Search Results - "Uriac, P."

Intramolecular transesterification of depsides yields fluorescent 1H-isochromen-1-ones: Application as a chemical probe for lichen determination by Ferron, S., Jéhan, P., Guillory, X., Uriac, P.

“…The reactivity of eight purified depsides obtained from six european lichens and that display as 2-oxoalkyl chain in ortho-position of the ester bond was…”
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Polyamine sulfonamides with NMDA antagonist properties are potent calmodulin antagonists and cytotoxic agents by Seiler, N, Douaud, F, Renault, J, Delcros, J.-G, Havouis, R, Uriac, P, Moulinoux, J.-P

“…N 1-Dansylspermine and related sulfonamides of the natural polyamines are very potent blockers of NMDA-type glutamate receptors. They exhibit pharmacological…”
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1-Benzazepine derivatives acting as ATP-dependent potassium-channels antagonists by Corbel, JC, Uriac, P, Huet, J, Martin, CAE, Advenier, C

“…In order to select between various pharmacological activities related to the 1-benzazepine nucleus, a set of 1-benzazepine derivatives bearing different N-1 or…”
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Synthesis of heterocyclic enamine-zinc complexes as precursors of stereocontrolled substitution of nitrogen α-position by Tran, Hoang-Van, Vu, Huy-Dinh, Graton, Jérôme, Jacquemin, Denis, Renault, Jacques, Uriac, Philippe

“…[Display omitted] •Enamine-zinc complexes.•Stereoselective addition on cyclic iminiums.•2-Substituted nitrogen heterocycles.•(rac)-Homoconiine and coniine…”
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Solid phase synthesis of sulphonamides: novel ligands of 5-HT6 receptors by Renault, J., Fabis, F., Dauphin, F., Lebranchu, M., Roch, M. Le, Butt, S., Uriac, P., Rault, S.

“…Using solid phase synthesis techniques, we have rapidly obtained a series of eight aryl sulphonamides derived from putrescine. These conjugates with various…”
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Oxidation of 2,3- and 2,5-dihydro-1H-1-benzazepines by hydride transfer to an iminium ion: Synthesis of 3H-1-benzazepines by Kharraz, B., Uriac, P., Sinbandhit, S., Toupet, L.

“…Mechanism: Hydride transfer from 1 or 2 to the iminium ion 3′f giving 6f and 5. In the case of 2, compound 5 is directly obtained. Some 3H-1-benzazepines were…”
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Inhibition of tumor growth and polyamine uptake by tetracyclic amidines bearing a putrescine moiety by Mens, T, Tomasi, S, Eifler-Lima, V L, Uriac, P, Huet, J, Catros-Quemener, V

“…Tetracyclic amidines (tetrahydroquino[4.3-b][l]benzazepine: compound 11 and tetrahydrobenzo[k]naphthyridine: compound 12) bearing a putrescine moiety possess…”
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Stictic Acid Derivatives from the Lichen Usnea articulata and Their Antioxidant Activities by Lohézic-Le Dévéhat, Françoise, Tomasi, Sophie, Elix, John A, Bernard, Aurélie, Rouaud, Isabelle, Uriac, Philippe, Boustie, Joël

“…Two new β-orcinol depsidones, 1 and 2, together with 13 known compounds were isolated from the lichen Usnea articulata. The structures of 1 and 2 were…”
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Electrochemical oxidation of 2,5-dihydro- 1h-1-benzazepines : Synthesis of 5H-1-benzazepines by Kharraz, B., Uriac, P., Toupet, L., Hurvois, J.P., Moinet, C., Tallec, A.

