Search Results - "Uslu, Harun"

Effect of propolis on pyruvate kinase and superoxide dismutase activities in doxorubicin–induced tissue damage: Molecular docking analysis by Yilmaz, Seval, Kaya, Emre, Yonar, Harun, Uslu, Harun

“…This study aimed to investigate the effect of propolis on pyruvate kinase (PK) which is a key enzyme in glycolysis and superoxide dismutase (SOD), an…”
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A Series of New Hydrazone Derivatives: Synthesis, Molecular Docking and Anticholinesterase Activity Studies by Bozbey, İrem, Özdemir, Zeynep, Uslu, Harun, Özçelik, Azime Berna, Şenol, Fatma Sezer, Orhan, İlkay Erdoğan, Uysal, Mehtap

“…Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are known to be serine hydrolase enzymes responsible for the hydrolysis of acetylcholine (ACh),…”
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(E)-1-(4-Hydroxyphenyl)-3-(substituted-phenyl) prop-2-en-1-ones: Synthesis, In Vitro Cytotoxic Activity and Molecular Docking Studies by Sirka, Lütfiye, Doğan, Hacer, Bahar, Mehmet Refik, Çalışkan, Eray, Tekin, Suat, Uslu, Harun, Koran, Kenan, Sandal, Süleyman, Görgülü, Ahmet Orhan

“…A series of chalcone compounds (2–11) were designed and synthesized to determine their cytotoxic effects. The structures of 2–11 were fully characterized by…”
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In vivo, in vitro and in silico anticancer investigation of fullerene C60 on DMBA induced breast cancer in rats by Beyaz, Seda, Aslan, Abdullah, Gok, Ozlem, Uslu, Harun, Agca, Can Ali, Ozercan, Ibrahim Hanifi

“…The aim of the study was to determine the protective and therapeutic effect of fullerene C60 nanoparticle on DMBA-induced breast cancer in rats. In vitro cell…”
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Synthesis of novel Schiff bases using green chemistry techniques; antimicrobial, antioxidant, antiurease activity screening and molecular docking studies by Mermer, Arif, Demirbas, Neslihan, Uslu, Harun, Demirbas, Ahmet, Ceylan, Sule, Sirin, Yakup

“…Schiff base derivatives were synthesized in this study via conventional, microwave irradiation and ultrasound sonication methods. Optimization conditions were…”
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In vivo, in vitro and in silico anticancer investigation of fullerene C 60 on DMBA induced breast cancer in rats by Beyaz, Seda, Aslan, Abdullah, Gok, Ozlem, Uslu, Harun, Agca, Can Ali, Ozercan, Ibrahim Hanifi

“…The aim of the study was to determine the protective and therapeutic effect of fullerene C nanoparticle on DMBA-induced breast cancer in rats. In vitro cell…”
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In vitro effects of thirty‐eight cardiac drugs on human serum paraoxonase by Argan, Onur, Cikrikci, Kubra, Uslu, Harun, Gencer, Nahit

“…In this study, the effects of 38 commonly used cardiac drugs on the human paraoxonase (PON1) were investigated. PON1 was purified from human serum blood by…”
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Screening of phenolic components and antimicrobial properties of Iris persica L. subsp. persica extracts by in vitro and in silico methods by Unver, Tuba, Uslu, Harun, Gurhan, Ismet, Goktas, Bunyamin

“…The tendency toward natural herbal products has increased due to the antibiotic resistance developed by microorganisms and the severe side effects of…”
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Conventional and microwave prompted synthesis of aryl(alkyl)azole oximes, 1H-NMR spectroscopic determination of E/Z isomer ratio and HOMO-LUMO analysis by Bozbey, Irem, Uslu, Harun, Türkmenoğlu, Burçin, Özdemir, Zeynep, Karakurt, Arzu, Levent, Serkan

“…•Manuscript is research article. In this study, 12 oxime derivatives were synthesized by using with conventional method and microwave irradiation method. It…”
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Ellagic acid inhibits proinflammatory intermediary manufacture by suppressing NF-κB/Akt, VEGF and activating Nrf-2/Caspase-3 signaling pathways in rat testicular damage: a new way for testicular damage cure and in silico approach by Aslan, Abdullah, Gok, Ozlem, Beyaz, Seda, Uslu, Harun, Erman, Fazilet, Erman, Orhan, Baspinar, Serpil

“…Ellagic acid (EA) has protective effect on testicular damage and this natural compound decreases oxidative damage. The present study aims to examine the…”
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Synthesis, molecular modelling and biological activity of some pyridazinone derivatives as selective human monoamine oxidase-B inhibitors by Özdemir, Zeynep, Alagöz, Mehmet Abdullah, Uslu, Harun, Karakurt, Arzu, Erikci, Acelya, Ucar, Gulberk, Uysal, Mehtap

