Search Results - "Usachev, Dmitry"
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GQIcombi application to subdue glioma via differentiation therapy
Published in Frontiers in oncology (26-06-2024)“…Current therapy protocols fail to cure high-grade gliomas and prevent recurrence. Therefore, novel approaches need to be developed. A re-programing of glioma…”
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A Combined Effect of G-Quadruplex and Neuro-Inducers as an Alternative Approach to Human Glioblastoma Therapy
Published in Frontiers in oncology (28-04-2022)“…Cancer cell reprogramming based on treatment with G-quadruplex, having antiproliferative power, along with small molecules able to develop iPSCs into neurons,…”
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Cerebellar anaplastic astrocytoma in adult patients: 15 consecutive cases from a single institution and literature review
Published in Journal of clinical neuroscience (01-09-2021)“…•Cerebellar anaplastic astrocytomas are extremely rare entities.•Incidence of IDH-1 mutation in cAA is higher than in cerebellar glioblastomas.•Patients with…”
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Covalent Bi-Modular Parallel and Antiparallel G-Quadruplex DNA Nanocostructs Reduce Viability of Patient Glioma Primary Cell Cultures
Published in International journal of molecular sciences (25-03-2021)“…G-quadruplex oligonucleotides (GQs) exhibit specific anti-proliferative activity in human cancer cell lines, and they can selectively inhibit the…”
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The Bi-(AID-1-T) G-Quadruplex Has a Janus Effect on Primary and Recurrent Gliomas: Anti-Proliferation and Pro-Migration
Published in Pharmaceuticals (Basel, Switzerland) (01-01-2024)“…High-grade gliomas are considered an incurable disease. Despite all the various therapy options available, patient survival remains low, and the tumor usually…”
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Rationale for double-barrel bypass for cerebral ischemia. Single-center study
Published in Brain & spine (2023)Get full text
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7
Cell-Population Dynamics in Diffuse Gliomas during Gliomagenesis and Its Impact on Patient Survival
Published in Cancers (26-12-2022)“…Diffuse gliomas continue to be an important problem in neuro-oncology. To solve it, studies have considered the issues of molecular pathogenesis from the…”
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RNA Aptamers for Theranostics of Glioblastoma of Human Brain
Published in Biochemistry (Moscow) (01-08-2021)“…Conventional approaches for studying and molecular typing of tumors include PCR, blotting, omics, immunocytochemistry, and immunohistochemistry. The last two…”
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Towards Aptamer-Targeted Drug Delivery to Brain Tumors: The Synthesis of Ramified Conjugates of an EGFR-Specific Aptamer with MMAE on a Cathepsin B-Cleavable Linker
Published in Pharmaceutics (11-11-2024)“…Background/Objectives: Targeted delivery of chemotherapeutic agents is a well-established approach to cancer therapy. Antibody–drug conjugates (ADCs) typically…”
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10
Brain structure segmentation and 3D printed individual craniometric rulers for cortex brain lesions
Published in Annals of 3D printed medicine (01-10-2022)“…Pre-operative visualization and three-dimensional (3D) printing have gained much interest in the state-of-the-medicine. This technical note describes the…”
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Internal Carotid Artery Injury in Transsphenoidal Surgery: Tenets for Its Avoidance and Refit-A Clinical Study
Published in Brain sciences (13-01-2021)“…One of the most serious/potentially fatal complications of transsphenoidal surgery (TSS) is internal carotid artery (ICA) injury. Of 6230 patients who…”
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Preoperative Stereotactic Radiosurgery of Brain Metastases: Preliminary Results
Published in Curēus (Palo Alto, CA) (26-12-2017)“… Preoperative stereotactic radiosurgery (pre-SRS) is a recent advancement in the strategy for brain metastasis (BM) management, and available data demonstrate…”
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Perifocal Zone of Brain Gliomas: Application of Diffusion Kurtosis and Perfusion MRI Values for Tumor Invasion Border Determination
Published in Cancers (15-05-2023)“…(1) Purpose: To determine the borders of malignant gliomas with diffusion kurtosis and perfusion MRI biomarkers. (2) Methods: In 50 high-grade glioma patients,…”
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Micro-Raman Characterization of Structural Features of High-k Stack Layer of SOI Nanowire Chip, Designed to Detect Circular RNA Associated with the Development of Glioma
Published in Molecules (Basel, Switzerland) (18-06-2021)“…The application of micro-Raman spectroscopy was used for characterization of structural features of the high-k stack (h-k) layer of “silicon-on-insulator”…”
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Operating experience and ways to improve the performance of the service water supply system at the Novovoronezh NPP II (Units 1 and 2)
Published in Nuclear energy and technology (10-11-2020)“…The operating experience of Novovoronezh NPP II-1 shows that, in the summer period, the temperature of the cooling water exceeds the design value: this…”
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Nanoribbon-Based Electronic Detection of a Glioma-Associated Circular miRNA
Published in Biosensors (Basel) (13-07-2021)“…Nanoribbon chips, based on “silicon-on-insulator” structures (SOI-NR chips), have been fabricated. These SOI-NR chips, whose surface was sensitized with…”
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Cerebral Revascularization Surgery: Surgical Indications and Strategies
Published in Brain & spine (2024)Get full text
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Intraoperative Hypercapnic Arterial Spin Labeling MRI In Surgical Revascularization
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19
Pearls and pitfalls in double-barrel STA-MCA bypass surgery for cerebral ischemia
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20
Effectiveness criteria and risk factors of surgical revascularization in Moya-Moya angiopathy: experience of 200 cases
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