Search Results - "Usama, Syed Muhammad"

Doubly Strapped Zwitterionic NIR‐I and NIR‐II Heptamethine Cyanine Dyes for Bioconjugation and Fluorescence Imaging by Li, Dong‐Hao, Gamage, Rananjaya S., Oliver, Allen G., Patel, Nimit L., Muhammad Usama, Syed, Kalen, Joseph D., Schnermann, Martin J., Smith, Bradley D.

“…Heptamethine cyanine dyes enable deep tissue fluorescence imaging in the near infrared (NIR) window. Small molecule conjugates of the benchmark dye ZW800‐1…”
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Cytotoxicities of Tumor‐Seeking Dyes: Impact on Future Clinical Trials by Muhammad Usama, Syed, Gao, Zhe, Arancillo, Maritess, Burgess, Kevin

“…Heptamethine (Cy7) dyes with meso‐Cl substituents injected intravenously (iv) into mice accumulate in tumors and persist there over several days. We believe…”
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Fluorescent kinase inhibitors as probes in cancer by Usama, Syed Muhammad, Zhao, Bosheng, Burgess, Kevin

“…Fluorescent dyes attached to kinase inhibitors (KIs) can be used to probe kinases in vitro, in cells, and in vivo. Ideal characteristics of the dyes vary with…”
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Productive Manipulation of Cyanine Dye π‐Networks by Usama, Syed Muhammad, Thompson, Tye, Burgess, Kevin

“…Polymethine bridges in cyanine dyes may be constrained by setting them into edge‐fused ring systems, or extended by conjugation with carefully chosen…”
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Norcyanine-Carbamates Are Versatile Near-Infrared Fluorogenic Probes by Usama, Syed Muhammad, Inagaki, Fuyuki, Kobayashi, Hisataka, Schnermann, Martin J

“…Fluorogenic probes in the near-infrared (NIR) region have the potential to provide stimuli-dependent information in living organisms. Here, we describe a new…”
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Product state-resolved reactive scattering calculations using stair shaped grids in hyperspherical coordinates for the quantum wave packet method by Umer, Umair, Usama, Syed Muhammad, Zhao, Hailin, Sun, Zhigang

“…Efficient calculations of the quantum product state-resolved differential cross sections play a crucial role in unraveling the dynamics of a chemical reaction…”
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Re-irradiation for malignant glioma: Toward patient selection and defining treatment parameters for salvage by Shen, Colette J., MD, PhD, Kummerlowe, Megan N., BS, Redmond, Kristin J., MD, MPH, Martinez-Gutierrez, Juan Carlos, MD, Usama, Syed Muhammad, MBBS, Holdhoff, Matthias, MD, PhD, Grossman, Stuart A., MD, Laterra, John J., MD, PhD, Strowd, Roy E., MD, Kleinberg, Lawrence R., MD

“…Abstract Purpose Reirradiation for recurrent glioma remains controversial without knowledge of optimal patient selection, dose, fractionation, and normal…”
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Coumarins to Cyanines: Synthesis of Hemicyanines by Caldwell, Donald R, Usama, Syed Muhammad, Schnermann, Martin J

“…Near-infrared (NIR) emitting fluorophores are powerful tools for optical imaging. However, there are only a handful of broadly employed NIR-emitting scaffolds,…”
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Conjugation of Dasatinib with MHI‐148 Has a Significant Advantageous Effect in Viability Assays for Glioblastoma Cells by Usama, Syed Muhammad, Jiang, Zhengyang, Pflug, Kathryn, Sitcheran, Raquel, Burgess, Kevin

“…We hypothesized that conjugation of the near‐infrared dye MHI‐148 with the anti‐leukemia drug dasatinib might produce a potential theranostic for glioblastoma…”
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Protein labelling and albumin binding characteristics of the near-IR Cy7 fluorophore, QuatCy by Thavornpradit, Sopida, Usama, Syed Muhammad, Lin, Chen-Ming, Burgess, Kevin

“…Free cysteine residues react with QuatCy 1, by simply mixing the protein and dye in aqueous buffer at 37 °C. Another dye, MHI-148, can be used for a similar…”
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Cyanine Phototruncation Enables Spatiotemporal Cell Labeling by Fukushima, Hiroshi, Matikonda, Siddharth S., Usama, Syed Muhammad, Furusawa, Aki, Kato, Takuya, Štacková, Lenka, Klán, Petr, Kobayashi, Hisataka, Schnermann, Martin J.

