Search Results - "Urban, Robert G"

Unexpected Association between Induction of Immunity to the Universal Tumor Antigen CYP1B1 and Response to Next Therapy by GRIBBEN, John G, RYAN, David P, RICHARDSON, Paul G, MARSHALL, Blossom, NEUBERG, Donna, NADLER, Lee M, BOYAJIAN, Richard, URBAN, Robert G, HEDLEY, Mary L, BEACH, Kathleen, NEALON, Patrick, MATULONIS, Ursula, CAMPOS, Susana, GILLIGAN, Timothy D

“…Purpose: The carcinogen activator cytochrome P450 1B1 (CYP1B1) is expressed on almost all human tumors with rare expression on normal tissues…”
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Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 by Brown, Jerry H, Jardetzky, Theodore S, Gorga, Joan C, Stern, Lawrence J, Urban, Robert G, Strominger, Jack L, Wiley, Don C

“…The three-dimensional structure of the class II histocompatibility glycoprotein HLA-DR1 from human B-cell membranes has been determined by X-ray…”
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Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size by Chicz, Roman M, Urban, Robert G, Lane, William S, Gorga, Joan C, Stern, Lawrence J, Vignali, Dario A. A, Strominger, Jack L

“…Peptides bound to class I molecules are 8-10 amino acids long, and possess a binding motif representative of peptides that bind to a given class I allele. In…”
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Dynamics of Human Papillomavirus Infection between Biopsy and Excision of Cervical Intraepithelial Neoplasia: Results from the ZYC101a Protocol by Crum, Christopher P., Beach, Kathleen J., Hedley, Mary L., Yuan, Liping, Lee, Kenneth R., Wright, Thomas C., Urban, Robert G.

“…Background. Little is known about the dynamics of human papillomavirus (HPV) during the follow-up of cervical intraepithelial neoplasia (CIN) 2/3 after biopsy…”
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Pillars Article: Three-Dimensional Structure of a Human Class II Histocompatibility Molecule Complexed with Superantigen. Nature . 1994. 368: 711-718 by Jardetzky, Theodore S, Brown, Jerry H, Gorga, Joan C, Stern, Lawrence J, Urban, Robert G, Chi, Young-In, Stauffacher, Cynthia, Strominger, Jack L, Wiley, Don C

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ZYC101a for Treatment of High-Grade Cervical Intraepithelial Neoplasia: A Randomized Controlled Trial by Garcia, Francisco, Petry, Karl Ulrich, Muderspach, Laila, Gold, Michael A, Braly, Patricia, Crum, Christopher P, Magill, Marianne, Silverman, Michael, Urban, Robert G, Hedley, Mary Lynne, Beach, Kathleen J

“…OBJECTIVE:The objective of this study was to assess the safety and efficacy of a novel therapeutic, ZYC101a, for the treatment of women with histologically…”
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Immunization with a poly (lactide co-glycolide) encapsulated plasmid DNA expressing antigenic regions of HPV 16 and 18 results in an increase in the precursor frequency of T cells that respond to epitopes from HPV 16, 18, 6 and 11 by Matijevic, Mark, Hedley, Mary Lynne, Urban, Robert G., Chicz, Roman M., Lajoie, Christa, Luby, Thomas M.

“…► Immunization with amolimogene induces T cells specific to HPV in HSIL subjects. ► Amolimogene expresses T cell epitopes from E6/E7 proteins of HPV types 16…”
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Encapsulated plasmid DNA treatment for human papillomavirus 16-associated anal dysplasia: A Phase I study of ZYC101 by KLENCKE, Barbara, MATIJEVIC, Mark, JAY, Naomi, DA COSTA, Maria, PALEFSKY, Joel M, URBAN, Robert G, LATHEY, Janet L, HEDLEY, Mary Lynne, BERRY, Michael, THATCHER, Joe, WEINBERG, Vivian, WILSON, Jennifer, DARRAGH, Teresa

“…High-grade dysplasia induced by high-risk types of human papillomavirus (HPV) precedes invasive cancer in anal squamous epithelium just as it does in the…”
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Immunotherapy of human cervical high-grade cervical intraepithelial neoplasia with microparticle-delivered human papillomavirus 16 E7 plasmid DNA by Sheets, Ellen E., Urban, Robert G., Crum, Christopher P., Hedley, Mary Lynne, Politch, Joseph A., Gold, Michael A., Muderspach, Laila I., Cole, Geoffrey A., Crowley-Nowick, Peggy A.

