Search Results - "Upadhye, Sampada B."

Pharmaceutical Applications of Hot-Melt Extrusion: Part I by Crowley, Michael M., Zhang, Feng, Repka, Michael A., Thumma, Sridhar, Upadhye, Sampada B., Kumar Battu, Sunil, McGinity, James W., Martin, Charles

“…Interest in hot-melt extrusion techniques for pharmaceutical applications is growing rapidly with well over 100 papers published in the pharmaceutical…”
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Applications of hot-melt extrusion for drug delivery by Repka, Michael A, Majumdar, Soumyajit, Kumar Battu, Sunil, Srirangam, Ramesh, Upadhye, Sampada B

“…In today's pharmaceutical arena, it is estimated that more than 40% of new chemical entities produced during drug discovery efforts exhibit poor solubility…”
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Formulation and development of pH-independent/dependent sustained release matrix tablets of ondansetron HCl by a continuous twin-screw melt granulation process by Patil, Hemlata, Tiwari, Roshan V., Upadhye, Sampada B., Vladyka, Ronald S., Repka, Michael A.

“…[Display omitted] The objective of the present study was to develop pH-independent/dependent sustained release (SR) tablets of ondansetron HCl dihydrate (OND),…”
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Pharmaceutical Applications of Hot-Melt Extrusion: Part II by Repka, Michael A., Battu, Sunil Kumar, Upadhye, Sampada B., Thumma, Sridhar, Crowley, Michael M., Zhang, Feng, Martin, Charles, McGinity, James W.

“…The advent of high through-put screening in the drug discovery process has resulted in compounds with high lipophilicity and poor solubility. Increasing the…”
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In Vitro Characterization of a Novel Polymeric System for Preparation of Amorphous Solid Drug Dispersions by Mahmoudi, Zahra N., Upadhye, Sampada B., Ferrizzi, David, Rajabi-Siahboomi, Ali R.

“…Preparation of amorphous solid dispersions using polymers is a commonly used formulation strategy for enhancing the solubility of poorly water-soluble drugs…”
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Preparation and Characterization of Inclusion Complexes of a Hemisuccinate Ester Prodrug of Δ9-Tetrahydrocannabinol with Modified Beta-Cyclodextrins by Upadhye, Sampada B., Kulkarni, Swapnil J., Majumdar, Soumyajit, Avery, Mitchell A., Gul, Waseem, ElSohly, Mahmoud A., Repka, Michael A.

“…Δ 9 -Tetrahydrocannabinol hemisuccinate (THC-HS), an ester prodrug of Δ 9 -tetrahydrocannabinol (THC) has been investigated for its potential to form inclusion…”
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Preparation and Characterization of Inclusion Complexes of a Hemisuccinate Ester Prodrug of Delta D9-Tetrahydrocannabinol with Modified Beta-Cyclodextrins by Upadhye, Sampada B, Kulkarni, Swapnil J, Majumdar, Soumyajit, Avery, Mitchell A, Gul, Waseem, Elsohly, Mahmoud A, Repka, Michael A

“…Delta *D9-Tetrahydrocannabinol hemisuccinate (THC-HS), an ester prodrug of Delta *D9-tetrahydrocannabinol (THC) has been investigated for its potential to form…”
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Preparation and characterization of lyophilized cyclodextrin complexes of a hemisuccinate ester of delta-9-tetrahydrocannabinol for transmucosal delivery by Upadhye, Sampada B

“…Δ9-Tetrahydrocannabinol (THC) is the primary active ingredient of the plant Cannabis sativa (marijuana), responsible for the majority of the pharmacological…”
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Preparation and characterization of inclusion complexes of a hemisuccinate ester prodrug of delta9-tetrahydrocannabinol with modified beta-cyclodextrins by Upadhye, Sampada B, Kulkarni, Swapnil J, Majumdar, Soumyajit, Avery, Mitchell A, Gul, Waseem, ElSohly, Mahmoud A, Repka, Michael A

“…Delta(9)-Tetrahydrocannabinol hemisuccinate (THC-HS), an ester prodrug of Delta(9)-tetrahydrocannabinol (THC) has been investigated for its potential to form…”
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