Search Results - "Updegrove, Taylor B"

The Ubiquitous yybP-ykoY Riboswitch Is a Manganese-Responsive Regulatory Element by Dambach, Michael, Sandoval, Melissa, Updegrove, Taylor B., Anantharaman, Vivek, Aravind, L., Waters, Lauren S., Storz, Gisela

“…The highly structured, cis-encoded RNA elements known as riboswitches modify gene expression upon binding a wide range of molecules. The yybP-ykoY motif was…”
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Three-dimensional structured illumination microscopy with enhanced axial resolution by Li, Xuesong, Wu, Yicong, Su, Yijun, Rey-Suarez, Ivan, Matthaeus, Claudia, Updegrove, Taylor B., Wei, Zhuang, Zhang, Lixia, Sasaki, Hideki, Li, Yue, Guo, Min, Giannini, John P., Vishwasrao, Harshad D., Chen, Jiji, Lee, Shih-Jong J., Shao, Lin, Liu, Huafeng, Ramamurthi, Kumaran S., Taraska, Justin W., Upadhyaya, Arpita, La Riviere, Patrick, Shroff, Hari

“…The axial resolution of three-dimensional structured illumination microscopy (3D SIM) is limited to ∼300 nm. Here we present two distinct, complementary…”
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Dual-function AzuCR RNA modulates carbon metabolism by Raina, Medha, Aoyama, Jordan J, Bhatt, Shantanu, Paul, Brian J, Zhang, Aixia, Updegrove, Taylor B, Miranda-Ríos, Juan, Storz, Gisela

“…SignificanceWhile most small, regulatory RNAs are thought to be "noncoding," a few have been found to also encode a small protein. Here we describe a…”
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A 2-dimensional ratchet model describes assembly initiation of a specialized bacterial cell surface by Peluso, Emily A., Updegrove, Taylor B., Chen, Jiji, Shroff, Hari, Ramamurthi, Kumaran S.

“…Bacterial spores are dormant cells that are encased in a thick protein shell, the “coat,” which participates in protecting the organism’s DNA from…”
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Cell-specific cargo delivery using synthetic bacterial spores by Kong, Minsuk, D’Atri, Domenico, Bilotta, Maria Teresa, Johnson, Bailey, Updegrove, Taylor B., Gallardo, Devorah L., Machinandiarena, Federico, Wu, I-Lin, Constantino, Maira Alves, Hewitt, Stephen M., Tanner, Kandice, Fitzgerald, David J., Ramamurthi, Kumaran S.

“…Delivery of cancer therapeutics to non-specific sites decreases treatment efficacy while increasing toxicity. In ovarian cancer, overexpression of the cell…”
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Hfq: the flexible RNA matchmaker by Updegrove, Taylor B, Zhang, Aixia, Storz, Gisela

“…Graphical abstract…”
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Reformulation of an extant ATPase active site to mimic ancestral GTPase activity reveals a nucleotide base requirement for function by Updegrove, Taylor B, Harke, Jailynn, Anantharaman, Vivek, Yang, Jin, Gopalan, Nikhil, Wu, Di, Piszczek, Grzegorz, Stevenson, David M, Amador-Noguez, Daniel, Wang, Jue D, Aravind, L, Ramamurthi, Kumaran S

“…Hydrolysis of nucleoside triphosphates releases similar amounts of energy. However, ATP hydrolysis is typically used for energy-intensive reactions, whereas…”
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How do base-pairing small RNAs evolve? by Updegrove, Taylor B., Shabalina, Svetlana A., Storz, Gisela

“…The increasing numbers of characterized base-pairing small RNAs (sRNAs) and the identification of these regulators in a broad range of bacteria are allowing…”
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Stem-loops direct precise processing of 3′ UTR-derived small RNA MicL by Updegrove, Taylor B, Kouse, Andrew B, Bandyra, Katarzyna J, Storz, Gisela

“…Abstract Increasing numbers of 3′UTR-derived small, regulatory RNAs (sRNAs) are being discovered in bacteria, most generated by cleavage from longer…”
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Multiple factors dictate target selection by Hfq-binding small RNAs by Beisel, Chase L, Updegrove, Taylor B, Janson, Ben J, Storz, Gisela

