Search Results - "Urbano‐Ispízua, Alvaro"

Allogeneic peripheral blood stem cell transplantation with reduced‐intensity conditioning: results of a prospective multicentre study by Martino, Rodrigo, Caballero, María Dolores, Canals, Carmen, Simón, José Antonio Pérez, Solano, Carlos, Urbano‐Ispízua, Alvaro, Bargay, Joan, Rayón, Consolación, Léon, Antonio, Sarrá, Josep, Odriozola, Jesús, Conde, Javier García, Sierra, Jorge, San Miguel, Jesús

“…Reduced‐intensity conditioning (RIC) regimens for allogeneic haematopoietic stem cell transplantation (SCT) have been shown to lead to engraftment of donor…”
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The academic point-of-care anti-CD19 chimeric antigen receptor T-cell product varnimcabtagene autoleucel (ARI-0001 cells) shows efficacy and safety in the treatment of relapsed/refractory B-cell non-Hodgkin lymphoma by Martínez-Cibrián, Núria, Ortiz-Maldonado, Valentín, Español-Rego, Marta, Blázquez, Andrea, Cid, Joan, Lozano, Miquel, Magnano, Laura, Giné, Eva, Correa, Juan G, Mozas, Pablo, Rodríguez-Lobato, Luis Gerardo, Rivero, Andrea, Montoro-Lorite, Mercedes, Ayora, Pilar, Navarro, Sergio, Alserawan, Leticia, González-Navarro, E Azucena, Castellà, Maria, Sánchez-Castañón, María, Cabezón, Raquel, Benítez-Ribas, Daniel, Setoaín, Xavier, Rodríguez, Sonia, Brillembourg, Helena, Varea, Sara, Olesti, Eulalia, Guillén, Elena, Sáez-Peñataro, Joaquín, de Larrea, Carlos Fernández, López-Guillermo, Armando, Pascal, Mariona, Urbano-Ispizua, Álvaro, Juan, Manel, Delgado, Julio

“…Varnimcabtagene autoleucel (var-cel) is an academic anti-CD19 chimeric antigen receptor (CAR) product used for the treatment of non-Hodgkin lymphoma (NHL) in…”
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Serum mass spectrometry for treatment monitoring in patients with multiple myeloma receiving ARI0002h CAR T-cells by Ortiz de Landazuri, Iñaki, Oliver-Caldés, Aina, Español-Rego, Marta, Agulló, Cristina, Contreras, María Teresa, Zabaleta, Aintzane, Puig, Noemí, Cabañas, Valentín, González-Calle, Verónica, Zugasti, Inés, Inogés, Susana, Rodríguez Otero, Paula, Martin-Antonio, Beatriz, Reguera, Juan Luis, López-Diaz de Cerio, Ascensión, Aróstegui, Juan Ignacio, Uribe-Herranz, Mireia, Benítez-Ribas, Daniel, Rodríguez-Lobato, Luis Gerardo, González, Europa Azucena, Tovar, Natalia, Charry, Paola, Navarro, Sergio, Rosiñol, Laura, Tréboles, Karen, Mora, Génesis, Yagüe, Jordi, Moraleda, José María, Urbano-Ispizua, Álvaro, Mateos, María Victoria, Pascal, Mariona, Paiva, Bruno, Juan, Manel, Fernández de Larrea, Carlos

“…Chimeric antigen receptor (CAR) T-cell therapies have increased the patients with relapsed/refractory multiple myeloma (RRMM) in whom standard electrophoretic…”
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Evaluation of European LeukemiaNet 2022 risk classification in patients undergoing allogeneic haematopoietic stem cell transplantation for acute myeloid leukaemia: Identification of a very poor prognosis genetic group by Jiménez‐Vicente, Carlos, Charry, Paola, Castaño‐Diez, Sandra, Guijarro, Francesca, López‐Guerra, Mònica, Pérez‐Valencia, Amanda Isabel, Martinez‐Roca, Alexandra, Cortés‐Bullich, Albert, Munárriz, Daniel, Solano, Maria Teresa, Rosiñol, Laura, Carreras, Enric, Urbano‐Ispizua, Álvaro, Fernández‐Avilés, Francesc, Martinez, Carmen, Suárez‐Lledó, María, Díaz‐Beyá, Marina, Rovira, Montserrat, Salas, María Queralt, Esteve, Jordi

