Search Results - "Upadhye, Trupti"
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Automated radiosynthesis of pharmaceutical grade [68Ga]Ga-NODAGA-Lys40-Exendin-4 and demonstration of its efficacy for use in patients
Published in Journal of radioanalytical and nuclear chemistry (01-08-2024)“…The radiosynthesis of pharmaceutical grade [ 68 Ga]Ga-NODAGA-Lys 40 -Exendin-4 was accomplished in a fixed tubing-based module, EZ Modular-Lab Standard…”
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Intricacies in the Preparation of Patient Doses of [177Lu]Lu-Rituximab and [177Lu]Lu-Trastuzumab Using Low Specific Activity [177Lu]LuCl3: Methodological Aspects
Published in Molecular imaging and biology (01-02-2024)“…The development of humanized monoclonal antibodies (MAbs) with Lutetium-177 ([ 177 Lu]Lu 3+ ) has brought a paradigm shift in the arena of targeted therapy of…”
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Synthesis and evaluation of [177Lu]Lu‐labeled porphyrin loaded PAMAM dendrimer: Impact on tumor uptake and pharmacokinetics
Published in Drug development research (01-12-2022)“…The objective of the present work is to evaluate the ability of the radiolabeled PAMAM dendrimers (polyamidoamine) towards facilitating the delivery of an…”
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Clinical efficacy of Sep-Pak® assisted one pot automated synthesis of pharmaceutical grade [18F]FLT using 5′-O-(benzoyl)-2,3′-anhydrothymidine precursor
Published in Journal of radioanalytical and nuclear chemistry (2021)“…An automated production of pharmaceutical grade 3′-deoxy-3′-[ 18 F]fluorothymidine ([ 18 F]FLT) with solid phase extraction (SPE) purification using…”
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On the production of pharmaceutical grade indium-111-chloride in the medical cyclotron from natural cadmium target and its use in formulation of diagnostic patient dose of 111In-pentetreotide for imaging somatostatin receptor overexpression
Published in Journal of radioanalytical and nuclear chemistry (2021)“…A prototype, semi-automated, indigenous solid-target assembly has been developed to produce clinical grade 111 InCl 3 from nat Cd targets. Fluka Monte Carlo…”
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Unusual Case of Adrenal and Renal Metastases From Papillary Carcinoma of Thyroid
Published in Clinical nuclear medicine (01-09-2010)“…We report a rare case of adrenal and renal metastases from papillary thyroid carcinoma (PTC). A 30-year-old man underwent total thyroidectomy with left neck…”
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Evaluation of 18F-FDG Uptake Pattern in Brown Adipose Tissue Over Extended Time Period as Assessed by Multiple Time Point 18F-FDG-PET
Published in Nuclear medicine and molecular imaging (01-06-2013)“…Purpose To study the 18 F-FDG uptake pattern in brown adipose tissue (BAT) over an extended time period, by multiple-time-point fluorodeoxyglucose positron…”
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Can Carbonated Lime Drink Intake Prior to Myocardial Perfusion Imaging With Tc-99m MIBI Reduce the Extracardiac Activity That Degrades the Image Quality and Leads to Fallacies in Interpretation?
Published in Clinical nuclear medicine (01-03-2010)“…BACKGROUND:During myocardial perfusion imaging with Tc-99m sestamibi, intestinal and hepatic radiotracer activity commonly interfere with visualization of the…”
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Unilateral Proptosis Due to Orbital Metastasis as a Presenting Clinical Manifestation of Carcinoma of the Thyroid
Published in Clinical nuclear medicine (01-05-2010)“…Differentiated thyroid cancers commonly present with thyroid swelling with or without regional nodal involvement and usually have an indolent clinical course…”
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Sellar-Parasellar and Petrous Bone Metastasis from Differentiated Thyroid Carcinoma: Imaging Characteristics and Follow-Up Profile Post Radioiodine Therapy
Published in World journal of nuclear medicine (01-06-2023)“…Sella turcica and petrous bone metastasis from differentiated thyroid carcinoma are rare clinical entities, with only a few limited cases reported to date. Two…”
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Suicidal behaviour: What's the brain up to?
Published in Journal of psychiatric research (01-02-2022)“…Individuals with suicidal behaviours are increasingly recognized as having impairments in brain metabolism. However, these are not well delineated. To evaluate…”
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Pathological extracardiac uptake of Tc-99m sestamibi (MIBI) leading to a false impression of reduced wall thickening in a region of apparent hyperperfusion on gated myocardial perfusion single photon emission computed tomography (G-SPECT)
Published in BMJ case reports (2009)“…A 55-year-old male patient without known coronary risk factors was subjected to gated myocardial perfusion single photon emission computed tomography (G-SPECT)…”
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Reversal of Basal Ganglia Hypermetabolism Following Surgical Removal of Adrenocorticotropic Hormone-Producing Lung Carcinoid in a Patient of Cushing Syndrome With Unusual Presentation of Acute Psychosis: Proof of Concept
Published in Clinical nuclear medicine (01-12-2024)“…A 34-year-old woman who presented with severe psychosis and clinical features of Cushing syndrome underwent 18F-FDG PET/CT that revealed hypermetabolic lung…”
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On the production of pharmaceutical grade indium-111-chloride in the medical cyclotron from natural cadmium target and its use in formulation of diagnostic patient dose of .sup.111In-pentetreotide for imaging somatostatin receptor overexpression
Published in Journal of radioanalytical and nuclear chemistry (01-06-2021)“…A prototype, semi-automated, indigenous solid-target assembly has been developed to produce clinical grade .sup.111InCl.sub.3 from .sup.natCd targets. Fluka…”
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A robust lyophilized kit for convenient one-step formulation of [68Ga]Ga-DOTA-E−[c(RGDfK)]2 in hospital radiopharmacy for clinical PET imaging
Published in Applied radiation and isotopes (01-06-2023)“…The present article describes the development of robust lyophilized kit for convenient formulation of [68Ga]Ga-DOTA-E−[c(RGDfK)]2 (E = glutamic acid, R =…”
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Clinical efficacy of Sep-Pak.sup.® assisted one pot automated synthesis of pharmaceutical grade [.sup.18F]FLT using 5'-O--2,3'-anhydrothymidine precursor
Published in Journal of radioanalytical and nuclear chemistry (01-01-2021)“…An automated production of pharmaceutical grade 3'-deoxy-3'-[.sup.18F]fluorothymidine ([.sup.18F]FLT) with solid phase extraction (SPE) purification using…”
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