Search Results - "Usoskin, Dmitry"
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Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
Published in Nature communications (08-03-2021)“…Distinct types of dorsal root ganglion sensory neurons may have unique contributions to chronic pain. Identification of primate sensory neuron types is…”
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Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
Published in Nature neuroscience (01-01-2015)“…Based on single cell RNA-sequencing of 622 adult mouse sensory neurons, Usoskin et al . performed unbiased classification to identify the cellular and…”
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Specialized cutaneous Schwann cells initiate pain sensation
Published in Science (American Association for the Advancement of Science) (16-08-2019)“…An essential prerequisite for the survival of an organism is the ability to detect and respond to aversive stimuli. Current belief is that noxious stimuli…”
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Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla
Published in Science (American Association for the Advancement of Science) (07-07-2017)“…Adrenaline is a fundamental circulating hormone for bodily responses to internal and external stressors. Chromaffin cells of the adrenal medulla (AM) represent…”
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miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes
Published in Science (American Association for the Advancement of Science) (16-06-2017)“…Nociception is protective and prevents tissue damage but can also facilitate chronic pain. Whether a general principle governs these two types of pain is…”
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Schwann Cell Precursors from Nerve Innervation Are a Cellular Origin of Melanocytes in Skin
Published in Cell (16-10-2009)“…Current opinion holds that pigment cells, melanocytes, are derived from neural crest cells produced at the dorsal neural tube and that migrate under…”
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UHRF1 Licensed Self‐Renewal of Active Adult Neural Stem Cells
Published in Stem cells (Dayton, Ohio) (01-11-2018)“…Adult neurogenesis in the brain continuously seeds new neurons throughout life, but how homeostasis of adult neural stem cells (NSCs) is maintained is…”
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Depletion of 26S Proteasomes in Mouse Brain Neurons Causes Neurodegeneration and Lewy-Like Inclusions Resembling Human Pale Bodies
Published in The Journal of neuroscience (13-08-2008)“…Ubiquitin-positive intraneuronal inclusions are a consistent feature of the major human neurodegenerative diseases, suggesting that dysfunction of the…”
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Transgenic expression of Cre recombinase from the tyrosine hydroxylase locus
Published in Genesis (New York, N.Y. : 2000) (01-10-2004)“…Catecholaminergic neurons are affected in several neurological and psychiatric diseases. Tyrosine hydroxylase (TH) is the first, rate‐limiting enzyme in…”
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En masse in vitro functional profiling of the axonal mechanosensitivity of sensory neurons
Published in Proceedings of the National Academy of Sciences - PNAS (14-09-2010)“…Perception of the environment relies on somatosensory neurons. Mechanosensory, proprioceptor and many nociceptor subtypes of these neurons have specific…”
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RETRACTED: Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule
Published in Cell (10-04-2014)“…Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer with marginal life expectancy. Based on the assumption that GBM cells gain functions…”
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Blocked MAP kinase activity selectively enhances neurotrophic growth responses
Published in Molecular and cellular neuroscience (01-02-2004)“…Bone morphogenetic proteins (BMPs) 4 and 6 as well as MEK inhibitors PD98059 and U0126 potentiate neurotrophin 3 (NT3)- and neurturin (NTN)-induced neurite…”
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Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control
Published in Nature neuroscience (01-10-2016)“…The sympathetic system maintains a physiological balance, adjusts bodily functions during daily living activities, and can activate stress responses. The…”
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Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation
Published in Nature neuroscience (04-11-2024)“…Abstract The versatility of somatosensation arises from heterogeneous dorsal root ganglion (DRG) neurons. However, soma transcriptomes of individual human…”
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Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule
Published in Cell (10-04-2014)“…Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer with marginal life expectancy. Based on the assumption that GBM cells gain functions…”
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Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule (Retraction of Vol 157, Pg 313, 2014)
Published in CELL (13-07-2017)Get full text
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Retraction Notice to: Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule
Published in Cell (13-07-2017)Get full text
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Essential role of Ret for defining non-peptidergic nociceptor phenotypes and functions in the adult mouse
Published in The European journal of neuroscience (01-04-2011)“…Transduction of pain following noxious stimuli is mediated by the activation of specialized ion channels and receptors expressed by nociceptive sensory…”
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Essential role of Ret for defining nonapeptidergic nociceptor phenotypes and functions in the adult mouse
Published in The European journal of neuroscience (01-04-2011)“…Transduction of pain following noxious stimuli is mediated by the activation of specialized ion channels and receptors expressed by nociceptive sensory…”
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