Search Results - "Ursuegui, Sylvain"

An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin by Ursuegui, Sylvain, Recher, Marion, Krężel, Wojciech, Wagner, Alain

“…Drugs, usually long acting and metabolically stable molecules, might be the source of adverse effects triggered by complex drug interactions, anaphylaxis and…”
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On the use of DNA as a linker in antibody-drug conjugates: synthesis, stability and in vitro potency by Dovgan, Igor, Ehkirch, Anthony, Lehot, Victor, Kuhn, Isabelle, Koniev, Oleksandr, Kolodych, Sergii, Hentz, Alexandre, Ripoll, Manon, Ursuegui, Sylvain, Nothisen, Marc, Cianférani, Sarah, Wagner, Alain

“…Here we present the synthesis and evaluation of antibody-drug conjugates (ADCs), for which antibody and drug are non-covalently connected using complementary…”
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Acyl Fluorides: Fast, Efficient, and Versatile Lysine-Based Protein Conjugation via Plug-and-Play Strategy by Dovgan, Igor, Ursuegui, Sylvain, Erb, Stéphane, Michel, Chloé, Kolodych, Sergii, Cianférani, Sarah, Wagner, Alain

“…We report a plug-and-play strategy for the preparation of functionally enhanced antibodies with a defined average degree of conjugation (DoC). The first stage…”
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Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles by Lehot, Victor, Neuberg, Patrick, Ripoll, Manon, Daubeuf, François, Erb, Stéphane, Dovgan, Igor, Ursuegui, Sylvain, Cianférani, Sarah, Kichler, Antoine, Chaubet, Guilhem, Wagner, Alain

“…Despite their clinical success, Antibody-Drug Conjugates (ADCs) are still limited to the delivery of a handful of cytotoxic small-molecule payloads. Adaptation…”
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Multiplex Digital PCR for the simultaneous quantification of a miRNA panel by Busato, Florence, Ursuegui, Sylvain, Deleuze, Jean-François, Tost, Jorg

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Droplet Surface Immunoassay by Relocation (D-SIRe) for High-Throughput Analysis of Cytosolic Proteins at the Single-Cell Level by Dufossez, Robin, Ursuegui, Sylvain, Baudrey, Stephanie, Pernod, Ketty, Mouftakhir, Safae, Oulad-Abdelghani, Mustapha, Mosser, Michel, Chaubet, Guilhem, Ryckelynck, Michael, Wagner, Alain

“…Enzyme-linked immunosorbent assay (ELISA) is a central analytic method in biological science for the detection of proteins. Introduction of droplet-based…”
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Microfluidic Droplet Stabilization via SPAAC Promoted Antibody Conjugation at the Water/Oil Interface by Dufossez, Robin, Krafft, Marie-Pierre, Ursuegui, Sylvain, Mosser, Michel, Mouftakhir, Safae, Pernod, Ketty, Chaubet, Guilhem, Ryckelynck, Michael, Wagner, Alain

“…Droplet-based microfluidics is leading the development of miniaturized, rapid, and sensitive version of enzyme-linked immunosorbent assays (ELISAs), a central…”
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Supramolecular Bioconjugation Strategy for Antibody-Targeted Delivery of siRNA by Ripoll, Manon, Cahuzac, Héloïse, Dovgan, Igor, Ursuegui, Sylvain, Neuberg, Patrick, Erb, Stephane, Cianférani, Sarah, Kichler, Antoine, Remy, Jean-Serge, Wagner, Alain

“…RNA interference is a widely used biological process by which double-stranded RNA induces sequence-specific gene silencing by targeting mRNA for degradation…”
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Automated linkage of proteins and payloads producing monodisperse conjugates by Dovgan, Igor, Hentz, Alexandre, Koniev, Oleksandr, Ehkirch, Anthony, Hessmann, Steve, Ursuegui, Sylvain, Delacroix, Sébastien, Riomet, Margaux, Taran, Frédéric, Cianférani, Sarah, Kolodych, Sergii, Wagner, Alain

“…Controlled protein functionalization holds great promise for a wide variety of applications. However, despite intensive research, the stoichiometry of the…”
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Manniindole, an indole derivative from the roots of Anonidium mannii and combined antischistosomal and enzymatic activities by Toussi Matchi, Josette Linda, Tchamo Noungoue, Diderot, Kuhn, Isabelle, Boissier, Jérôme, Tchouankeu, Jean Claude, Nothisen, Marc, Chaubet, Guilhem, Garnier, Delphine, Ursuegui, Sylvain, Ngouela, Silvère Augustin, Wagner, Alain

“…A new alkaloid, manniindole 1, together with four known compounds: aristolactam AII 2, aristolactam BII 3, piperolactam D 4 and polycarpol 5 were isolated from…”
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Antischistosomal evaluation of stem bark's extract and chemical constituents from anonidium mannii against schistosoma mansoni by Toussi Matchi, Josette, Noungoue, Diderot, Chaubet, Guilhem, Boissier, Jérôme, Kuhn, Isabelle, Tchouankeu, Jean, Nothisen, Marc, Ursuegui, Sylvain, Ngouela, Silvère, Wagner, Alain

“…Context: Anonidium mannii (Annonaceae) has been traditionally used in Africa to treat stomach aches, schistosomiasis, and many other illnesses. However, few…”
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Manniindole, an indole derivative from the roots of Anonidium mannii and combined antischistosomal and enzymatic activities by Toussi Matchi, Josette Linda, Tchamo Noungoue, Diderot, Kuhn, Isabelle, Boissier, Jérôme, Tchouankeu, Jean Claude, Nothisen, Marc, Chaubet, Guilhem, Garnier, Delphine, Ursuegui, Sylvain, Ngouela, Silvère Augustin, Wagner, Alain

“…A new alkaloid, manniindole , together with four known compounds: aristolactam AII , aristolactam BII , piperolactam D and polycarpol were isolated from the…”
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Biotin-conjugated N-methylisatoic anhydride: a chemical tool for nucleic acid separation by selective 2'-hydroxyl acylation of RNA by Ursuegui, S, Chivot, N, Moutin, S, Burr, A, Fossey, C, Cailly, T, Laayoun, A, Fabis, F, Laurent, A

“…An isatoic anhydride derivative conjugated to a biotin and a disulfide linker was specifically designed for the separation of nucleic acids. Starting from a…”
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