Search Results - "Usarek, Ewa"
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Validation of qPCR reference genes in lymphocytes from patients with amyotrophic lateral sclerosis
Published in PloS one (22-03-2017)“…Quantitative polymerase chain reaction (qPCR) is the most specific and reliable method for determination of mRNA gene expression. Crucial point for its…”
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Dynactin Deficiency in the CNS of Humans with Sporadic ALS and Mice with Genetically Determined Motor Neuron Degeneration
Published in Neurochemical research (01-12-2013)“…Dynactin is a complex motor protein involved in the retrograde axonal transport disturbances of which may lead to amyotrophic lateral sclerosis (ALS). Mice…”
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Targeting the expression of glutathione- and sulfate-dependent detoxification enzymes in HepG2 cells by oxygen in minimal and amino acid enriched medium
Published in Experimental and molecular pathology (01-02-2016)“…Cancer cells exhibit specific metabolism allowing them to survive and proliferate in various oxygen conditions and nutrients' availability. Hepatocytes are…”
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Kinesin expression in the central nervous system of humans and transgenic hSOD1G93A mice with amyotrophic lateral sclerosis
Published in Neuro-degenerative diseases (01-01-2013)“…Amyotrophic lateral sclerosis is a fatal motor neuron degenerative disease. Most cases are sporadic (SALS), and approximately 10% are familial (FALS) among…”
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Mice with Mutation in Dynein Heavy Chain 1 Do Not Share the Same Tau Expression Pattern with Mice with SOD1-Related Motor Neuron Disease
Published in Neurochemical research (01-06-2011)“…Due to controversy about the involvement of Dync1h1 mutation in pathogenesis of motor neuron disease, we investigated expression of tau protein in transgenic…”
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Changes in kinesin expression in the CNS of mice with dynein heavy chain 1 mutation
Published in Acta biochimica Polonica (01-01-2013)“…Dysfunction of fast axonal transport, vital for motor neurons, may lead to neurodegeneration. Anterograde transport is mediated by N-kinesins (KIFs), while…”
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Differences in glutathione S-transferase pi expression in transgenic mice with symptoms of neurodegeneration
Published in Acta biochimica Polonica (01-01-2011)“…Glutathione S-transferase pi (GST pi) is an enzyme involved in cell protection against toxic electrophiles and products of oxidative stress. GST pi expression…”
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Age-related changes in tau expression in transgenic mouse model of amyotrophic lateral sclerosis
Published in Neurochemical research (01-03-2007)“…The work is a continuation of studies on tau expression and alternative splicing in the central nervous system of transgenic mice harboring human SOD1 with…”
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A study of glutathione S-transferase pi expression in central nervous system of subjects with amyotrophic lateral sclerosis using RNA extraction from formalin-fixed, paraffin-embedded material
Published in Neurochemical research (01-08-2005)“…The expression of glutathione S-transferase pi (GST pi), an enzyme responsible for inactivation of a large variety of toxic compounds was studied in spinal…”
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Tau isoforms expression in transgenic mouse model of amyotrophic lateral sclerosis
Published in Neurochemical research (01-05-2006)“…Tau is a protein involved in regulation of microtubule stability, axonal differentiation and transport. Alteration of retrograde transport may lead to motor…”
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Expression of glutathione S-transferase isoenzymes in tongue and floor of mouth squamous cell carcinomas
Published in Polski merkuriusz lekarski (01-09-2007)“…Glutathione S-transferase (GST, EC 2.5.1.18) is one of the most important enzymes protecting cells against toxic, electrophilic compounds. It occurs in…”
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Expression of glutathione S-transferase isoenzymes in human gliomas
Published in Polski merkuriusz lekarski (01-06-2005)“…Glutathione S-transferase (GST) is a part of the most important enzymatic systems protecting organisms from toxic, electrophilic compounds. Expression of…”
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Expression of glutathione-S-transferase isoenzymes in larynx cancer
Published in Otolaryngologia Polska (2004)“…Carcinoma planoepitheliale of larynx is the most common cancer present in the upper part of the respiratory system. The molecular mechanism of this cancer…”
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