“…Summary European LeukemiaNet refined their risk classification of acute myeloid leukaemia (AML) in 2022 (ELN 2022) according to the two new myeloid…”
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Evaluation of cell collection efficiency in non‐mobilized adult donors for autologous chimeric antigen receptor T‐cell manufacturing by Piñeyroa, Juan A., Cid, Joan, Vlagea, Alexandru, Carbassé, Gloria, Henao, Paola, Bailo, Noemí, Ortiz‐Maldonado, Valentín, Martínez‐Cibrian, Núria, Español, Marta, Delgado, Julio, Urbano‐Ispizua, Álvaro, Lozano, Miquel

“…Background and Objectives Data about collection efficiency 1 (CE1), which takes into account blood cell counts before and after collection, thus providing a…”
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Baseline characteristics and disease burden in patients in the International Paroxysmal Nocturnal Hemoglobinuria Registry by Schrezenmeier, Hubert, Muus, Petra, Socié, Gérard, Szer, Jeffrey, Urbano-Ispizua, Alvaro, Maciejewski, Jaroslaw P, Brodsky, Robert A, Bessler, Monica, Kanakura, Yuzuru, Rosse, Wendell, Khursigara, Gus, Bedrosian, Camille, Hillmen, Peter

“…Paroxysmal nocturnal hemoglobinuria is a rare, acquired disease associated with hemolytic anemia, bone marrow failure, thrombosis, and, frequently, poor…”
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Infection epidemiology in relation to different therapy phases in patients with haematological malignancies receiving CAR T‐cell therapy by Garcia‐Pouton, Nicol, Ortiz‐Maldonado, Valentín, Peyrony, Oliver, Chumbita, Mariana, Aiello, Tommaso Francesco, Monzo‐Gallo, Patricia, Lopera, Carlos, Puerta‐Alcalde, Pedro, Magnano, Laura, Martinez‐Cibrian, Nuria, Pitart, Cristina, Juan, Manel, Delgado, Julio, Fernandez De Larrea, Carlos, Soriano, Álex, Urbano‐Ispizua, Álvaro, Garcia‐Vidal, Carolina

“…Background We described the real‐life epidemiology and causes of infections on the different therapy phases in patients undergoing chimeric antigen receptor…”
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Efficacy and safety of one‐day offline extracorporeal photopheresis schedule processing one total blood volume for treating patients with graft‐versus‐host disease by Cid, Joan, Carbassé, Gloria, Suárez‐Lledó, María, Moreno, David F., Martínez, Carmen, Gutiérrez‐García, Gonzalo, Fernández‐Avilés, Francesc, Rosiñol, Laura, Giavedoni, Priscila, Mascaró, José M., Agustí, Carles, Marín, Pedro, Rovira, Montserrat, Urbano‐Ispizua, Álvaro, Lozano, Miquel

“…BACKGROUND Extracorporeal photopheresis (ECP) has been increasingly used as a second‐line therapy for graft‐versus‐host disease (GVHD) but there is no…”
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Autologous transplantation versus allogeneic transplantation in patients with follicular lymphoma experiencing early treatment failure by Smith, Sonali M., Godfrey, James, Ahn, Kwang Woo, DiGilio, Alyssa, Ahmed, Sairah, Agrawal, Vaibhav, Bachanova, Veronika, Bacher, Ulrike, Bashey, Asad, Bolaños‐Meade, Javier, Cairo, Mitchell, Chen, Andy, Chhabra, Saurabh, Copelan, Edward, Dahi, Parastoo B., Aljurf, Mahmoud, Farooq, Umar, Ganguly, Siddhartha, Hertzberg, Mark, Holmberg, Leona, Inwards, David, Kanate, Abraham S., Karmali, Reem, Kenkre, Vaishalee P., Kharfan‐Dabaja, Mohamed A., Klein, Andreas, Lazarus, Hillard M., Mei, Matthew, Mussetti, Alberto, Nishihori, Taiga, Ramakrishnan Geethakumari, Praveen, Saad, Ayman, Savani, Bipin N., Schouten, Harry C., Shah, Nirav, Urbano‐Ispizua, Alvaro, Vij, Ravi, Vose, Julie, Sureda, Anna, Hamadani, Mehdi

