Search Results - "Uppuluri, Lahari"

Multiplex structural variant detection by whole-genome mapping and nanopore sequencing by Uppuluri, Lahari, Wang, Yilin, Young, Eleanor, Wong, Jessica S., Abid, Heba Z., Xiao, Ming

“…Identification of structural variants (SVs) breakpoints is important in studying mutations, mutagenic causes, and functional impacts. Next-generation…”
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A long-read sequencing strategy with overlapping linkers on adjacent fragments (OLAF-Seq) for targeted resequencing and enrichment by Uppuluri, Lahari, Shi, Christina Huan, Varapula, Dharma, Young, Eleanor, Ehrlich, Rachel L., Wang, Yilin, Piazza, Danielle, Mell, Joshua Chang, Yip, Kevin Y., Xiao, Ming

“…In this report, we present OLAF-Seq, a novel strategy to construct a long-read sequencing library such that adjacent fragments are linked with end-terminal…”
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Optical mapping of the 22q11.2DS region reveals complex repeat structures and preferred locations for non-allelic homologous recombination (NAHR) by Pastor, Steven, Tran, Oanh, Jin, Andrea, Carrado, Danielle, Silva, Benjamin A., Uppuluri, Lahari, Abid, Heba Z., Young, Eleanor, Crowley, T. Blaine, Bailey, Alice G., McGinn, Daniel E., McDonald-McGinn, Donna M., Zackai, Elaine H., Xie, Michael, Taylor, Deanne, Morrow, Bernice E., Xiao, Ming, Emanuel, Beverly S.

“…The most prevalent microdeletion in humans occurs at 22q11.2, a region rich in chromosome-specific low copy repeats (LCR22s). The structure of this region has…”
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Multicolor Whole-Genome Mapping in Nanochannels for Genetic Analysis by Uppuluri, Lahari, Jadhav, Tanaya, Wang, Yilin, Xiao, Ming

“…Analysis of structural variations (SVs) is important to understand mutations underlying genetic disorders and pathogenic conditions. However, characterizing…”
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Single-molecule telomere length characterization by optical mapping in nano-channel array: Perspective and review on telomere length measurement by Uppuluri, Lahari, Varapula, Dharma, Young, Eleanor, Riethman, Harold, Xiao, Ming

“…•Telomere length can be used as a biomarker for aging, cancer, and DNA damage.•Telomere length characterization beyond average length measurement is…”
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IL-10 Levels Differentially Regulate IFNg Signaling of CART19 and CART22 by Diorio, Caroline, Myers, Regina M., Frank-Kamenetski, Anastasia, Shraim, Rawan, Dinofia, Amanda M., Martinez, Zachary, Mustafa, Ohaila, Fraietta, Joseph A, Gonzalez, Vanessa, Yi, Vivian, Uppuluri, Lahari, Newman, Haley, Behrens, Edward, June, Carl, Canna, Scott, Grupp, Stephan, Teachey, David T.

“…Introduction: CD19-directed CART (CART19) are highly effective in the treatment of relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL). However,…”
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Gold silver alloy nanoparticles (GSAN): an imaging probe for breast cancer screening with dual-energy mammography or computed tomography by Naha, Pratap C, Lau, Kristen C, Hsu, Jessica C, Hajfathalian, Maryam, Mian, Shaameen, Chhour, Peter, Uppuluri, Lahari, McDonald, Elizabeth S, Maidment, Andrew D A, Cormode, David P

“…Earlier detection of breast cancer reduces mortality from this disease. As a result, the development of better screening techniques is a topic of intense…”
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A micropatterned substrate for on-surface enzymatic labelling of linearized long DNA molecules by Varapula, Dharma, LaBouff, Eric, Raseley, Kaitlin, Uppuluri, Lahari, Ehrlich, Garth D., Noh, Moses, Xiao, Ming

