Search Results - "Urakov, Valery N"
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A standard knockout procedure alters expression of adjacent loci at the translational level
Published in Nucleic acids research (08-11-2021)“…Abstract The Saccharomyces cerevisiae gene deletion collection is widely used for functional gene annotation and genetic interaction analyses. However, the…”
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Dangerous Stops: Nonsense Mutations Can Dramatically Increase Frequency of Prion Conversion
Published in International journal of molecular sciences (03-02-2021)“…Amyloid formation is associated with many incurable diseases. For some of these, sporadic cases are much more common than familial ones. Some reports point to…”
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The Pub1 and Upf1 Proteins Act in Concert to Protect Yeast from Toxicity of the [PSI⁺] Prion
Published in International journal of molecular sciences (20-11-2018)“…The [ ⁺] nonsense-suppressor determinant of is based on the formation of heritable amyloids of the Sup35 (eRF3) translation termination factor. [ ⁺] amyloids…”
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Ribo-Seq and RNA-Seq of TMA46 ( DFRP1) and GIR2 ( DFRP2) knockout yeast strains [version 1; peer review: 3 approved]
Published in F1000 research (2021)“…In eukaryotes, stalled and collided ribosomes are recognized by several conserved multicomponent systems, which either block protein synthesis in situ and…”
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CAR1 as a new selective marker for genetic engineering of wine yeasts
Published in Journal of microbiological methods (01-11-2023)“…A common problem in engineering industrial yeasts, and wine yeasts in particular, is the lack or scarcity of selective markers for introducing desired genetic…”
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Interdependence of amyloid formation in yeast: Implications for polyglutamine disorders and biological functions
Published in Prion (01-01-2010)“…In eukaryotic cells amyloid aggregates may incorporate various functionally unrelated proteins. In mammalian diseases this may cause amyloid toxicity, while in…”
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Ribosome‐bound Pub1 modulates stop codon decoding during translation termination in yeast
Published in The FEBS journal (01-06-2017)“…In eukaryotes, termination of translation is controlled by polypeptide chain release factors eRF1 and eRF3, of which the former recognizes nonsense codons,…”
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N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination
Published in BMC molecular biology (11-10-2006)“…Termination of translation in eukaryotes requires two release factors, eRF1, which recognizes all three nonsense codons and facilitates release of the nascent…”
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Itt1p, a novel protein inhibiting translation termination in Saccharomyces cerevisiae
Published in BMC molecular biology (24-08-2001)“…Termination of translation in eukaryotes is controlled by two interacting polypeptide chain release factors, eRFl and eRF3. eRFl recognizes nonsense codons…”
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10
A novel vacuolar protein encoded bySSU21 /MCD4 is involved in cell wall integrity in yeast
Published in Yeast (Chichester, England) (01-10-1999)Get full text
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11
A novel vacuolar protein encoded by SSU21 / MCD4 is involved in cell wall integrity in yeast
Published in Yeast (Chichester, England) (01-10-1999)“…Using a screening procedure for obtaining yeast strains with enhanced ability to secrete heterologous protein, we have isolated a mutant with alteration of the…”
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