Search Results - "Uprichard, A C"

H2-receptor antagonism is not pro-arrhythmic in a chronic canine model by UPRICHARD, A. C. G, HARRON, D. W. G

“…Seven to 28 days after coronary artery ligation, programmed electrical stimulation was performed in conscious dogs. Groups of 6 previously inducible dogs in…”
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Atenolol, but not mexiletine, protects against stimulus‐induced ventricular tachycardia in a chronic canine model by Uprichard, A.C.G., Harron, D.W.G.

“…1 In a placebo‐controlled study of the antiarrhythmic and electrophysiological properties of atenolol and mexiletine, programmed electrical stimulation (PES)…”
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Lp (a) lipoprotein and impaired glucose tolerance: Association poorly investigated by Uprichard, A C G, Shurzinske, L

“…[...]even with the appropriate statistics and more confident data,retrospective case-control studies such as this should at best generate hypotheses:…”
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Celiprolol does not protect against ventricular tachycardia or sudden death in the conscious canine: a comparison with pindolol in assessing the role of intrinsic sympathomimetic activity by Uprichard, A C, Chi, L G, Kitzen, J M, Lynch, J J, Frye, J W, Lucchesi, B R

“…The antiarrhythmic and antifibrillatory effects of the beta-1 adrenoceptor antagonist celiprolol were evaluated in a chronic canine model of myocardial…”
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Profibrillatory actions of pinacidil in a conscious canine model of sudden coronary death by Chi, L, Uprichard, A C, Lucchesi, B R

“…Pinacidil is one of a number of new antihypertensive agents possessing an action that involves an enhanced potassium efflux in cardiac and vascular smooth…”
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Discovery and development of an endothelin A receptor-selective antagonist PD 156707 by Doherty, A M, Uprichard, A C

“…PD 156707 is a highly potent, selective antagonist of the ETA receptor that has demonstrated efficacy in a number of different disease models. The next few…”
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Resolution and electrophysiological effects of mexiletine enantiomers by Turgeon, J, Uprichard, A C, Bélanger, P M, Harron, D W, Grech-Bélanger, O

“…Resolution of mexiletine enantiomers from the racemic mixture has been achieved by fractional crystallization through the formation of diastereoisomeric…”
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The QUinapril ischemic event trial (QUIET) design and methods : evaluation of chronic ACE inhibitor therapy after coronary artery intervention by TEXTER, M, LEES, R. S, PITT, B, DINSMORE, R. E, UPRICHARD, A. C. G

“…The rationale, trial design, and statistical aspects of QUIET, the QUinapril Ischemic Event Trial, are described. QUIET is a prospective, double-blind…”
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Procainamide-associated blood dyscrasias by Danielly, Julie, DeJong, Richard, Radke-Mitchell, Lyn C., Uprichard, Andrew C.G.

“…Despite the rarity of procainamide-associated bone marrow suppression, it is imperative that the patient and treating physician follow labeling precautions…”
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Pharmacokinetic and pharmacodynamic comparisons of twice daily and four times daily formulations of procainamide in patients with frequent ventricular premature depolarization by Yang, B B, Abel, R B, Uprichard, A C, Smithers, J A, Forgue, S T

“…A study was conducted to evaluate the pharmacokinetics of procainamide and its active metabolite, N-acetylprocainamide (NAPA), as a function of dose and…”
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Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study by Mancini, G B, Henry, G C, Macaya, C, O'Neill, B J, Pucillo, A L, Carere, R G, Wargovich, T J, Mudra, H, Lüscher, T F, Klibaner, M I, Haber, H E, Uprichard, A C, Pepine, C J, Pitt, B

“…Angiotensin-converting enzyme (ACE) inhibitors may exert some of their benefits in the therapy of hypertension, congestive heart failure, and acute myocardial…”
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Antiarrhythmic versus antifibrillatory actions: Inference from experimental studies by Lucchesi, Benedict R., Chi, Liguo, Friedrichs, Gregory S., Black, Shawn C., Uprichard, Andrew C.G.

“…Pathophysiology of the coronary circulation is a major contributor to altering the myocardial substrate, rendering the heart susceptible to the onset of…”
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Hypothyroidism renders protection against lethal ventricular arrhythmias in a conscious canine model of sudden death by Venkatesh, N, Lynch, J J, Uprichard, A C, Kitzen, J M, Singh, B N, Lucchesi, B R

“…The protective effect of hypothyroidism against lethal ventricular tachyarrhythmias (VT) in the subacute phase of experimental myocardial infarction (MI) was…”
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Do enzymatic analyses of serum triglycerides really need blanking for free glycerol? by Uprichard, A C, Shurzinske, L, Watts, A R, Nawrocki, J W

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Effects of the positive inotropic agents milrinone and pimobendan on the development of lethal ischemic arrhythmias in conscious dogs with recent myocardial infarction by Lynch, Jr, J J, Uprichard, A C, Frye, J W, Driscoll, E M, Kitzen, J M, Lucchesi, B R

“…The effects of milrinone and pimobendan upon the initiation of programmed ventricular stimulation-induced ventricular tachycardia (VT) and the incidence of…”
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Effects of tocainide enantiomers on experimental arrhythmias produced by programmed electrical stimulation by Uprichard, A C, Allen, J D, Harron, D W

“…The enantiomers of tocainide, a Class Ib antiarrhythmic agent, have recently been shown to exhibit differences in antiarrhythmic activity and pharmacokinetic…”
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Alinidine reduces the incidence of ischemic ventricular fibrillation in a conscious canine model, a protective effect antagonized by overdrive atrial pacing by Uprichard, A C, Chi, L G, Lynch, J J, Driscoll, E M, Frye, J W, Lucchesi, B R

“…The antiarrhythmic and antifibrillatory effects of the specific bradycardic agent alinidine were evaluated in a conscious canine model of myocardial infarction…”
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Effects of combined thromboxane synthetase inhibition/thromboxane receptor antagonism in two models of sudden cardiac death in the canine: limited role for thromboxane by Kitzen, J M, Chi, L G, Uprichard, A C, Lucchesi, B R

“…The effects of combined thromboxane synthetase inhibition and thromboxane receptor antagonism (TSI/TRA) were studied in conscious and in anesthetized canine…”
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Fatal Listeria monocytogenes meningitis in two previously healthy adults by Uprichard, A C, Logan, K R

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Management of severe theophylline overdosage by charcoal haemoperfusion by Uprichard, A C, Bailie, R, McAteer, E

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