“…Optical mapping of linearized DNA molecules is a promising new technology for sequence assembly and scaffolding, large structural variant detection, and…”
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The genomic basis of childhood T-lineage acute lymphoblastic leukaemia by Pölönen, Petri, Di Giacomo, Danika, Seffernick, Anna Eames, Elsayed, Abdelrahman, Kimura, Shunsuke, Benini, Francesca, Montefiori, Lindsey E., Wood, Brent L., Xu, Jason, Chen, Changya, Cheng, Zhongshan, Newman, Haley, Myers, Jason, Iacobucci, Ilaria, Li, Elizabeth, Sussman, Jonathan, Hedges, Dale, Hui, Yawei, Diorio, Caroline, Uppuluri, Lahari, Frank, David, Fan, Yiping, Chang, Yunchao, Meshinchi, Soheil, Ries, Rhonda, Shraim, Rawan, Li, Alexander, Bernt, Kathrin M., Devidas, Meenakshi, Winter, Stuart S., Dunsmore, Kimberly P., Inaba, Hiroto, Carroll, William L., Ramirez, Nilsa C., Phillips, Aaron H., Kriwacki, Richard W., Yang, Jun J., Vincent, Tiffaney L., Zhao, Yaqi, Ghate, Pankaj S., Wang, Jian, Reilly, Colleen, Zhou, Xin, Sanders, Mathijs A., Takita, Junko, Kato, Motohiro, Takasugi, Nao, Chang, Bill H., Press, Richard D., Loh, Mignon, Rampersaud, Evadnie, Raetz, Elizabeth, Hunger, Stephen P., Tan, Kai, Chang, Ti-Cheng, Wu, Gang, Pounds, Stanley B., Mullighan, Charles G., Teachey, David T.

“…T-lineage acute lymphoblastic leukaemia (T-ALL) is a high-risk tumour 1 that has eluded comprehensive genomic characterization, which is partly due to the high…”
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The genomic basis of childhood T-lineage acute lymphoblastic leukaemia by Pölönen, Petri, Di Giacomo, Danika, Seffernick, Anna Eames, Elsayed, Abdelrahman, Kimura, Shunsuke, Benini, Francesca, Montefiori, Lindsey E, Wood, Brent L, Xu, Jason, Chen, Changya, Cheng, Zhongshan, Newman, Haley, Myers, Jason, Iacobucci, Ilaria, Li, Elizabeth, Sussman, Jonathan, Hedges, Dale, Hui, Yawei, Diorio, Caroline, Uppuluri, Lahari, Frank, David, Fan, Yiping, Chang, Yunchao, Meshinchi, Soheil, Ries, Rhonda, Shraim, Rawan, Li, Alexander, Bernt, Kathrin M, Devidas, Meenakshi, Winter, Stuart S, Dunsmore, Kimberly P, Inaba, Hiroto, Carroll, William L, Ramirez, Nilsą C, Phillips, Aaron H, Kriwacki, Richard W, Yang, Jun J, Vincent, Tiffaney L, Zhao, Yaqi, Ghate, Pankaj S, Wang, Jian, Reilly, Colleen, Zhou, Xin, Sanders, Mathijs A, Takita, Junko, Kato, Motohiro, Takasugi, Nao, Chang, Bill H, Press, Richard D, Loh, Mignon, Rampersaud, Evadnie, Raetz, Elizabeth, Hunger, Stephen P, Tan, Kai, Chang, Ti-Cheng, Wu, Gang, Pounds, Stanley B, Mullighan, Charles G, Teachey, David T

“…T-lineage acute lymphoblastic leukaemia (T-ALL) is a high-risk tumour1 that has eluded comprehensive genomic characterization, which is partly due to the high…”
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Abstract B051: Marrow and peripheral blood cytokine architecture differences between pediatric patients receiving CD19- and CD22-directed CART by Diorio, Caroline, Uppuluri, Lahari, Thadi, Anusha, Myers, Regina, Shraim, Rawan, Dinofia, Amanda, Martinez, Zachary, Elhachimi, Amira, Fraietta, Joseph, Gonzalez, Vanessa, Yi, Vivian, Newman, Haley, Hughes, Andrew, Tan, Kai, Grupp, Stephan, Teachey, David T.

“…Abstract Introduction: Chimeric antigen receptor T-cell (CART) targeting CD19 (CART19) have revolutionized therapy for relapsed/refractory pediatric B-cell…”
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