Search Results - "Urquhart, A. J."

Centrobin regulates the assembly of functional mitotic spindles by Jeffery, J M, Urquhart, A J, Subramaniam, V N, Parton, R G, Khanna, K K

“…The proper function of the spindle is crucial to the high fidelity of chromosome segregation and is indispensable for tumor suppression in humans. Centrobin is…”
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Recent advances in compartmentalized synthetic architectures as drug carriers, cell mimics and artificial organelles by York-Duran, M.J., Godoy-Gallardo, M., Labay, C., Urquhart, A.J., Andresen, T.L., Hosta-Rigau, L.

“…Carriers containing multiple compartments have recently emerged as a new platform with enormous potential in the fields of drug delivery and cell mimicry…”
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Primer binding site mutations affecting the typing of STR loci contained within the AMPFlSTR® SGM Plus kit by CLAYTON, T. M, HILL, S. M, DENTON, L. A, WATSON, S. K, URQUHART, A. J

“…The Forensic Science Service carries out human identification and familial investigations using the AMPFlSTR SGM Plus kit (PE Biosystems, Warrington, England)…”
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Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTS1 receptor by Gould, S.J. (The Johns Hopkins University School of Medicine, Baltimore, MD.), Kalish, J.E, Morrell, J.C, Bjorkman, J, Urquhart, A.J, Crane, D.I

“…Import of newly synthesized PTS1 proteins into the peroxisome requires the PTS1 receptor (Pex5p), a predominantly cytoplasmic protein that cycles between the…”
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High Throughput Surface Characterisation of a Combinatorial Material Library by Urquhart, A. J., Anderson, D. G., Taylor, M., Alexander, M. R., Langer, R., Davies, M. C.

“…The figure shows a schematic representing the information that can be obtained from the surface of each polymer sample within the microarrayed library. High…”
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Short tandem repeat typing of bodies from a mass disaster: high success rate and characteristic amplification patterns in highly degraded samples by Whitaker, J P, Clayton, T M, Urquhart, A J, Millican, E S, Downes, T J, Kimpton, C P, Gill, P

“…We have used a PCR-based DNA-typing method, involving the coamplification of four tetrameric short tandem repeat loci, in the analysis of a large number of…”
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New reference allelic ladders to improve allelic designation in a multiplex STR system by Griffiths, R A, Barber, M D, Johnson, P E, Gillbard, S M, Haywood, M D, Smith, C D, Arnold, J, Burke, T, Urquhart, A J, Gill, P

“…This paper reports the composition of a new reference allelic ladder mixture for use with a multiplex DNA profiling system consisting of six short tandem…”
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Acute intermittent porphyria caused by defective splicing of porphobilinogen deaminase RNA: a synonymous codon mutation at -22 bp from the 5' splice site causes skipping of exon 3 by Llewellyn, D H, Scobie, G A, Urquhart, A J, Whatley, S D, Roberts, A G, Harrison, P R, Elder, G H

“…Acute intermittent porphyria (AIP) results from mutations in the porphobilinogen deaminase (PBG) gene. Three of 14 randomly selected, unrelated patients with…”
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Interaction of Pex5p, the Type 1 Peroxisome Targeting Signal Receptor, with the Peroxisomal Membrane Proteins Pex14p and Pex13p by Urquhart, Aaron J., Kennedy, Derek, Gould, Stephen J., Crane, Denis I.

“…Pex5p, a receptor for peroxisomal matrix proteins with a type 1 peroxisome targeting signal (PTS1), has been proposed to cycle from the cytoplasm to the…”
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Acute intermittent porphyria caused by a C----T mutation that produces a stop codon in the porphobilinogen deaminase gene by Scobie, G A, Llewellyn, D H, Urquhart, A J, Smyth, S J, Kalsheker, N A, Harrison, P R, Elder, G H

“…A mutation of the porphobilinogen (PBG) deaminase gene that produces the cross-reacting immunological material (CRIM)-negative type of acute intermittent…”
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Uroporphyria produced in mice by 20-methylcholanthrene and 5-aminolaevulinic acid by Urquhart, A J, Elder, G H, Roberts, A G, Lambrecht, R W, Sinclair, P R, Bement, W J, Gorman, N, Sinclair, J A

“…Iron-loaded male C57BL/6 mice allowed free access to an aqueous solution of 5-aminolaevulinic acid (ALA) (2 mg/ml) as their only drink, develop severe…”
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Uroporphyrin accumulation produced by halogenated biphenyls in chick-embryo hepatocytes. Reversal of the accumulation by piperonyl butoxide by Sinclair, P R, Bement, W J, Bonkovsky, H L, Lambrecht, R W, Frezza, J E, Sinclair, J F, Urquhart, A J, Elder, G H

“…Cultures of chick-embryo hepatocytes were used to study the mechanism by which 3,4,3',4'-tetrachlorobiphenyl and 2,4,5,3',4'-pentabromobiphenyl cause…”
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Hexachlorobenzene-induced oxygen activation by mouse liver microsomes: comparison with phenobarbitone and 20-methylcholanthrene by Urquhart, A J, Elder, G H

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Linkage disequilibrium between DNA polymorphisms within the porphobilinogen deaminase gene by Scobie, G A, Urquhart, A J, Elder, G H, Kalsheker, N A, Llewellyn, D H, Smyth, J, Harrison, P R

“…Three restriction fragment length polymorphisms (RFLPs) (MspI, PstI, ScrFI/BstNI) within the human porphobilinogen deaminase (PBG-D) gene have been studied in…”
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The most northerly practice in Canada. 1935 by Urquhart, J A

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Hepatic uroporphyrin accumulation and uroporphyrinogen decarboxylase activity in cultured chick-embryo hepatocytes and in Japanese quail (Coturnix coturnix japonica) and mice treated with polyhalogenated aromatic compounds by Lambrecht, R.W, Sinclair, P.R, Bement, W.J, Sinclair, J.F, Carpenter, H.M, Buhler, D.R, Urquhart, A.J, Elder, G.H

“…The relationship between hepatic uroporphyrin accumulation and uroporphyrinogen decarboxylase (EC 4.1.1.37) activity was investigated in cultured chick-embryo…”
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A Basis for Anomalous Band Patterns Encountered During DNA STR Profiling by Clayton, TM, Guest, JL, Urquhart, AJ, Gill, PD

“…Since 1995 the Forensic Science Service (FSS) has carried out DNA profiling of reference samples for the UK National DNA Database (1) and in forensic casework…”
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Alterations of uroporphyrinogen decarboxylase by chlorinated organics by Elder, G H, Roberts, A G, Urquhart, A J

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A highly discriminating octoplex short tandem repeat polymerase chain reaction system suitable for human individual identification by Oldroyd, N J, Urquhart, A J, Kimpton, C P, Millican, E S, Watson, S K, Downes, T, Gill, P D

“…Through the use of fluorescence-based polymerase chain reaction systems, a highly discriminating multiplex with the potential for individual identification has…”
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Mapping the Interactions among Biomaterials, Adsorbed Proteins, and Human Embryonic Stem Cells by Mei, Ying, Gerecht, Sharon, Taylor, Michael, Urquhart, Andrew J., Bogatyrev, Said R., Cho, Seung-Woo, Davies, Martyn C., Alexander, Morgan R., Langer, Robert S., Anderson, Daniel G.

“…An integrated high‐throughput polymer synthesis and rapid material/protein/cell interaction assays were developed to optimize stem cell microenvironments…”
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