Search Results - "Urban, J.F. Jr"

Infection with parasitic nematodes confounds vaccination efficacy by Urban, Joseph F., Steenhard, Nina R., Solano-Aguilar, Gloria I., Dawson, Harry D., Iweala, Onyinye I., Nagler, Cathryn R., Noland, Gregory S., Kumar, Nirbhay, Anthony, Robert M., Shea-Donohue, Terez, Weinstock, Joel, Gause, William C.

“…T helper (Th) cells produce signature cytokine patterns, induced largely by intracellular versus extracellular pathogens that provide the cellular and…”
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Cytokine regulation of host defense against parasitic gastrointestinal nematodes: Lessons from Studies with Rodent Models by Finkelman, F.D, Shea-Donohue, T, Goldhill, J, Sullivan, C.A, Morris, S.C, Madden, K.B, Gause, W.C, Urban, J.F. Jr

“…Studies with rodents infected with Trichinella spiralis, Heligmosomoides polygyrus, Nippostrongylus brasiliensis, and Trichuris muris have provided…”
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interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice by Noben-Trauth, N, Shultz, L.D, Brombacher, F, Urban, J.F. Jr, Gu, H, Paul, W.E

“…IL-4 receptor alpha chain (IL-4R alpha)-deficient mice were generated by gene-targeting in BALB/c embryonic stem cells. Mutant mice showed a loss of IL-4…”
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Peripheral CD4 T Cells Rapidly Accumulate at the Host:Parasite Interface during an Inflammatory Th2 Memory Response by Morimoto, Motoko, Morimoto, Masahiro, Whitmire, Jeannette, Xiao, Shiyun, Anthony, Robert M, Mirakami, Hiroshi, Star, Robert A, Urban, Joseph F., Jr, Gause, William C

“…Memory peripheral Th2 immune responses to infectious pathogens are not well studied due to the lack of suitable models and the difficulty of assessing Th2…”
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Survival of North American genotypes of Trichinella in frozen pork by Hill, D E, Forbes, L, Zarlenga, D S, Urban, Jr, J F, Gajadhar, A A, Gamble, H R

“…North American genotypes of Trichinella spiralis (T-1), Trichinella nativa (T-2), Trichinella pseudospiralis (T-4), Trichinella murrelli (T-5), and Trichinella…”
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CpG-oligodeoxynucleotides enhance porcine immunity to Toxoplasma gondii by Kringel, H, Dubey, J.P, Beshah, E, Hecker, R, Urban, J.F

“…Protection against a challenge infection with Toxoplasma gondii VEG strain oocysts was examined in pigs after vaccination with T. gondii RH strain tachyzoites…”
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Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice by Urban, J.F. Jr. (Helminthic Diseases Laboratory, ARS, USDA, Beltsville, MD), Katona, I.M, Paul, W.E, Finkelman, F.D

“…Parasitic helminths typically induce components of immediate-type hypersensitivity, including elevated serum IgE, eosinophilia, and mucosal mast cells. These…”
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The pathogenesis of necrotic proliferative colitis in swine is linked to whipworm induced suppression of mucosal immunity to resident bacteria by Mansfield, L.S., Urban, J.F.

“…Mucohemorrhagic enteritis syndrome in swine has a complex etiology with largely unknown pathogenesis. We have observed that inoculation of pigs with swine…”
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Effect of protease class-specific inhibitors on in vitro development of the third- to fourth-stage larvae of Ascaris suum by Rhoads, M.L. (Parasite Biology and Epidemiology Laboratory, USDA, ARS, Beltsville, MD.), Fetterer, R.H, Urban, J.F. Jr

“…Third-stage larvae (L3) of Ascaris suum develop and molt to fourth-stage larvae (L4) during in vitro cultivation; consistently greater than 80% of the larvae…”
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Secretion of an aminopeptidase during transition of third- to fourth-stage larvae of Ascaris suum by Rhoads, L, Fetterer, R.H, Urban, J.F. Jr

“…Protease activity was identified in culture fluids collected during in vitro development of L3 to L4 larval stages of Ascaris suum. Fluorogenic peptide…”
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Local TH1 and TH2 responses to parasitic infection in the intestine: regulation by IFN-gamma and IL-4 by Urban, J.F., Fayer, R., Sullivan, C., Goldhill, J., Shea-Donohue, T., Madden, K., Morris, S.C., Katona, I., Gause, W., Ruff, M., Mansfield, L.S., Finkelman, F.D.

“…Control of parasitic infections is dependent on the production of cytokines that activate mechanisms which limit invasion, reproduction or survival of the…”
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Heligmosomoides polygyrus: CD4+ but not CD8+ T cells regulate the IgE response and protective immunity in mice by Urban, Jr, J F, Katona, I M, Finkelman, F D

“…Oral inoculation of BALB/c mice with infective larvae of Heligmosomoides polygyrus resulted in chronic infection characterized by the release of parasite eggs…”
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Persistence of immunity to toxoplasmosis in pigs vaccinated with a nonpersistent strain of Toxoplasma gondii by Dubey, J P, Baker, D G, Davis, S W, Urban, Jr, J F, Shen, S K

“…Persistence of the vaccine RH strain of Toxoplasma gondii was studied by bioassay and histologically in 14 pigs. Pigs were euthanatized 2, 4, 7, 8, 14, 15, 21,…”
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A Trichuris specific diagnostic antigen from culture fluids of Trichuris suis adult worms by Hill, Dolores E., Romanowski, Robert D., Urban, Joseph F.

“…Trichuris suis is a nematode parasite of swine which can cause serious pathology in infected pigs, such as anorexia, diarrhea, anemia, and death in heavy…”
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The pathogenesis of necrotic profilerative colitis in swine is linked to whipworm induced suppression of mucosal immunity to resident bacteria by Mansfield, L.S. (Michigan State Univ., East Lansing, MI (USA). Coll. of Veterinary Medicine), Urban, J.F. Jr

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Trichuris suis: a zinc metalloprotease from culture fluids of adult parasites by Hill, D E, Gamble, H R, Rhoads, M L, Fetterer, R H, Urban, Jr, J F

“…A zinc metalloendoprotease has been isolated from in vitro culture fluids of Trichuris suis adults. The protease was purified from total culture fluids by…”
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Protective immunity to toxoplasmosis in pigs vaccinated with a nonpersistent strain of Toxoplasma gondii by Dubey, J P, Urban, Jr, J F, Davis, S W

“…The RH strain of Toxoplasma gondii is highly virulent; 1 infective organism is uniformly lethal for mice. Three pigs inoculated SC with 10(3) tachyzoites of…”
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The effect of immunization of pigs with Ascaris suum cuticle components on the development of resistance to parenteral migration during a challenge infection by Hill, D E, Fetterer, R H, Romanowski, R D, Urban, Jr, J F

“…The development of immunity to Ascaris suum was studied in pigs immunized with isolated cuticle fragments from A. suum second and third stage larvae (L2/L3)…”
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Ascaris suum: development of intestinal immunity to infective second-stage larvae in swine by Urban, Jr, J F, Alizadeh, H, Romanowski, R D

“…The development of protective immunity to Ascaris suum was examined in pigs naturally exposed to eggs on a contaminated dirt lot. Pigs became almost totally…”
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Diagnosis of transplacentally induced toxoplasmosis in pigs by Dubey, J P, Urban, Jr, J F

“…Seventeen sows were fed 1,000 Toxoplasma gondii oocysts of isolates GT-1 or PT-1 at 32 to 92 days of gestation, and the products of conception were examined…”
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