“…Formation of 5H-1-benzazepines was observed after electrochemical oxidation of the title compounds in a flow cell at a graphite felt anode and in acetic…”
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Effect of Spermine Conjugation on the Cytotoxicity and Cellular Transport of Acridine by Delcros, Jean-Guy, Tomasi, Sophie, Carrington, Simon, Martin, Bénédicte, Renault, Jacques, Blagbrough, Ian S, Uriac, Philippe

“…Polyamines are believed to be potent vectors for the selective delivery of chemotherapeutic agents into cancer cells. In this paper, we report the effect of…”
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Effect of Polyamine Homologation on the Transport and Biological Properties of Heterocyclic Amidines by Delcros, Jean-Guy, Tomasi, Sophie, Duhieu, Stéphane, Foucault, Marine, Martin, Bénédicte, Le Roch, Myriam, Eifler-Lima, Vera, Renault, Jacques, Uriac, Philippe

“…Five sets of heterocyclic derivatives of various sizes and complexities coupled by an amidine function to putrescine, spermidine, or spermine were prepared…”
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Synthesis of a Laterally Branched Polyamine from α-Methylene-γ-butyrolactone by Jean, Mickaël, Le Roch, Myriam, Renault, Jacques, Uriac, Philippe

“…A polyamine derivative was prepared from α-methylene-γ-butyrolactone. This method used Michael addition and lactone aminolysis followed by the nucleophilic…”
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Parallel Supported Synthesis of Polyamine−Imidazole Conjugates by Picard, Sylvie, Le Roch, Myriam, Renault, Jacques, Uriac, Philippe

“…A small collection of nine polyamine−imidazole conjugates, potentially acting as RNases A mimics, has been synthesized on SynPhase lanterns using amino…”
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Solid-phase combinatorial synthesis of polyamine derivatives using aminoalcohol building blocks by Renault, Jacques, Lebranchu, Marina, Lecat, Anne, Uriac, Philippe

“…A systematic study of nucleophilic displacement of mesyl groups using benzylamine was carried out on Multipin Synphase™ supports. The optimal conditions were…”
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Antibacterial activity of glycine betaine analogues: involvement of osmoporters by COSQUER, Anne, FICAMOS, Morgane, JEBBAR, Mohamed, CORBEL, Jean-Charles, CHOQUET, Gwénaëlle, FONTENELLE, Catherine, URIAC, Philippe, BERNARD, Théophile

“…Glycine betaine (GB) analogues were obtained using solid phase organic synthesis and assayed for their toxic activity against 15 Gram positive and Gram…”
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Synthesis of dihydroxylated polyamines from an erythronolactone by Le Roch, Myriam, Renault, Jacques, Penlaë, Kristell, Uriac, Philippe

“…The opening of protected erythronolactone by an amine or a diamine furnished hydroxy-amides. Their multistep functional conversion led to either selectively…”
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Synthesis of New Quinoxaline Derivatives by Reductive Cyclization of Various 1-(2-Nitrophenyl)-2-cyanoamines by Renaud, Tristan, Hurvois, Jean-Pierre, Uriac, Philippe

“…The electrochemical cyanation of various six‐membered N‐(2‐nitrophenyl) heterocyclic amines, including piperidine, morpholine, thiomorpholine, and…”
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Pharmacomodulation of a sulfamide 5-HT6 receptor ligand by Renault, Jacques, Bernard, Aurelie, Brajeul, Solenn, Verhaeghe, Pierre, Butt, Sabrina, Fabis, Frederic, Dauphin, François, Uriac, Philippe, Rault, Sylvain

“…A series of N-omega-aminoalkyl- or N-omega-amidinoalkyl-2,4,6-triisopropyl benzenesulfonamides has been synthesized and their respective affinity indices on…”
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Solid phase organic synthesis of polyamine derivatives and initial biological evaluation of their antitumoral activity by Tomasi, Sophie, Le Roch, Myriam, Renault, Jacques, Corbel, Jean-Charles, Uriac, Philippe, Carboni, Bertrand, Moncoq, Damien, Martin, Bénedicte, Delcros, Jean-Guy

“…A series of N 1-monosubstituted putrescine and spermine derivatives was synthesised using a solid phase methodology. We evaluated their cytotoxicity,…”
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Toxicity and osmoprotective activities of analogues of glycine betaine obtained by solid phase organic synthesis towards Sinorhizobium meliloti by Cosquer, Anne, Pichereau, Vianney, Le Mée, Didier, Le Roch, Myriam, Renault, Jacques, Carboni, Bertrand, Uriac, Philippe, Bernard, Théophile

“…Seven analogues of the bacterial osmoprotectant glycine betaine (GB, trimethylammonioacetate), in which the methyl groups of the Me 3N + moiety are replaced by…”
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