“…Since brain neurotransmitter levels are associated with the pathology of various neurodegenerative diseases like Parkinson and Alzheimer, monoamineoxidase…”
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Conventional and microwave prompted synthesis, antioxidant, anticholinesterase activity screening and molecular docking studies of new quinolone-triazole hybrids by Mermer, Arif, Demirbaş, Neslihan, Şirin, Yakup, Uslu, Harun, Özdemir, Zeynep, Demirbaş, Ahmet

“…[Display omitted] •Conventional and microwave prompted synthesis of new quinolone-triazole hybrids.•Screening antioxidant capacity of novel drug-like…”
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Synthesis of new piperazine‐oxadiazole derivatives and investigation of their anticancer activities by Uslu, Harun, Göktaş, Bünyamin, Osmaniye, Derya, Levent, Serkan, Göktaş, Sare Peçe, Sağlık Özkan, Begüm Nurpelin, Özkay, Yusuf, Benkli, Kadriye

“…•10 novel Piperazine-Oxadiazole hybrid derivatives were synthesized.•A good ADME profile were predicted for all the synthesized compounds.•The compound 4b…”
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Synthesis and spectroscopic characterizations of hexakis[(1-(4′-oxyphenyl)-3-(substituted-phenyl)prop-2-en-1-one)]cyclotriphosphazenes: their in vitro cytotoxic activity, theoretical analysis and molecular docking studies by Doğan, Hacer, Bahar, Mehmet Refik, Çalışkan, Eray, Tekin, Suat, Uslu, Harun, Akman, Feride, Koran, Kenan, Sandal, Süleyman, Görgülü, Ahmet Orhan

“…The hexachlorocyclotriphosphaze compound (N 3 P 3 Cl 6 , HCCP) was reacted with excess (E)-(1-(4′-oxyphenyl)-3-(substituted-phenyl)prop-2-en-1-ones (2-11) to…”
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Synthesis and Characterization of Propofol‐Like Compounds, Anticancer Activities and Investigation of Their Anesthetic Effects by Molecular Docking by Demirci, Serpil, Uslu, Harun, Mermer, Arif, Yesilay, Gamze, Betul Aydin, Zehra

“…This study was designed to synthesize hybrid molecules starting from 2,6‐diisopropyl aniline (1), which is similar to Propofol (2,6‐diisopropyl phenol), by…”
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Design, synthesis, in vitro, and in silico studies of 1,2,4-triazole-piperazine hybrid derivatives as potential MAO inhibitors by Uslu, Harun, Osmaniye, Derya, Sağlik, Begüm Nurpelin, Levent, Serkan, Özkay, Yusuf, Benkli, Kadriye, Kaplancikli, Zafer Asım

“…[Display omitted] •10 novel 1,2,4-Triazole-Piperazine hybrid derivatives were synthesized.•A good ADME profile were predicted for all the synthesized…”
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New (arylalkyl)azole derivatives showing anticonvulsant effects could have VGSC and/or GABAAR affinity according to molecular modeling studies by Sari, Suat, Karakurt, Arzu, Uslu, Harun, Kaynak, F. Betül, Çalış, Ünsal, Dalkara, Sevim

“…(Arylalkyl)azoles (AAAs) emerged as a novel class of antiepileptic agents with the invention of nafimidone and denzimol. Several AAA derivatives with potent…”
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ADME predictions and molecular docking study of some compounds and drugs as potential inhibitors of COVID-19 main protease: A virtual study as comparison of computational results by Uslu, Harun, Koparir, Pelin, Sarac, Kamuran, Karatepe, Arzu

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Synthesis and cytotoxicity studies on new pyrazolecontaining oxime ester derivatives by Karakurt, Arzu, Bozbey, Irem, Uslu, Harun, Sari, Suat, Özdemir, Zeynep, Şalva, Emine

“…Purpose: To synthesize a series of new 1-(2-naphthyl)-2-(1H-pyrazol-1-yl)ethanone oxime ester derivatives (5-12) with potential anticancer properties, and to…”
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New (arylalkyl)azole derivatives showing anticonvulsant effects could have VGSC and/or GABA A R affinity according to molecular modeling studies by Sari, Suat, Karakurt, Arzu, Uslu, Harun, Kaynak, F Betül, Çalış, Ünsal, Dalkara, Sevim

“…(Arylalkyl)azoles (AAAs) emerged as a novel class of antiepileptic agents with the invention of nafimidone and denzimol. Several AAA derivatives with potent…”
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