Search Results - "Urwyler, Albert"
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Analgesic and Antihyperalgesic Properties of Propofol in a Human Pain Model
Published in Anesthesiology (Philadelphia) (01-08-2010)“…Propofol (Disoprivan, AstraZeneca AG, Zug, Switzerland) has long been considered to be nonanalgesic. However, accumulating evidence shows that propofol…”
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2
Molecular genetic testing for malignant hyperthermia susceptibility
Published in Anesthesiology (Philadelphia) (01-05-2004)“…For more than 30 yr, the in vitro contracture test (IVCT) was the only appropriate diagnostic tool for malignant hyperthermia (MH). After the introduction of…”
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3
B-lymphocytes from Malignant Hyperthermia-susceptible Patients Have an Increased Sensitivity to Skeletal Muscle Ryanodine Receptor Activators
Published in The Journal of biological chemistry (21-12-2001)“…Malignant hyperthemia (MH) is a pharmacogenetic disease triggered by volatile anesthetics and succinylcholine in genetically predisposed individuals. The…”
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4
Rare, Potentially Fatal, Poorly Understood Propofol Infusion Syndrome
Published in Clinics and practice (03-09-2012)“…We present the case of a 7-year old boy with traumatic brain injury who received propofol during 38 h. Thirty-six hours after cessation of propofol infusion…”
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5
Genotype-phenotype comparison of the Swiss malignant hyperthermia population
Published in Human mutation (01-10-2001)“…Malignant hyperthermia (MH) is a potentially lethal pharmacogenetic disease, triggered by inhalative anesthetics or depolarizing muscle relaxants in…”
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6
Identification of Novel Mutations in the Ryanodine-Receptor Gene (RYR1) in Malignant Hyperthermia: Genotype-Phenotype Correlation
Published in American journal of human genetics (01-03-1998)“…Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that is triggered in genetically predisposed individuals by common anesthetics and…”
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Malignant hyperthermia: presymptomatic screening and treatment 2011
Published in European journal of anaesthesiology (01-04-2011)Get full text
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8
BMI and malignant hyperthermia pathogenic ryanodine receptor type 1 sequence variants in Switzerland: A retrospective cohort analysis
Published in European journal of anaesthesiology (01-07-2021)“…Ryanodine receptor type 1 (RYR1) sequence variants are pathogenic for malignant hyperthermia. Variant carriers have a subtle increase in resting myoplasmic…”
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Consensus guidelines on perioperative management of malignant hyperthermia suspected or susceptible patients from the European Malignant Hyperthermia Group
Published in British journal of anaesthesia : BJA (01-01-2021)“…Malignant hyperthermia is a potentially fatal condition, in which genetically predisposed individuals develop a hypermetabolic reaction to potent inhalation…”
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10
Tropisetron blocks analgesic action of acetaminophen: A human pain model study
Published in Pain (Amsterdam) (01-06-2011)“…Because the mechanism underlying the analgesic action of acetaminophen remains unclear, we investigated the possible interaction of acetaminophen with central…”
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Effect of L-carnitine supplementation on the body carnitine pool, skeletal muscle energy metabolism and physical performance in male vegetarians
Published in European journal of nutrition (01-02-2016)“…PURPOSE: More than 95 % of the body carnitine is located in skeletal muscle, where it is essential for energy metabolism. Vegetarians ingest less carnitine and…”
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Increasing the number of diagnostic mutations in malignant hyperthermia
Published in Human mutation (01-04-2009)“…Malignant hyperthermia (MH) is an autosomal dominant disorder characterized by abnormal calcium homeostasis in skeletal muscle in response to triggering…”
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13
Resequencing array for gene variant detection in malignant hyperthermia and butyrylcholinestherase deficiency
Published in Neuromuscular disorders : NMD (01-05-2017)“…Highlights • A new array for full-length genotyping of RyR1, CACNA1S and BCHE genes is presented. • The arrays detected all the tested causative mutations for…”
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14
Contractile function and energy metabolism of skeletal muscle in rats with secondary carnitine deficiency
Published in American journal of physiology: endocrinology and metabolism (01-08-2015)“…The consequences of carnitine depletion upon metabolic and contractile characteristics of skeletal muscle remain largely unexplored. Therefore, we investigated…”
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High dose amino acid administration achieves an anabolic response in type 2 diabetic patients that is independent of glycaemic control: A randomized clinical trial
Published in Clinical nutrition (Edinburgh, Scotland) (01-08-2018)“…Summary Background & aims Surgical stress provokes protein catabolism and hyperglycaemia that is enhanced in patients with type 2 diabetes (T2DM), and…”
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16
Case Scenario: Increased End-tidal Carbon Dioxide: A Diagnostic Dilemma
Published in Anesthesiology (Philadelphia) (01-02-2010)Get full text
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Serious Complications Associated with External Intrathecal Catheters Used in Cancer Pain Patients: A Systematic Review and Meta-analysis
Published in Anesthesiology (Philadelphia) (01-12-2009)“…Potential risks of intrathecal catheters in cancer patients include infection, bleeding, and neurologic injury. A systematic review and a pooled analysis of…”
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18
Not Every Hypermetabolic State Is Due to Malignant Hyperthermia
Published in Anesthesia and analgesia (01-06-2007)Get full text
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19
All Valve Malfunctions Are Not the Same
Published in Anesthesiology (Philadelphia) (01-09-2010)Get full text
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20
Language difficulties in outpatients and their impact on a chronic pain unit in Northwest Switzerland
Published in Swiss medical weekly (01-05-2010)“…Many foreign patients attending our pain clinic are unable to understand one of the four Swiss national languages and are also unable to speak English…”
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