalarials are needed for P. vivax and P. falciparum malaria. This study compared the efficacy and safety of pyronaridine-artesunate with that of…”
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Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre, parallel-group, randomised, controlled, phase 2 trial
Published in The Lancet infectious diseases (01-09-2023)“…Emergence of drug resistance demands novel antimalarial drugs with new mechanisms of action. We aimed to identify effective and well tolerated doses of…”
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EFFECT ON ROSETTE FORMATION OF ANTIBODIES TO DUFFY BINDING-LIKE 1 ALPHA DOMAIN OF PLASMODIUM FALCIPARUM ERYTHROCYTE MEMBRANE PROTEIN 1
Published in Southeast Asian journal of tropical medicine and public health (01-07-2016)“…The highly conserved Duffy binding-like domain 1 alpha (DBL1 alpha ) of Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) is central to…”
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