“…Photoconvertible tracking strategies assess the dynamic migration of cell populations. Here we develop phototruncation-assisted cell tracking (PACT) and apply…”
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Site-Specific Labeling of Proteins with Near-IR Heptamethine Cyanine Dyes by Lin, Chen-Ming, Usama, Syed Muhammad, Burgess, Kevin

“…Convenient labeling of proteins is important for observing its function under physiological conditions. In tissues particularly, heptamethine cyanine dyes…”
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A zwitterionic near-infrared dye linked TrkC targeting agent for imaging metastatic breast cancer by Yang, Zhen, Usama, Syed Muhammad, Li, Feng, Burgess, Kevin, Li, Zheng

“…Much effort has been devoted to targeting agents for imaging and chemotherapy of tumors in cancer research, but there remain significant unmet needs in that…”
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Near-infrared duocarmycin photorelease from a Treg-targeted antibody-drug conjugate improves efficacy of PD-1 blockade in syngeneic murine tumor models by Fukushima, Hiroshi, Furusawa, Aki, Takao, Seiichiro, Thankarajan, Ebaston, Luciano, Michael P, Usama, Syed Muhammad, Kano, Makoto, Okuyama, Shuhei, Yamamoto, Hiroshi, Suzuki, Motofumi, Kano, Miyu, Choyke, Peter L, Schnermann, Martin J, Kobayashi, Hisataka

“…Regulatory T cells (Tregs) play a crucial role in mediating immunosuppression in the tumor microenvironment. Furthermore, Tregs contribute to the lack of…”
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Designing of Heating, Ventilation, and Air Conditioning (HVAC) System for Workshop Building in Hot and Humid Climatic Zone Using CLTD Method and HAP Analysis: A Comparison by Nadeem, Talha Bin, Ahmed, Ahsan, Naqvi, Asad A., Saad, Muhammad, Abbasi, Azan Ali, Arshad, Syed Muhammad Usama, Ahmed, Farooq

“…In recent times, global warming and climatic changes have caused significant increase in ambient temperatures, making heating, ventilation and air conditioning…”
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Targeted Dual-Modal PET/SPECT-NIR Imaging: From Building Blocks and Construction Strategies to Applications by Usama, Syed Muhammad, Marker, Sierra C, Hernandez Vargas, Servando, AghaAmiri, Solmaz, Ghosh, Sukhen C, Ikoma, Naruhiko, Tran Cao, Hop S, Schnermann, Martin J, Azhdarinia, Ali

“…Molecular imaging is an emerging non-invasive method to qualitatively and quantitively visualize and characterize biological processes. Among the imaging…”
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A Contemporary Review of Blood Transfusion in Critically Ill Patients by Yadav, Sumeet K, Hussein, Guleid, Liu, Bolun, Vojjala, Nikhil, Warsame, Mohamed, El Labban, Mohamad, Rauf, Ibtisam, Hassan, Mohamed, Zareen, Tashfia, Usama, Syed Muhammad, Zhang, Yaqi, Jain, Shika M, Surani, Salim R, Devulapally, Pavan, Bartlett, Brian, Khan, Syed Anjum, Jain, Nitesh Kumar

“…Blood transfusion is a common therapeutic intervention in hospitalized patients. There are numerous indications for transfusion, including anemia and…”
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Impact of Diabetes-related Self-management on Glycemic Control in Type II Diabetes Mellitus by Sayeed, Khalid A, Qayyum, Azwa, Jamshed, Fatima, Gill, Usman, Usama, Syed Muhammad, Asghar, Kanza, Tahir, Amber

“…Introduction: Self-care activities are behaviors adopted in order to enhance one’s health. Self-care behaviors and activities are studied in their role to…”
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Doubly Strapped Zwitterionic NIR‐I and NIR‐II Heptamethine Cyanine Dyes for Bioconjugation and Fluorescence Imaging by Li, Dong‐Hao, Gamage, Rananjaya S., Oliver, Allen G., Patel, Nimit L., Muhammad Usama, Syed, Kalen, Joseph D., Schnermann, Martin J., Smith, Bradley D.

“…Heptamethine cyanine dyes enable deep tissue fluorescence imaging in the near infrared (NIR) window. Small molecule conjugates of the benchmark dye ZW800‐1…”
Get full text

Sensorineural Hearing Loss and Its Relationship with Duration of Chelation Among Major β-Thalassemia Patients by Khan, Muhammad Ali, Khan, Mahrukh A, Seedat, Ahmed M, Khan, Maria, Khuwaja, Sana F, Kumar, Ram, Usama, Syed Muhammad, Fareed, Sundus

“…IntroductionThalassemia is a common genetic disorder worldwide, also occurring frequently in Karachi, Pakistan. Beta (β)-thalassemia major patients need…”
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