“…BACKGROUND Early treatment failure (ETF) in follicular lymphoma (FL), defined as relapse or progression within 2 years of frontline chemoimmunotherapy, is a…”
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Results of ARI‐0001 CART19 cell therapy in patients with relapsed/refractory CD19‐positive acute lymphoblastic leukemia with isolated extramedullary disease by Ortiz‐Maldonado, Valentín, Alonso‐Saladrigues, Anna, Español‐Rego, Marta, Martínez‐Cibrián, Nuria, Faura, Anna, Magnano, Laura, Català, Albert, Benítez‐Ribas, Daniel, Giné, Eva, Díaz‐Beyá, Marina, Correa, Juan Gonzalo, Rovira, Montserrat, Montoro‐Lorite, Mercedes, Martínez‐Roca, Alexandra, Rodríguez‐Lobato, Luis Gerardo, Cabezón, Raquel, Cid, Joan, Lozano, Miquel, Garcia‐Rey, Enric, Conde, Nuria, Pedrals, Georgina, Rozman, María, Torrebadell, Montserrat, Setoain, Xavier, Rodríguez, Sonia, Esteve, Jordi, Pascal, Mariona, Urbano‐Ispizua, Álvaro, Juan, Manel, Delgado, Julio, Rives, Susana

“…We evaluated outcomes of 18 patients with isolated extramedullary disease (iEMD) relapsed/refractory (R/R) B‐cell acute lymphoblastic leukemia (B‐ALL) treated…”
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Increased collection efficiency of CD34+ cells after mobilization with preemptive use of plerixafor followed by leukocytapheresis on the same day by Cid, Joan, Castillo, Carlos, Marín, Pedro, Carbassé, Gloria, Herrera, Dolores, Monfort, Nuria, Fernández‐Avilés, Francesc, Gutiérrez‐García, Gonzalo, Martínez, Carmen, Rosiñol, Laura, Suárez‐Lledó, María, Rovira, Montserrat, Urbano‐Ispizua, Álvaro, Lozano, Miquel

“…BACKGROUND Plerixafor should be administered 6 to 11 hours before starting leukocytapheresis. However, we have been using plerixafor followed by…”
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Results of a phase 1/2 study of cemdisiran in healthy subjects and patients with paroxysmal nocturnal hemoglobinuria by Gaya, Anna, Munir, Talha, Urbano‐Ispizua, Alvaro, Griffin, Morag, Taubel, Jorg, Bush, Jim, Bhan, Ishir, Borodovsky, Anna, Wang, Yue, Badri, Prajakta, Garg, Pushkal

“…Complement dysregulation underpins the physiopathology of paroxysmal nocturnal hemoglobinuria (PNH). Cemdisiran, an RNA interference investigational treatment,…”
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Mitochondria underlie different metabolism of hematopoietic stem and progenitor cells by Arranz, Lorena, Urbano-Ispizúa, Alvaro, Méndez-Ferrer, Simón

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Impact of Early Intrapatient Variability of Tacrolimus Concentrations on the Risk of Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation Using High-Dose Post-Transplant Cyclophosphamide by Marco, Daniel N, Salas, María Queralt, Gutiérrez-García, Gonzalo, Monge, Inés, Riu, Gisela, Carcelero, Esther, Roma, Joan Ramón, Llobet, Noemí, Arcarons, Jordi, Suárez-Lledó, María, Martínez, Nuria, Pedraza, Alexandra, Domenech, Ariadna, Rosiñol, Laura, Fernández-Avilés, Francesc, Urbano-Ispízua, Álvaro, Rovira, Montserrat, Brunet, Mercè, Martínez, Carmen

