Search Results - "Uriu, Koichiro"
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1
Ripply suppresses Tbx6 to induce dynamic-to-static conversion in somite segmentation
Published in Nature communications (13-04-2023)“…The metameric pattern of somites is created based on oscillatory expression of clock genes in presomitic mesoderm. However, the mechanism for converting the…”
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2
Complementary phase responses via functional differentiation of dual negative feedback loops
Published in PLoS computational biology (08-03-2021)“…Multiple feedback loops are often found in gene regulations for various cellular functions. In mammalian circadian clocks, oscillations of Period1 (Per1) and…”
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3
Orchestration of tissue shape changes and gene expression patterns in development
Published in Seminars in cell & developmental biology (30-09-2023)“…In development, tissue shape changes and gene expression patterns give rise to morphogenesis. Understanding tissue shape changes requires the analysis of…”
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4
Cell size homeostasis under the circadian regulation of cell division in cyanobacteria
Published in Journal of theoretical biology (21-11-2022)“…Bacterial cells maintain their characteristic cell size over many generations. Several rod-shaped bacteria, such as Escherichia coli and the cyanobacteria…”
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5
Information flow in the presence of cell mixing and signaling delays during embryonic development
Published in Seminars in cell & developmental biology (01-09-2019)“…Embryonic morphogenesis is organized by an interplay between intercellular signaling and cell movements. Both intercellular signaling and cell movement involve…”
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6
A saturated reaction in repressor synthesis creates a daytime dead zone in circadian clocks
Published in PLoS computational biology (01-02-2019)“…Negative feedback loops (NFLs) for circadian clocks include light-responsive reactions that allow the clocks to shift their phase depending on the timing of…”
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7
From local resynchronization to global pattern recovery in the zebrafish segmentation clock
Published in eLife (15-02-2021)“…Integrity of rhythmic spatial gene expression patterns in the vertebrate segmentation clock requires local synchronization between neighboring cells by…”
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8
Feedback loops interlocked at competitive binding sites amplify and facilitate genetic oscillations
Published in Journal of theoretical biology (07-09-2017)“…•BMAL1 circadian rhythm generation is studied.•Optimal ratio of dissociation constants amplifies BMAL1 oscillations.•Competitive and noncompetitive binding…”
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9
Computational Approaches to Developmental Patterning
Published in Science (American Association for the Advancement of Science) (13-04-2012)“…Computational approaches are breaking new ground in understanding how embryos form. Here, we discuss recent studies that couple precise measurements in the…”
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10
Random cell movement promotes synchronization of the segmentation clock
Published in Proceedings of the National Academy of Sciences - PNAS (16-03-2010)“…In vertebrate somitogenesis, the expression of segmentation clock genes oscillates and the oscillation is synchronized over nearby cells. Both experimental and…”
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11
Impacts of the feedback loop between sense-antisense RNAs in regulating circadian rhythms
Published in NPJ systems biology and applications (16-10-2024)“…Antisense transcripts are a unique group of non-coding RNAs and play regulatory roles in a variety of biological processes, including circadian rhythms. Per2AS…”
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12
Determining the impact of cell mixing on signaling during development
Published in Development, growth & differentiation (01-06-2017)“…Cell movement and intercellular signaling occur simultaneously to organize morphogenesis during embryonic development. Cell movement can cause relative…”
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13
Sample Size Allocation for Food Item Radiation Monitoring and Safety Inspection
Published in Risk analysis (01-03-2015)“…The objective of this study is to identify a procedure for determining sample size allocation for food radiation inspections of more than one food item to…”
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14
Examination of teaching data for Hobbing-Machine-Diagnosis system (Comparison of classification performance of helical gears and spur gears and comparison of matrix images by hobbing simulation and actual hobbing)
Published in Kikai Gakkai ronbunshū = Transactions of the Japan Society of Mechanical Engineers (2022)“…Various factors in hobbing processes affect profile and helix deviations of hobbed gears, which prevent problems on the hobbing machine from being analyzed…”
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15
Object Segmentation and Ground Truth in 3D Embryonic Imaging
Published in PloS one (22-06-2016)“…Many questions in developmental biology depend on measuring the position and movement of individual cells within developing embryos. Yet, tools that provide…”
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16
Effects of shaft angle on cutting tool parameters in internal gear skiving
Published in Journal of mechanical science and technology (01-12-2017)“…Gear skiving has received considerable attention because of its high productivity, particularly in internal gear cutting, and skiving cutter design methods…”
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17
Expression of gear-tooth-flank deviations for Hobbing-Machine-Diagnosis system (Learning-data collection through hobbing simulation and their compression with network representation)
Published in Kikai Gakkai ronbunshū = Transactions of the Japan Society of Mechanical Engineers (2021)“…A hobbed gear has pitch, profile, and helix deviations caused by various factors. However it is hard for even experts to specify which factors cause individual…”
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18
A framework for quantification and physical modeling of cell mixing applied to oscillator synchronization in vertebrate somitogenesis
Published in Biology open (15-08-2017)“…In development and disease, cells move as they exchange signals. One example is found in vertebrate development, during which the timing of segment formation…”
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Correction: Object Segmentation and Ground Truth in 3D Embryonic Imaging
Published in PloS one (16-08-2016)“…[This corrects the article DOI: 10.1371/journal.pone.0150853.]…”
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20
Optimal cellular mobility for synchronization arising from the gradual recovery of intercellular interactions
Published in Physical biology (01-06-2012)“…Cell movement and intercellular signaling occur simultaneously during the development of tissues, but little is known about how movement affects signaling…”
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