Search Results - "Usui, Soichiro"
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Clinical Diagnostic Criteria of Familial Hypercholesterolemia ― A Comparison of the Japan Atherosclerosis Society and Dutch Lipid Clinic Network Criteria
Published in Circulation Journal (25-05-2021)“…Background:This study is aimed to compare the efficacy of the 2017 Japan Atherosclerosis Society (JAS) familial hypercholesterolemia (FH) criteria, which…”
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Challenges of Precision Medicine for Atherosclerotic Cardiovascular Disease Based on Human Genome Information
Published in Journal of Atherosclerosis and Thrombosis (01-04-2021)“…Precision or personalized medicine is currently gaining a lot of attention. Clinical evidence for its effectiveness has been established based on randomized…”
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3
Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits
Published in Biological & pharmaceutical bulletin (01-05-2018)“…Selenoprotein P (SeP) is a selenium (Se)-rich extracellular protein. SeP is identified as a hepatokine, causing insulin resistance in type 2 diabetes. Thus,…”
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Validation of the 2022 Clinical Diagnostic Criteria of Familial Hypercholesterolemia in Japan
Published in Journal of Atherosclerosis and Thrombosis (01-05-2024)“…Aim: In 2022, the Japan Atherosclerosis Society (JAS) has revised its clinical diagnostic criteria of familial hypercholesterolemia (FH) and adopted the use of…”
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Low-Density Lipoprotein Cholesterol Level cannot be too Low: Considerations from Clinical Trials, Human Genetics, and Biology
Published in Journal of Atherosclerosis and Thrombosis (01-06-2020)“…LDL cholesterol is by far the best established “causal” cardiovascular risk. It is distributed normally, and the mean value ranges around 100~120 mg/dl. In…”
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Healthy lifestyle, lipoprotein (a) levels and the risk of coronary artery disease
Published in European journal of clinical investigation (01-01-2024)“…Background Lipoprotein (a) [Lp(a)] is associated with coronary artery disease (CAD). However, the role of healthy lifestyle against the risk of CAD with…”
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Impact of the severe familial hypercholesterolemia status on atherosclerotic risks
Published in Scientific reports (13-11-2023)“…Risks of atherosclerotic events substantially vary even among patients with familial hypercholesterolemia (FH) with extremely high risk based on life-long…”
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8
Optimal lesion size index to prevent conduction gap during pulmonary vein isolation
Published in Journal of cardiovascular electrophysiology (01-12-2018)“…Introduction A novel real‐time lesion size index (LSI) that incorporates contact force (CF), time, and power has been developed for safe and effective catheter…”
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9
The Assessment of Carotid Atherosclerotic Plaque among Young Patients with Familial Hypercholesterolemia
Published in Internal Medicine (01-11-2022)“…Objective Few data exist regarding when atherosclerotic changes occur among patients with familial hypercholesterolemia (FH). Carotid ultrasonography is a…”
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10
Effect of Catheter Ablation for Atrial Fibrillation in Heart Failure With Mid-Range or Preserved Ejection Fraction ― Pooled Analysis of the AF Frontier Ablation Registry and Hokuriku-Plus AF Registry
Published in Circulation Journal (23-06-2023)“…Background: A recent randomized trial demonstrated that catheter ablation for atrial fibrillation (AF) in patients with heart failure with reduced ejection…”
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11
Treatment with a Direct Oral Anticoagulant for Nonbacterial Thrombotic Endocarditis
Published in Internal Medicine (15-06-2021)“…We herein report a case of nonbacterial thrombotic endocarditis (NBTE) in a patient with previously undiagnosed lung cancer. A 62-year-old woman presented to…”
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12
Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells
Published in Scientific reports (15-01-2021)“…Cardiomyocyte regeneration is limited in adults. The adipose tissue-derived stromal vascular fraction (Ad-SVF) contains pluripotent stem cells that rarely…”
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Diabetes impairs the angiogenic capacity of human adipose-derived stem cells by reducing the CD271+ subpopulation in adipose tissue
Published in Biochemical and biophysical research communications (17-09-2019)“…Type 2 diabetes mellitus is an important risk factor for cardiovascular diseases (CVDs). Therapeutic angiogenesis using adipose-derived stem cells (ADSCs) is…”
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Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6
Published in PloS one (03-08-2017)“…Cardiac fibroblasts, together with cardiomyocytes, occupy the majority of cells in the myocardium and are involved in myocardial remodeling. The…”
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Effects of Longitudinal Changes in Anemia Status on Clinical Outcomes in Patients With Non-Valvular Atrial Fibrillation ― Analysis From the Hokuriku-Plus AF Registry
Published in Circulation Journal (27-08-2024)“…Background: Anemia, a common comorbidity in older patients with heart failure (HF) and atrial fibrillation (AF), is associated with an increased risk of…”
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Attainment of the low-density lipoprotein cholesterol treatment target and prognosis of heterozygous familial hypercholesterolemia
Published in Atherosclerosis (01-04-2023)“…No previous study has investigated the association between attainment of low-density lipoprotein (LDL) cholesterol treatment target and better prognosis in…”
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17
Autophagy plays an essential role in mediating regression of hypertrophy during unloading of the heart
Published in PloS one (07-01-2013)“…Autophagy is a bulk degradation mechanism for cytosolic proteins and organelles. The heart undergoes hypertrophy in response to mechanical load but hypertrophy…”
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Hypertrophic Cardiomyopathy Predicts Thromboembolism and Heart Failure in Patients With Nonvalvular Atrial Fibrillation ― A Prospective Analysis From the Hokuriku-Plus AF Registry
Published in Circulation Journal (24-11-2023)“…Background: The prognostic effect of concomitant hypertrophic cardiomyopathy (HCM) on adverse events in patients with atrial fibrillation (AF) has not been…”
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Important Role of Endogenous Nerve Growth Factor Receptor in the Pathogenesis of Hypoxia-Induced Pulmonary Hypertension in Mice
Published in International journal of molecular sciences (18-01-2023)“…Pulmonary arterial hypertension (PAH) remains a disease with poor prognosis; thus, a new mechanism for PAH treatment is necessary. Circulating nerve growth…”
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Inhibition of Endogenous Mst1 Prevents Apoptosis and Cardiac Dysfunction Without Affecting Cardiac Hypertrophy After Myocardial Infarction
Published in Circulation research (11-05-2007)“…Mammalian sterile 20–like kinase-1 (Mst1) plays an important role in mediating cardiac myocyte apoptosis in response to ischemia/reperfusion. Whether or not…”
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