“…Tacrolimus (Tac) is a pivotal immunosuppressant agent used to prevent graft-versus-host disease (GVHD) after allogeneic stem cell transplantation (alloHSCT)…”
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Graft-versus-host disease therapy: something else beyond glucocorticoids? by Martínez, Carmen, Urbano-Ispízua, Alvaro

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The Genotype of the Donor for the (GT)n Polymorphism in the Promoter/Enhancer of FOXP3 Is Associated with the Development of Severe Acute GVHD but Does Not Affect the GVL Effect after Myeloablative HLA-Identical Allogeneic Stem Cell Transplantation by Noriega, Víctor, Martínez-Laperche, Carolina, Buces, Elena, Pion, Marjorie, Sánchez-Hernández, Noemí, Martín-Antonio, Beatriz, Guillem, Vicent, Bosch-Vizcaya, Anna, Bento, Leyre, González-Rivera, Milagros, Balsalobre, Pascual, Kwon, Mi, Serrano, David, Gayoso, Jorge, de la Cámara, Rafael, Brunet, Salut, Rojas-Contreras, Rafael, Nieto, José B, Martínez, Carmen, Gónzalez, Marcos, Espigado, Ildefonso, Vallejo, Juan C, Sampol, Antonia, Jiménez-Velasco, Antonio, Urbano-Ispizua, Alvaro, Solano, Carlos, Gallardo, David, Díez-Martín, José L, Buño, Ismael

“…The FOXP3 gene encodes for a protein (Foxp3) involved in the development and functional activity of regulatory T cells (CD4+/CD25+/Foxp3+), which exert…”
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Pharmacodynamics of T cell function for monitoring pharmacologic immunosuppression after allogeneic hematopoietic stem cell transplantation by Martínez, Carmen, Millán, Olga, Rovira, Montserrat, Fernández-Avilés, Francesc, López, Anna, Suárez-Lledó, María, Carreras, Enric, Urbano-Ispízua, Álvaro, Brunet, Mercè

“…Information on pharmacodynamic monitoring after allogeneic hematopoietic cell transplantation (allo-SCT) to evaluate individual responses to immunosuppressive…”
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The hospital exemption pathway for the approval of advanced therapy medicinal products: an underused opportunity? The case of the CAR-T ARI-0001 by Trias, Esteve, Juan, Manel, Urbano-Ispizua, Alvaro, Calvo, Gonzalo

“…In February 2021, the ‘Advanced Therapy Medicinal Product’ (ATMP) ARI-0001 (CART19-BE-01), developed at Hospital Clínic de Barcelona (Spain), received…”
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CAR-T Cell Therapy: A Door Is Open to Find Innumerable Possibilities of Treatments for Cancer Patients by Perez-Amill, Lorena, Marzal, Berta, Urbano-Ispizua, Alvaro, Juan, Manel, Martín-Antonio, Beatriz

“…Seven years ago a chronic lymphocytic leukemia patient was for the first time successfully treated with chimeric antigen receptor (CAR)-modified T cells (CAR-T…”
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CTLA-4 polymorphisms and clinical outcome after allogeneic stem cell transplantation from HLA-identical sibling donors by Pérez-García, Arianne, De la Cámara, Rafael, Román-Gómez, Jose, Jiménez-Velasco, Antonio, Encuentra, Maite, Nieto, Jose B., de la Rubia, Javier, Urbano-Ispizúa, Alvaro, Brunet, Salut, Iriondo, Arturo, González, Marcos, Serrano, David, Espigado, Ildefonso, Solano, Carlos, Ribera, Josep M., Pujal, Josep M., Hoyos, Montserrat, Gallardo, David

“…CTLA-4 is an inhibitory molecule that down-regulates T-cell activation. Although polymorphisms at CTLA-4 have been correlated with autoimmune diseases their…”
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