“…Objective: The purpose of this study was to evaluate the safety of the administration of a bacterial expression plasmid encoding a 13 amino acid sequence that…”
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Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide by Stern, Lawrence J, Brown, Jerry H, Jardetzky, Theodore S, Gorga, Joan C, Urban, Robert G, Strominger, Jack L, Wiley, Don C

“…An influenza virus peptide binds to HLA-DR1 in an extended conformation with a pronounced twist. Thirty-five per cent of the peptide surface is accessible to…”
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Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen by Jardetzky, Theodore S, Brown, Jerry H, Gorga, Joan C, Stern, Lawrence J, Urban, Robert G, Chi, Young-in, Stauffacher, Cynthia, Strominger, Jack L, Wiley, Don C

“…The structure of a bacterial superantigen, Staphylococcus aureus enterotoxin B, bound to a human class II histocompatibility complex molecule (HLA-DR1) has…”
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Use of interferon-gamma ELISPOT in monitoring immune responses in humans by Matijevic, Mark, Urban, Robert G

“…The interferon (IFN)-gamma enzyme-linked immunospot (ELISPOT) assay has become a useful tool for immunologists seeking to quantify immune responses on a…”
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Toxic Shock Syndrome Toxin-1 Complexed with a Class II Major Histocompatibility Molecule HLA-DR1 by Kim, Jongsun, Urban, Robert G., Strominger, Jack L., Wiley, Don C.

“…The three-dimensional structure of a Staphylococcus aureus superantigen, toxic shock syndrome toxin-1 (TSST-1), complexed with a human class II major…”
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A Subset of HLA-B27 Molecules Contains Peptides Much Longer than nonamers by Urban, Robert G., Chicz, Roman M., Lane, William S., Strominger, Jack L., Rehm, Armin, Marcel J. H. Kenter, Fons G. C. M. Uytdehaag, Ploegh, Hidde, Uchanska-Ziegler, Barbara, Ziegler, Andreas

“…An unusual monoclonal antibody (MARB4) directed against HLA-B27 that reacts with only ≈5-20% of the cell surface HLA-B27 was used for large-scale purification…”
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Pillars article: three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 1993. 364: 33-39 by Brown, Jerry H, Jardetzky, Theodore S, Gorga, Joan C, Stern, Lawrence J, Urban, Robert G, Strominger, Jack L, Wiley, Don C

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Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles by CHICZ, R. M, URBAN, R. G, GORGA, J. C, VIGNALI, D. A. A, LANE, W. S, STROMINGER, J. L

“…Naturally processed peptides were acid extracted from immunoaffinity-purified HLA-DR2, DR3, DR4, DR7, and DR8. Using the complementary techniques of mass…”
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Crystallographic Analysis of Endogenous Peptides Associated with HLA-DR1 Suggests a Common, Polyproline II-Like Conformation for Bound Peptides by Jardetzky, Theodore S., Brown, Jerry H., Gorga, Joan C., Stern, Lawrence J., Urban, Robert G., Strominger, Jack L., Wiley, Don C.

“…The structure of the human major histocompatibility complex (MHC) class II molecule HLA-DR1 derived from the human lymphoblastoid cell line LG-2 has been…”
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Staphylococcal enterotoxin A has two cooperative binding sites on major histocompatibility complex class II by Hudson, K R, Tiedemann, R E, Urban, R G, Lowe, S C, Strominger, J L, Fraser, J D

“…The superantigen staphylococcal enterotoxin A (SEA) binds to major histocompatibility complex (MHC) class II molecules at two sites on either side of the…”
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Macaques immunized with HLA-DR are protected from challenge with simian immunodeficiency virus by Arthur, L O, Bess, Jr, J W, Urban, R G, Strominger, J L, Morton, W R, Mann, D L, Henderson, L E, Benveniste, R E

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Encapsulated Plasmid DNA Treatment for Human Papillomavirus 16-associated Anal Dysplasia by Barbara Klencke, Mark Matijevic, Robert G. Urban, Janet L. Lathey, Mary Lynne Hedley, Michael Berry, Joe Thatcher, Vivian Weinberg, Jennifer Wilson, Teresa Darragh, Naomi Jay, Maria Da Costa, Joel M. Palefsky

“…High-grade dysplasia induced by high-risk types of human papillomavirus (HPV) precedes invasive cancer in anal squamous epithelium just as it does in the…”
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