Search Results - "Urban, Alan"
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Real-time imaging of brain activity in freely moving rats using functional ultrasound
Published in Nature methods (01-09-2015)“…A miniaturized ultrasound probe enables functional brain imaging in freely behaving rats. The large field of view and deep penetration makes this technique…”
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Functional ultrasound imaging of stroke in awake rats
Published in eLife (21-11-2023)“…Anesthesia is a major confounding factor in preclinical stroke research as stroke rarely occurs in sedated patients. Moreover, anesthesia affects both brain…”
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Quantitative Hemodynamic Measurements in Cortical Vessels Using Functional Ultrasound Imaging
Published in Frontiers in neuroscience (12-04-2022)“…Red blood cell velocity (RBCv), cerebral blood flow (CBF), and volume (CBV) are three key parameters when describing brain hemodynamics. Functional ultrasound…”
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Impact of biocontrol agents on Lantana camara in an inland area of South Africa
Published in BioControl (Dordrecht, Netherlands) (01-04-2020)“…Lantana camara L. (Verbenaceae) is a weed of significant concern in many tropical and subtropical countries. This work aimed to quantify the combined impact of…”
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SINGLE VOXEL CLUSTERING AS A VERSATILE TOOL FOR FUNCTIONAL ULTRASOUND DATA PROCESSING
Published in IBRO neuroscience reports (01-10-2023)Get full text
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A deep learning classification task for brain navigation in rodents using micro-Doppler ultrasound imaging
Published in Heliyon (15-03-2024)“…Positioning and navigation are essential components of neuroimaging as they improve the quality and reliability of data acquisition, leading to advances in…”
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Whole-Brain Functional Ultrasound Imaging Reveals Brain Modules for Visuomotor Integration
Published in Neuron (Cambridge, Mass.) (05-12-2018)“…Large numbers of brain regions are active during behaviors. A high-resolution, brain-wide activity map could identify brain regions involved in specific…”
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Functional Ultrasound Neuroimaging
Published in Annual review of neuroscience (08-07-2022)“…Functional ultrasound (fUS) is a neuroimaging method that uses ultrasound to track changes in cerebral blood volume as an indirect readout of neuronal activity…”
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Functional ultrasound imaging of stroke in awake rats
Published in eLife (21-11-2023)“…Anesthesia is a major confounding factor in preclinical stroke research as stroke rarely occurs in sedated patients. Moreover, anesthesia affects both brain…”
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A Platform for Brain-wide Volumetric Functional Ultrasound Imaging and Analysis of Circuit Dynamics in Awake Mice
Published in Neuron (Cambridge, Mass.) (09-12-2020)“…Imaging large-scale circuit dynamics is crucial to understanding brain function, but most techniques have a limited depth of field. Here, we describe…”
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Whole-brain functional ultrasound imaging in awake head-fixed mice
Published in Nature protocols (01-07-2021)“…Most brain functions engage a network of distributed regions. Full investigation of these functions thus requires assessment of whole brains; however,…”
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Neural correlates of blood flow measured by ultrasound
Published in Neuron (Cambridge, Mass.) (18-05-2022)“…Functional ultrasound imaging (fUSI) is an appealing method for measuring blood flow and thus infer brain activity, but it relies on the physiology of…”
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Biology, host range, and risk assessment supporting release in Africa of Falconia intermedia (Heteroptera: Miridae), a new biocontrol agent for Lantana camara
Published in Biological control (2003)“…The ornamental hybrid shrub, Lantana camara L. (lantana), is a serious environmental weed and has been targeted for biological control in South Africa since…”
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Optogenetic fUSI for brain-wide mapping of neural activity mediating collicular-dependent behaviors
Published in Neuron (Cambridge, Mass.) (02-06-2021)“…Neuronal cell types are arranged in brain-wide circuits that guide behavior. In mice, the superior colliculus innervates a set of targets that direct orienting…”
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Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke
Published in Journal of cerebral blood flow and metabolism (01-01-2024)“…Ischemic stroke occurs abruptly causing sudden neurologic deficits, and therefore, very little is known about hemodynamic perturbations in the brain…”
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Circuit mechanism for suppression of frontal cortical ignition during NREM sleep
Published in Cell (21-12-2023)“…Conscious perception is greatly diminished during sleep, but the underlying circuit mechanism is poorly understood. We show that cortical ignition-a brain…”
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Chronic assessment of cerebral hemodynamics during rat forepaw electrical stimulation using functional ultrasound imaging
Published in NeuroImage (Orlando, Fla.) (01-11-2014)“…Functional ultrasound imaging is a method recently developed to assess brain activity via hemodynamics in rodents. Doppler ultrasound signals allow the…”
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Understanding the neurovascular unit at multiple scales: Advantages and limitations of multi-photon and functional ultrasound imaging
Published in Advanced drug delivery reviews (15-09-2017)“…Developing efficient brain imaging technologies by combining a high spatiotemporal resolution and a large penetration depth is a key step for better…”
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Genetic targeting of specific neuronal cell types in the cerebral cortex
Published in Progress in brain research (2012)“…Understanding the structure and function of cortical circuits requires the identification of and control over specific cell types in the cortex. To address…”
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Evidence from functional ultrasound imaging of enhanced contralesional microvascular response to somatosensory stimulation in acute middle cerebral artery occlusion/reperfusion in rats: A marker of ultra-early network reorganization?
Published in Journal of cerebral blood flow and metabolism (01-10-2018)“…Following middle cerebral artery (MCA) stroke, enhanced contralesional evoked responses have been consistently reported both in man and rodents as part of…”
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