Factors Associated With Adherence to Antiretroviral Therapy

Factors Associated With Adherence to Antiretroviral Therapy

The purpose of this study was to examine the relationship of sociodemographic characteristics, patient perceptions, and patient characteristics including spirituality, self-reported adherence, and highly active antiretroviral therapy. The convenience sample consisted of 120 English-speaking adults (...

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Bibliographic Details
Published in:The Journal of the Association of Nurses in AIDS Care Vol. 17; no. 2; pp. 4 - 15
Main Authors: McDonnell Holstad, Marcia K., Pace, James C., De, Anindya K., Ura, Darla R.
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-03-2006
Lippincott Williams & Wilkins Ovid Technologies
Subjects:
Acquired immune deficiency syndrome
adherence
Adult
AIDS
AIDS/HIV
Antiretroviral drugs
antiretroviral medications
Antiretroviral Therapy, Highly Active
Attitudes
Behavior
Factor Analysis, Statistical
Female
HAART
HIV
HIV Infections - drug therapy
HIV Infections - psychology
Human immunodeficiency virus
Humans
Male
Medical research
Middle Aged
Models, Psychological
Nursing
Patient Compliance - psychology
Patients
Regression Analysis
Social support
Southeastern United States
Spirituality
Southeastern United States
spirituality
antiretroviral medications
adherence
HAART
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Summary:The purpose of this study was to examine the relationship of sociodemographic characteristics, patient perceptions, and patient characteristics including spirituality, self-reported adherence, and highly active antiretroviral therapy. The convenience sample consisted of 120 English-speaking adults (60% male, 35% female, 5% transgendered) with HIV/AIDS from two HIV service agencies in a large metropolitan city in the southeastern United States. The mean self-reported adherence was 83.1% ( SD = 15.7%). Adherence was significantly correlated with perceived support and absence of barriers, strong intentions to adhere, perceived effectiveness of the medications, higher levels of perceived general health, fewer years of HIV disease, and fewer years on antiretroviral medications. Existential well-being (e.g., viewing life as positive and having meaning) was a weak significant correlate. Backward regression analysis was conducted to identify a parsimonious model of predictors of adherence. The final model included presence of support and absence of barriers, fewer years of HIV infection, no current alcohol use, perceived severity of HIV, existential well-being, and male gender. This model explained 19.4% of the variance in adherence (observed F[6, 100] = 5.6, p < .0001).
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1055-3290
1552-6917
DOI:10.1016/j.jana.2006.01.002