“…Hfq‐binding small RNAs (sRNAs) in bacteria modulate the stability and translational efficiency of target mRNAs through limited base‐pairing interactions. While…”
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Cell division machinery drives cell-specific gene activation during differentiation in Bacillus subtilis by Chareyre, Sylvia, Li, Xuesong, Anjuwon-Foster, Brandon R, Updegrove, Taylor B, Clifford, Sarah, Brogan, Anna P, Su, Yijun, Zhang, Lixia, Chen, Jiji, Shroff, Hari, Ramamurthi, Kumaran S

“…When faced with starvation, the bacterium transforms itself into a dormant cell type called a "spore". Sporulation initiates with an asymmetric division event,…”
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Bacterial spore surface nanoenvironment requires a AAA+ ATPase to promote MurG function by Delerue, Thomas, Updegrove, Taylor B, Chareyre, Sylvia, Anantharaman, Vivek, Gilmore, Michael C, Jenkins, Lisa M, Popham, David L, Cava, Felipe, Aravind, L, Ramamurthi, Kumaran S

“…spores are produced inside the cytosol of a mother cell. Spore surface assembly requires the SpoVK protein in the mother cell, but its function is unknown…”
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Geometric protein localization cues in bacterial cells by Updegrove, Taylor B, Ramamurthi, Kumaran S

“…Highlights • Bacteria localize proteins to distinct subcellular locations. • Membrane curvature (convex or concave) can be a beacon to recruit certain…”
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Protection against deleterious nitrogen compounds: role of σS-dependent small RNAs encoded adjacent to sdiA by Hao, Yue, Updegrove, Taylor B, Livingston, Natasha N, Storz, Gisela

“…Here, we report the characterization of a set of small, regulatory RNAs (sRNAs) expressed from an Escherichia coli locus we have denoted sdsN located adjacent…”
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Vaccine display on artificial bacterial spores enhances protective efficacy against Staphylococcus aureus infection by Karauzum, Hatice, Updegrove, Taylor B, Kong, Minsuk, Wu, I-Lin, Datta, Sandip K, Ramamurthi, Kumaran S

“…Spores of Bacillus subtilis are encased in a protein coat composed of ∼80 different proteins. Recently, we reconstituted the basement layer of the coat,…”
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The stoichiometry of the Escherichia coli Hfq protein bound to RNA by Updegrove, Taylor B, Correia, John J, Chen, Yanfeng, Terry, Charles, Wartell, Roger M

“…The Escherichia coli RNA binding protein Hfq is involved in many aspects of post-transcriptional gene expression. Tight binding of Hfq to polyadenylate…”
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The influence of Escherichia coli Hfq mutations on RNA binding and sRNA•mRNA duplex formation in rpoS riboregulation by Updegrove, Taylor B., Wartell, Roger M.

“…The Escherichia coli RNA binding protein Hfq plays an important role in regulating mRNA translation through its interactions with small non-coding RNAs (sRNAs)…”
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PcdA promotes orthogonal division plane selection in Staphylococcus aureus by Ramos-León, Félix, Anjuwon-Foster, Brandon R., Anantharaman, Vivek, Updegrove, Taylor B., Ferreira, Colby N., Ibrahim, Amany M., Tai, Chin-Hsien, Kruhlak, Michael J., Missiakas, Dominique M., Camberg, Jodi L., Aravind, L., Ramamurthi, Kumaran S.

“…The bacterial pathogen, Staphylococcus aureus , grows by dividing in two alternating orthogonal planes. How these cell division planes are positioned correctly…”
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Altruistic feeding and cell-cell signaling during bacterial differentiation actively enhance phenotypic heterogeneity by Updegrove, Taylor B, Delerue, Thomas, Anantharaman, Vivek, Cho, Hyomoon, Chan, Carissa, Nipper, Thomas, Choo-Wosoba, Hyoyoung, Jenkins, Lisa M, Zhang, Lixia, Su, Yijun, Shroff, Hari, Chen, Jiji, Bewley, Carole A, Aravind, L, Ramamurthi, Kumaran S

“…Starvation triggers bacterial spore formation, a committed differentiation program that transforms a vegetative cell into a dormant spore. Cells in a…”
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E. coli DNA associated with isolated Hfq interacts with Hfq's distal surface and C-terminal domain by Updegrove, Taylor B., Correia, John J., Galletto, Roberto, Bujalowski, Wlodzimierz, Wartell, Roger M.

“…The RNA-binding protein Hfq has been studied extensively for its function as a modulator of gene expression at the post-transcriptional level. While most Hfq…”
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